Consulta: creatorFacets:"Silveira,E.A."
Registros recuperados: 3
Data/hora: 03/06/2024 09:40:13

Efeito clínico do uso do parecoxib em modelo de sinovite induzida em pôneis
Provedor de dados: 45
Autores: Pozzobon,R.; Brass,K.E.; De La Corte,F.D.; Silveira,E.A.; Abreu,H.C.
Um modelo experimental de sinovite em pôneis foi usado para avaliar o efeito do parecoxib, um antiinflamatório não-esteroidal (AINE) seletivo injetável. Cinco dias após indução da sinovite, três pôneis foram tratados com 0,55mg/kg/dia (IV) de parecoxib e três receberam solução salina 0,9% (IV) por cinco dias. A avaliação de parâmetros clínicos dos animais e físico-químicos do líquido sinovial foi realizada antes da indução de sinovite, antes e 12, 24, 48, 72, 96 e 120 horas após o início do tratamento. A injeção intra-articular com adjuvante completo de Freund induziu sinovite de intensidade moderada a grave. Os pôneis tratados com parecoxib apresentaram diminuição do grau de claudicação; manutenção da flexão articular, do comprimento do passo, da...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Eqüino; Sinovite; Antiinflamatório não-esteroidal (AINE); Parecoxib.
Ano: 2008
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352008000400005

A single resistance exercise session improves myocardial contractility in spontaneously hypertensive rats
Provedor de dados: 56
Autores: Fernandes,A.A.; Faria,T. de O.; Ribeiro Júnior,R.F.; Costa,G.P.; Marchezini,B.; Silveira,E.A.; Angeli,J.K.; Stefanon,I.; Vassallo,D.V.; Lizardo,J.H.
Resistance training evokes myocardial adaptation; however, the effects of a single resistance exercise session on cardiac performance are poorly understood or investigated. This study aimed to investigate the effects of a single resistance exercise session on the myocardial contractility of spontaneously hypertensive rats (SHRs). Male 3-month-old SHRs were divided into two groups: control (Ct) and exercise (Ex). Control animals were submitted to sham exercise. Blood pressure was measured in conscious rats before the exercise session to confirm the presence of arterial hypertension. Ten minutes after the exercise session, the animals were anesthetized and killed, and the hearts were removed. Cardiac contractility was evaluated in the whole heart by the...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Cardiac; Contractility; Myocardium; Proteins; Resistance exercise.
Ano: 2015
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000900813

Acute lead-induced vasoconstriction in the vascular beds of isolated perfused rat tails is endothelium-dependent
Provedor de dados: 56
Autores: Silveira,E.A.; Lizardo,J.H.F.; Souza,L.P.; Stefanon,I.; Vassallo,D.V.
Chronic lead exposure induces hypertension in humans and animals, affecting endothelial function. However, studies concerning acute cardiovascular effects are lacking. We investigated the effects of acute administration of a high concentration of lead acetate (100 µΜ) on the pressor response to phenylephrine (PHE) in the tail vascular bed of male Wistar rats. Animals were anesthetized with sodium pentobarbital and heparinized. The tail artery was dissected and cannulated for drug infusion and mean perfusion pressure measurements. Endothelium and vascular smooth muscle relaxation were tested with acetylcholine (5 µg/100 µL) and sodium nitroprusside (0.1 µg/100 µL), respectively, in arteries precontracted with 0.1 µM PHE. Concentration-response curves to PHE...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Lead acetate; Vascular reactivity; Endothelium; Hypertension.
Ano: 2010
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000500011