Consulta: creatorFacets:"Lebouvier, Nicolas"
Registros recuperados: 6
Data/hora: 06/06/2024 14:18:41

The Wound Healing and Antibacterial Activity of Five Ethnomedical Calophyllum inophyllum Oils: An Alternative Therapeutic Strategy to Treat Infected Wounds
Provedor de dados: 5
Autores: Leguillier, Teddy; Lecso-bornet, Marylin; Lemus, Christelle; Rousseau-ralliard, Delphine; Lebouvier, Nicolas; Hnawia, Edouard; Nour, Mohammed; Aalbersberg, William; Ghazi, Kamelia; Raharivelomanana, Phila; Rat, Patrice.
Background Calophyllum inophyllum L. (Calophyllaceae) is an evergreen tree ethno-medically used along the seashores and islands of the Indian and Pacific Oceans, especially in Polynesia. Oil extracted from the seeds is traditionally used topically to treat a wide range of skin injuries from burn, scar and infected wounds to skin diseases such as dermatosis, urticaria and eczema. However, very few scientific studies reported and quantified the therapeutic properties of Calophyllum inophyllum oil (CIO). In this work, five CIO from Indonesia (CIO1), Tahiti (CIO2, 3), Fiji islands (CIO4) and New Caledonia (CIO5) were studied and their cytotoxic, wound healing, and antibacterial properties were presented in order to provide a scientific support to their...
Tipo: Text
Ano: 2015
URL: https://archimer.ifremer.fr/doc/00667/77934/80119.pdf

Chemotaxonomy and cytotoxicity of the liverwort  Porella Viridissima
Provedor de dados: 5
Autores: Métoyer, Benjamin; Lebouvier, Nicolas; Hnawia, Edouard; Thouvenot, Louis; Wang, Fengrui; Harinantenaina Rakotondraibe, Liva; Raharivelomanana, Phila; Asakawa, Yoshinori; Nour, Mohammed.
The first chemotaxonomic study based on volatile components of Porella viridissima (Mitt.) Grolle is reported. The GC-MS analysis of ether extract was performed; ten santalane and five pinguisane-type sesquiterpenes were identified together with perrottetianal A as major diterpene. Most of detected santalane-type sesquiterpenes are reported for the first time in liverwort. P. viridissima was found to belong to the chemotype III (pinguisane/sacculatane) and shared chemical similarities with P. navicularis. Perrotettianal A was isolated and has shown strong cytotoxicity against ovarian cancer.
Tipo: Text
Palavras-chave: Liverwort; Porella viridissima; Chemotype; Pinguisane; Sacculatane; Ovarian cancer.
Ano: 2019
URL: https://archimer.ifremer.fr/doc/00660/77195/78611.pdf

Impact of Light Intensity on Antioxidant Activity of Tropical Microalgae
Provedor de dados: 5
Autores: Coulombier, Noémie; Nicolau, Elodie; Le Déan, Loic; Antheaume, Cyril; Jauffrais, Thierry; Lebouvier, Nicolas.
Twelve microalgae species isolated in tropical lagoons of New Caledonia were screened as a new source of antioxidants. Microalgae were cultivated at two light intensities to investigate their influence on antioxidant capacity. To assess antioxidant property of microalgae extracts, four assays with different modes of action were used: 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2’-azinobis (3-éthylbenzothiazoline-6-sulphonique) (ABTS), oxygen radical absorbance capacity (ORAC), and thiobabituric acid reactive substances (TBARS). This screening was coupled to pigment analysis to link antioxidant activity and carotenoid content. The results showed that none of the microalgae studied can scavenge DPPH and ABTS radicals, but Chaetoceros sp., Nephroselmis sp., and...
Tipo: Text
Palavras-chave: Nephroselmis; Light intensity; In vitro antioxidant activity; Siphonaxanthin; Carotenoid; Bioactive compounds.
Ano: 2020
URL: https://archimer.ifremer.fr/doc/00609/72152/70900.pdf

