Consulta: creatorFacets:"Sánchez, Jorge"
Registros recuperados: 2
Data/hora: 13/06/2024 04:23:12

Patterns of distribution, population genetics and ecological requirements of field-occurring resistant and susceptible Pseudosuccinea columella snails to Fasciola hepatica in Cuba
Provedor de dados: 5
Autores: Alba, Annia; Vázquez, Antonio A.; Sánchez, Jorge; Lounnas, Manon; Pointier, Jean-pierre; Hurtrez-boussès, Sylvie; Gourbal, Benjamin.
Pseudosuccinea columella snails transmit the trematode Fasciola hepatica, but in Cuba, six naturally occurring populations successfully resist parasite infection. Here, we present an updated distribution of P. columella in Cuba; 68 positive sites with the earliest records more abundant in west-central Cuba and with east-central populations generally corresponding to the newest samples. No records were found farther east. The IPA site reported 10.5% prevalence of F. hepatica-infected snails. Population genetics, studied through microsatellites, showed low allelic and multilocus genotypic richness (MLGT), mainly in susceptible populations, strong deviations from panmixia and high self-fertilization rates. Susceptible individuals were grouped in one major...
Tipo: Text
Ano: 2019
URL: https://archimer.ifremer.fr/doc/00584/69660/67514.pdf

Natural resistance to Fasciola hepatica (Trematoda) in Pseudosuccinea columella snails: A review from literature and insights from comparative “omic” analyses
Provedor de dados: 5
Autores: Alba, Annia; Tetreau, Guillaume; Chaparro, Cristian; Sánchez, Jorge; Vázquez, Antonio A.; Gourbal, Benjamin.
The snail Pseudosuccinea columella is one of the main vectors of the medically-important trematode Fasciola hepatica. In Cuba, the existence of natural P. columella populations that are either susceptible or resistant to F. hepatica infection offers a unique snail-parasite for study of parasite-host compatibility and immune function in gastropods. Here, we review all previous literature on this system and present new “omic” data that provide a molecular baseline of both P. columella phenotypes from naïve snails. Comparison of whole snail transcriptomes (RNAseq) and the proteomes of the albumen gland (2D-electrophoresis, MS) revealed that resistant and susceptible strains differed mainly in an enrichment of particular biological processes/functions and a...
Tipo: Text
Palavras-chave: Transcriptome; Albumen gland; Allocation of resources; Response to stress; Immune defense; Cost of resistance.
Ano: 2019
URL: https://archimer.ifremer.fr/doc/00509/62039/66180.pdf