Consulta: creatorFacets:"Kitten,G.T."
Registros recuperados: 2
Data/hora: 09/06/2024 10:33:00

Expression of beta 2 integrin (CD18) in embryonic mouse and chicken heart
Provedor de dados: 56
Autores: Oliveira,L.A.M.; Baker,R.K.; Klewer,S.E.; Kitten,G.T.
Integrins are heterodimeric receptors composed of α and β transmembrane subunits that mediate attachment of cells to the extracellular matrix and counter-ligands such as ICAM-1 on adjacent cells. β2 integrin (CD18) associates with four different α (CD11) subunits to form an integrin subfamily, which has been reported to be expressed exclusively on leukocytes. However, recent studies indicate that β2 integrin is also expressed by other types of cells. Since the gene for β2 integrin is located in the region of human chromosome 21 associated with congenital heart defects, we postulated that it may be expressed in the developing heart. Here, we show the results from several different techniques used to test this hypothesis. PCR analyses indicated that β2...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Beta 2 integrin; CD18; Cardiac development; Epithelial-mesenchymal transformation; Down syndrome; Mouse and chicken cardiogenesis.
Ano: 2010
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000100005

Single-walled carbon nanotubes functionalized with sodium hyaluronate enhance bone mineralization
Provedor de dados: 56
Autores: Sá,M.A.; Ribeiro,H.J.; Valverde,T.M.; Sousa,B.R.; Martins-Júnior,P.A.; Mendes,R.M.; Ladeira,L.O.; Resende,R.R.; Kitten,G.T.; Ferreira,A.J.
The aim of this study was to evaluate the effects of sodium hyaluronate (HY), single-walled carbon nanotubes (SWCNTs) and HY-functionalized SWCNTs (HY-SWCNTs) on the behavior of primary osteoblasts, as well as to investigate the deposition of inorganic crystals on titanium surfaces coated with these biocomposites. Primary osteoblasts were obtained from the calvarial bones of male newborn Wistar rats (5 rats for each cell extraction). We assessed cell viability using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide assay and by double-staining with propidium iodide and Hoechst. We also assessed the formation of mineralized bone nodules by von Kossa staining, the mRNA expression of bone repair proteins, and the deposition of inorganic...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Osteoblast; Nanotechnology; Carbon nanotubes; Sodium hyaluronate; Tissue engineering; Osseointegration.
Ano: 2016
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000200602