Consulta: subjectFacets:"Acetylsalicylic Acid"
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Data/hora: 05/06/2024 11:30:59

Acetylsalicylic acid and morphology of red blood cells
Provedor de dados: 52
Autores: Frydman,Jacques Natan Grinapel; Fonseca,Adenilson de Souza da; Rocha,Vanessa Câmara da; Benarroz,Monica Oliveira; Rocha,Gabrielle de Souza; Pereira,Marcia de Oliveira; Pereira,Mario José; Medeiros,Aldo Cunha; Bernardo-Filho,Mario.
This work evaluated the effect of in vitro and in vivo treatment with ASA on the morphology of the red blood cells. Blood samples or Wistar rats were treated with ASA for one hour. Blood samples or animals treated with saline were used as control group. Blood smears were prepared, fixed, stained and the qualitative and quantitative morphology of red blood cells were evaluated under optical microscopy. Data showed that the in vitro treatment for one hour with ASA at higher dose used significantly (p&lt;0.05) modified the perimeter/area ratio of the red blood cells. No morphological alterations were obtained with the in vivo treatment. ASA use at highest doses could interfere on shape of red blood cells.
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Acetylsalicylic Acid; Blood Cells; Morphology.
Ano: 2010
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132010000300010

Acetylsalicylic acid and labeling of blood constituents with technetium-99m
Provedor de dados: 52
Autores: Fonseca,Adenilson de Souza da; Frydman,Jacques Natan Grinapel; Rocha,Vanessa Câmara da; Bernardo-Filho,Mario.
Acetylsalicylic acid is the drug most used an anti-inflammatory agent and for secondary prevention of thrombotic phenomenon. Drugs can modify the labeling of blood constituents with technetium-99m (99mTc). The aim of this work was to evaluate the effect of in vitro or in vivo assays with acetylsalicylic acid on the labeling of the blood constituents with 99mTc. In vitro assay was performed with samples of whole blood from Wistar rats incubated with acetylsalicylic acid (1.0 mg/ml) for one hour before the 99mTc-labeling process. For in vivo assay, Wistar rats were treated with acetylsalicylic acid (1.5 mg/kg) during one hour, and the whole blood was withdrawn for the 99mTc-labeling process. Saline was used in control groups. Data showed that the fixation of...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Acetylsalicylic Acid; Blood Constituents; Technetium-99m.
Ano: 2005
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000700024