Consulta: creatorFacets:"Lima,Elizabeth O. Cirne"
Registros recuperados: 1
Data/hora: 10/06/2024 18:00:16

An effective device for generating alginate microcapsules
Provedor de dados: 74
Autores: Bressel,Tatiana A.B.; Paz,Ana Helena; Baldo,Guilherme; Lima,Elizabeth O. Cirne; Matte,Ursula; Saraiva-Pereira,Maria Luiza.
An alternative approach to somatic gene therapy is to deliver the therapeutic protein by implanting genetically modified cells that could overexpress the gene of interest. Microencapsulation devices were designed to protect cells from host rejection and prevent the foreign cells from spreading while allowing protein secretion. Alginate microcapsules form a semi-permeable structure that is suitable for in vivo injection. In this study, we report an effective laboratory protocol for producing calcium alginate microcapsules, following optimization of uniformly shaped and sized particles containing viable cells. Encapsulation of baby hamster kidney (BHK) cells in alginate microcapsules was performed using a simple device consisting of a cylinder of compressed...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Alginate; Beads controlled release drug delivery microcapsules.
Ano: 2008
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572008000100023