Consulta: creatorFacets:"Lima,Gláucia Manoella de Souza"
Registros recuperados: 2
Data/hora: 12/06/2024 16:24:39

Screening of wild type Streptomyces isolates able to overproduce clavulanic acid
Provedor de dados: 58
Autores: Marques,Daniela A. Viana; Santos-Ebinuma,Valéria de Carvalho; Oliveira,Patrícia Maria Sobral de; Lima,Gláucia Manoella de Souza; Araújo,Janete M.; Lima-Filho,José L.; Converti,Attilio; Pessoa-Júnior,Adalberto; Porto,Ana L.F.
The selection of new microorganisms able to produce antimicrobial compounds is hoped for to reduce their production costs and the side effects caused by synthetic drugs. Clavulanic acid is a β-lactam antibiotic produced by submerged culture, which is widely used in medicine as a powerful inhibitor of β-lactamases, enzymes produced by bacteria resistant to antibiotics such penicillin and cephalosporin. The purpose of this work was to select the best clavulanic acid producer among strains of Streptomyces belonging to the Microorganism Collection of the Department of Antibiotics of the Federal University of Pernambuco (DAUFPE). Initially, the strains were studied for their capacity to inhibit the action of β-lactamases produced by Klebsiella aerogenes ATCC...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Clavulanic acid; Β-lactamases inhibitor; Streptomyces screening; Submerged culture; Growth kinetics.
Ano: 2014
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000300022

Screening of endophytic fungi stored in a culture collection for taxol production
Provedor de dados: 58
Autores: Andrade,Hortência Farias de; Araújo,Lívia Caroline Alexandre de; Santos,Bruno Souza dos; Paiva,Patrícia Maria Guedes; Napoleão,Thiago Henrique; Correia,Maria Tereza dos Santos; Oliveira,Maria Betânia Melo de; Lima,Gláucia Manoella de Souza; Ximenes,Rafael Matos; Silva,Túlio Diego da; Silva,Girliane Regina da; Silva,Márcia Vanusa da.
Abstract In this work, four isolates of endophytic fungi (Alternaria alternata, Colletotrichum gloesporioides, Glomerella cingulata and Nigrospora sphaerica), deposited in the culture collection ‘University Recife Mycologia’ (URM) at the Universidade Federal de Pernambuco, were characterized for the genes ITS 1 and 4 (region 5.8 S) and evaluated for taxol production.
Tipo: Info:eu-repo/semantics/other
Palavras-chave: Paclitaxel; Taxol route genes; ITS; Colletotrichum gloesporioides.
Ano: 2018
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822018000500059