Chemotypes and Biomarkers of Seven Species of New Caledonian Liverworts from the Bazzanioideae Subfamily
Provedor de dados: 5
Autores: Metoyer, Benjamin; Lebouvier, Nicolas; Hnawia, Edouard; Herbette, Gaetan; Thouvenot, Louis; Asakawa, Yoshinori; Nour, Mohammed; Raharivelomanana, Phila.
Volatile components of seven species of the Bazzanioideae sub-family (Lepidoziaceae) native to New Caledonia, including three endemic species (Bazzania marginata, Acromastigum caledonicum and A. tenax), were analyzed by GC-FID-MS in order to index these plants to known or new chemotypes. Detected volatile constituents in studied species were constituted mainly by sesquiterpene, as well as diterpene compounds. All so-established compositions cannot successfully index some of them to known chemotypes but afforded the discovery of new chemotypes such as cuparane/fusicoccane. The major component of B. francana was isolated and characterized as a new zierane-type sesquiterpene called ziera-12(13), 10(14)-dien-5-ol (23). In addition, qualitative intraspecies...
Tipo: Text
Palavras-chave: Liverwort; Bazzania; Acromastigum; Sesquiterpene; Diterpene; Bis(bibenzyl); Biosynthesis; Zierane; Vittatin.
Ano: 2018
URL: https://archimer.ifremer.fr/doc/00660/77222/78670.pdf

Effects of Nitrogen Availability on the Antioxidant Activity and Carotenoid Content of the Microalgae Nephroselmis sp
Provedor de dados: 5
Autores: Coulombier, Noémie; Nicolau, Elodie; Le Déan, Loic; Barthelemy, Vanille; Schreiber, Nathalie; Brun, Pierre; Lebouvier, Nicolas; Jauffrais, Thierry.
Nephroselmis sp. was previously identified as a species of interest for its antioxidant properties owing to its high carotenoid content. In addition, nitrogen availability can impact biomass and specific metabolites’ production of microalgae. To optimize parameters of antioxidant production, Nephroselmis sp. was cultivated in batch and continuous culture conditions in stirred closed photobioreactors under different nitrogen conditions (N-repletion, N-limitation, and N-starvation). The aim was to determine the influence of nitrogen availability on the peroxyl radical scavenging activity (oxygen radical absorbance capacity (ORAC) assay) and carotenoid content of Nephroselmis sp. Pigment analysis revealed a specific and unusual photosynthetic system with...
Tipo: Text
Palavras-chave: Lutein; Natural products; Nutrients; Peroxyl radical; Siphonaxanthin.
Ano: 2020
URL: https://archimer.ifremer.fr/doc/00645/75699/76604.pdf

Chemodiversity of Calophyllum inophyllum L. oil bioactive components related to their specific geographical distribution in the South Pacific region
Provedor de dados: 5
Autores: Ginigini, Joape; Lecellier, Gael J.; Nicolas, Mael; Nour, Mohammed; Hnawia, Edouard; Lebouvier, Nicolas; Herbette, Gaetan; Lockhart, Peter; Raharivelomanana, Phila.
Background: Different parts of the tree Calophyllum inophyllum L. (nuts, leaves, roots, bark, fruits, nut oil and resin) are used as traditional medicines and cosmetics in most of the Pacific Islands. The oil efficiency as a natural cure and in traditional cosmetics has been largely described throughout the South Pacific, which led us to investigate C. inophyllum's chemical and genetic diversity. A correlative study of the nut resin and leaf DNA from three distinct archipelagos in the South Pacific was carried out in order to identify diversity patterns in C. inophyllum across the South Pacific. Methods: Calophyllum inophyllum plants were sampled from French Polynesia, New Caledonia and Fiji. We extracted tamanu oil (nut oil) resin for chemo-diversity...
Tipo: Text
Palavras-chave: Calophyllum inophyllum; Chemodiversity; South Pacific; Neoflavonoids; Oil; Biodiversity.
Ano: 2019
URL: https://archimer.ifremer.fr/doc/00659/77126/78506.pdf