Consulta: creatorFacets:"Forterre, Patrick"
Registros recuperados: 3
Data/hora: 09/06/2024 02:47:57

Insights into Dynamics of Mobile Genetic Elements in Hyperthermophilic Environments from Five New Thermococcus Plasmids
Provedor de dados: 5
Autores: Krupovic, Mart; Gonnet, Mathieu; Ben Hania, Wajdi; Forterre, Patrick; Erauso, Gael.
Mobilome of hyperthermophilic archaea dwelling in deep-sea hydrothermal vents is poorly characterized. To gain insight into genetic diversity and dynamics of mobile genetic elements in these environments we have sequenced five new plasmids from different Thermococcus strains that have been isolated from geographically remote hydrothermal vents. The plasmids were ascribed to two subfamilies, pTN2-like and pEXT9a-like. Gene content and phylogenetic analyses illuminated a robust connection between pTN2-like plasmids and Pyrococcus abyssi virus 1 (PAV1), with roughly half of the viral genome being composed of genes that have homologues in plasmids. Unexpectedly, pEXT9a-like plasmids were found to be closely related to the previously sequenced plasmid pMETVU01...
Tipo: Text
Ano: 2013
URL: http://archimer.ifremer.fr/doc/00125/23583/21434.pdf

An abyssal mobilome: Viruses, plasmids and vesicles from deep-sea hydrothermal vents
Provedor de dados: 5
Autores: Lossouarn, Julien; Dupont, Samuel; Gorlas, Aurore; Mercier, Coraline; Bienvenu, Nadege; Marguet, Evelyne; Forterre, Patrick; Geslin, Claire.
Mobile genetic elements (MGEs) such as viruses, plasmids, vesicles, gene transfer agents (GTAs), transposons and transpovirions, which collectively represent the mobilome, interact with cellular organisms from all three domains of life, including those thriving in the most extreme environments. While efforts have been made to better understand deep-sea vent microbial ecology, our knowledge of the mobilome associated with prokaryotes inhabiting deep-sea hydrothermal vents remains limited. Here we focus on the abyssal mobilome by reviewing accumulating data on viruses, plasmids and vesicles associated with thermophilic and hyperthermophilic Bacteria and Archaea present in deep-sea hydrothermal vents.
Tipo: Text
Palavras-chave: Deep-sea hydrothermal vent; Bacteria; Archaea; (Hyper-)thermophiles; Mobilome.
Ano: 2015
URL: http://archimer.ifremer.fr/doc/00260/37145/36731.pdf

Pervasive suicidal integrases in deep-sea archaea
Provedor de dados: 5
Autores: Badel, Catherine; Da Cunha, Violette; Forterre, Patrick; Oberto, Jacques.
Mobile genetic elements often encode integrases which catalyze the site-specific insertion of their genetic information into the host genome and the reverse reaction of excision. Hyperthermophilic archaea harbor integrases belonging to the SSV-family which carry the MGE recombination site within their open reading frame. Upon integration into the host genome, SSV integrases disrupt their own gene into two inactive pseudogenes and are termed suicidal for this reason. The evolutionary maintenance of suicidal integrases, concurring with the high prevalence and multiples recruitments of these recombinases by archaeal MGEs, is highly paradoxical. To elucidate this phenomenon, we analyzed the wide phylogenomic distribution of a prominent class of suicidal...
Tipo: Text
Ano: 2020
URL: https://archimer.ifremer.fr/doc/00610/72166/70937.pdf