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In vitro antifungal activity of Myracrodruon urundeuva Allemão against human vaginal Candida species
Provedor de dados: 42
Autores: OLIVEIRA,FERNANDO A. DE; RORATO,VANESSA C.; ALMEIDA-APOLONIO,ADRIANA A.; RODRIGUES,ALLAN B.; BARROS,ALINE L. DE; SANGALLI,ANDRÉIA; ARENA,ARIELLE C.; MOTA,JONAS S.; GRISOLIA,ALEXÉIA B.; OLIVEIRA,KELLY M.P. DE.
ABSTRACT Myracrodruon urundeuva is a plant native to Brazil, which is used by the indigenous population for the treatment of candidiasis. The aims of this study were to evaluate the antifungal activity of extract against human vaginal Candida species and evaluate the possible toxicological activities of M. urundeuva. Initially, ethanol extracts, ethyl acetate fractions, and hydroalcoholic fractions of the bark and leaf of M. urundeuva were used to determine the minimum inhibitory concentration. The extracts that showed antifungal activity were characterized by liquid chromatography and subjected to toxicity assessment. Toxic, cytotoxic, genotoxic, and mutagenic testing were performed using Allium cepa and Ames assays with the ethanol extracts of the bark...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Anacardiaceae; Candidiasis; Myracrodruon urundeuva; Traditional medicine.
Ano: 2017
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000502423