Consulta: creatorFacets:"Zago,Marco A."
Registros recuperados: 2
Data/hora: 01/06/2024 01:28:32

Heterogeneous ethnic distribution of the factor v leiden mutation
Provedor de dados: 74
Autores: Franco,Rendrik F.; Elion,Jacques; Santos,Sidney E.B.; Araújo,Amélia G.; Tavella,Marli H.; Zago,Marco A.
Inherited resistance to activated protein C caused by the factor V Leiden (FVL) mutation is the most common genetic cause of venous thrombosis yet described, being found in 20-60% of patients with venous thrombophilia. A relationship between the FVL mutation and an increased predisposition to arterial thrombosis in young women was recently reported. We assessed the prevalence of the FVL mutation in 440 individuals (880 chromosomes) belonging to four different ethnic groups: Caucasians, African Blacks, Asians and Amerindians. PCR amplification followed by MnlI digestion was employed to define the genotype. The FVL mutation was found in a heterozygous state in four out of 152 Whites (2.6%), one out of 151 Amerindians (0.6%), and was absent among 97 African...
Tipo: Info:eu-repo/semantics/article
Ano: 1999
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47571999000200001

Absence of the E2 allele of apolipoprotein in Amerindians
Provedor de dados: 54
Autores: Marin,Guilherme B.; Tavella,Marli H.; Guerreiro,João F.; Santos,Sidney E.B.; Zago,Marco A.
Determination of the ApoE allele distribution in five South American Amerindian tribes revealed absence of the ApoE2 allele, accompanied by high ApoE3 and low ApoE4 allele frequencies for most tribes, a distribution only previously reported for the Inuit Eskimo from Greenland.
Tipo: Info:eu-repo/semantics/other
Ano: 1997
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-84551997000400029