Consulta: creatorFacets:"Olicard, Cecile"
Registros recuperados: 3
Data/hora: 07/06/2024 00:55:08

In vitro research of anti-HSV-1 activity in different extracts from Pacific oysters Crassostrea gigas
Provedor de dados: 5
Autores: Olicard, Cecile; Didier, Yohann; Marty, Christel; Bourgougnon, Nathalie; Renault, Tristan.
Mortalities related to the detection of Ostreid Herpesvirus 1 (OsHV-1) have been previously reported in France among larvae and spat of the Pacific oyster Crassostrea gigas. Adult oysters appear less sensitive to herpesvirus infections, although OsHV-1 has been detected in adults without signs of disease or mortality. This suggests that the virus is able to persist in its host and that adult oysters may be able to control OsHV-1 infection. Little is known about antiviral substances in invertebrates. The present work concerns the research of antiviral substances in adult oyster C. gigas, where putative antiviral activities were monitored using 3 strategies: (1) in metabolites with variable polarity, (2) in peptidic extracts and (3) in crude haemolymph. In...
Tipo: Text
Palavras-chave: Haemolymph; Antiviral peptides; HSV 1; OsHV 1; Antiviral defence; Crassostrea gigas; Oyster.
Ano: 2005
URL: http://archimer.ifremer.fr/doc/2005/publication-2922.pdf

Etude des mécanismes antiviraux développés par les huîtres lors d'infections à virus de type herpès
Provedor de dados: 5
Autores: Olicard, Cecile.
Tipo: Text
Palavras-chave: Cytometry; Herpes like virus; Oyster; Antivirus mechanisms.
Ano: 2002
URL: http://archimer.ifremer.fr/doc/2002/rapport-1769.pdf

Putative antiviral activity in hemolymph from adult Pacific oysters, Crassostrea gigas
Provedor de dados: 5
Autores: Olicard, Cecile; Renault, Tristan; Torhy, Corinne; Benmansour, Abdenour; Bourgougnon, Nathalie.
Innate, non-specific resistance mechanisms are important to pathogens, particularly for delaying virus replication at the onset of infection, Innate immunity constitutes the first line of defense in vertebrates and is the only one in invertebrates. Little is known about possible antiviral substances in invertebrates. The present work concerns a Study of antiviral substances in hemolymph from adult Crassostrea gigas oysters. Despite the detection of cytotoxicity in fresh filtered hemolymph for both mammalian (CC50: 750 mu g/ml) and fish cells (CC50: &gt; 2000 mu g/ml for EPC cells and 345 mu g/ml for RTG-2 cells), an antiviral substance was detected. Fresh filtered hemolymph was capable of inhibiting the replication of herpes simplex virus type I in vitro...
Tipo: Text
Palavras-chave: Hemolymph; VHSV; IPNV; HSV; Antiviral defense; Crassosirea gigas; Oyster.
Ano: 2005
URL: http://archimer.ifremer.fr/doc/2005/publication-774.pdf