Consulta: creatorFacets:"Zubair,Muhammad"
Registros recuperados: 2
Data/hora: 06/06/2024 05:36:51

Compositional studies and Biological activities of Perovskia abrotanoides Kar. oils
Provedor de dados: 48
Autores: Ashraf,Sadaf Naz; Zubair,Muhammad; Rizwan,Komal; Tareen,Rasool Bakhsh; Rasool,Nasir; Zia-Ul-Haq,Muhammad; Ercisli,Sezai.
BACKGROUND: Current study has been designed to evaluate the chemical composition of essential and fixed oils from stem and leaves of Perovskia abrotanoides and antioxidant and antimicrobial activities of these oils. RESULTS: GC-MS analysis of essential oil identified 19 compounds with (E)-9-dodecenal being the major component in stem and hexadecanoic acid in leaves. In contrast, GC-MS analysis of fixed oil showed 40 constituents with &amp;#945;-amyrin the major component in stem and &amp;#945;-copaene in leaves. The antioxidant activity showed the highest value of 76.7% in essential oil from leaves in comparison with fixed oil from stem (45.9%) through inhibition of peroxidation in linoleic acid system. The antimicrobial assay tested on different...
Tipo: Journal article
Palavras-chave: Perovskia abrotanoides; Essential oil; Fixed oil; Antioxidant capacity; Antimicrobial activity.
Ano: 2014
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100012

Stability indicating RP-HPLC method for simultaneous determination of gatifloxacin and dexamethasone in binary combination
Provedor de dados: 60
Autores: Razzaq,Syed Naeem; Ashfaq,Muhammad; Khan,Islam Ullah; Mariam,Irfana; Razzaq,Syed Saleem; Mustafa,Ghulam; Zubair,Muhammad.
Abstract In this study, conditions were optimized for development of a simple RP-HPLC method for simultaneous analysis of gatifloxacin and dexamethasone in different matrices like pharmaceuticals, human serum and urine. Good separation of gatifloxacin and dexamethasone from the induced degradation products was accomplished using C8 as stationary phase; 0.02 M phosphate buffer (pH 3.0) and methanol (42:58 v/v) as mobile phase. The concentration was measured with DAD at 270 nm. Linearity was observed in the range of 0.000040-0.000280 mol/L for gatifloxacin (r2≥0.999) and 0.000013-0.000091 mol/L for dexamethasone (r2≥0.999). Both the analyte peaks were completely separated from the peaks of induced degradation products as indicated by the peak purity index...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Gatifloxacin; Dexamethasone; High performance liquid chromatography; Validation; Plasma; Degradation products.
Ano: 2017
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000100607