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Antifungal activity of different neem leaf extracts and the nimonol against some important human pathogens
Provedor de dados: 58
Autores: Mahmoud,D.A; Hassanein,N.M; Youssef,K.A; Abou Zeid,M.A.
This study was conducted to evaluate the effect of aqueous, ethanolic and ethyl acetate extracts from neem leaves on growth of some human pathogens (Aspergillus flavus, Aspergillus fumigatus, Aspergillus niger, Aspergillus terreus, Candida albicans and Microsporum gypseum) in vitro. Different concentrations (5, 10, 15 and 20%) prepared from these extracts inhibited the growth of the test pathogens and the effect gradually increased with concentration. The 20% ethyl acetate extract gave the strongest inhibition compared with the activity obtained by the same concentration of the other extracts. High Performance Liquid Chromatography (HPLC) analysis of ethyl acetate extract showed the presence of a main component (nimonol) which was purified and chemically...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Azadirachta indica; Aqueous and organic extracts; HPLC; Fungal inhibitory effect.
Ano: 2011
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822011000300021