Consulta: creatorFacets:"Gerardi,Daniel"
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Immunohistochemical expression of B and T-lymphocytes and TGF-β in experimentally transplanted canine venereal tumor
Provedor de dados: 65
Autores: Silveira,Ana Carolina Trompieri; Gerardi,Daniel; Mouro,Juliana Vitti; Costa,Mirela Tinucci; Alessi,Antonio Carlos.
The tumor/host relationship may have a determining role in the progression or remission of a tumor. Greater infiltration of leukocytes into tumors has been associated with a better prognosis, although controversy regarding whether these cells have a central role in antitumor immunity still exists. Canine transmissible venereal tumor (TVT) is an experimentally transplantable type of tumor that has been used as an experimental model for the tumor/host relationship. The aim of this study was to evaluate the infiltration of T-lymphocytes (CD3, CD4, CD8) and B lymphocytes (CD79-α) and the expression of the cytokine TGF-β in TVT, by means of immunohistochemistry (ABC method). The experimental tumors were composed of puppies that developed TVT after...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Lymphocytes; TVT; Immunohistochemistry; Dog.
Ano: 2009
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782009000400029