Consulta: creatorFacets:"Pichon, Anaïk"
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Data/hora: 11/06/2024 04:16:14

Environmental concentrations of benz[a]anthracene induce developmental defects and DNA damage and impair photomotor response in Japanese medaka larvae
Provedor de dados: 5
Autores: Le Bihanic, Florane; Sommard, Vivien; De Lansalut, Perrine; Pichon, Anaïk; Grasset, Julie; Berrada, Saadia; Budzinski, Helene; Cousin, Xavier; Morin, Benedicte; Cachot, Jerome.
Benz[a]anthracene (BaA) is a ubiquitous polycyclic aromatic hydrocarbon found in numerous aquatic ecosystems. However, ecotoxicological data in aquatic organisms are scarce. To remedy this lack of data, Japanese medaka (Oryzias latipes) embryos were exposed to BaA and toxic effects were investigated at multiple toxicological endpoints. Japanese medaka embryos were incubated onto BaA-spiked artificial sediment for 9 days at low or moderate environmental concentrations ranging from 0.9 to 12 µg g−1 dw. BaA-exposed embryos exhibited significant tachycardia. BaA exposure was also shown to increase CYP1A activity in the hepato-biliary tissue as well as craniofacial deformities and DNA damage in pro-larvae. The photomotor response of BaA-exposed larvae was...
Tipo: Text
Palavras-chave: Benz[a]anthracene; Spiked sediment; Teratogenicity; DNA damage; Swimming behavior; In vivo EROD activity.
Ano: 2015
URL: https://archimer.ifremer.fr/doc/00244/35513/34729.pdf