Consulta: subjectFacets:"Additive toxicity"
Registros recuperados: 1
Data/hora: 09/06/2024 13:31:11

Challenges in Regulating Pesticide Mixtures
Provedor de dados: 7
Autores: Lydy, Michael; Southern Illinois University at Carbondale; mlydy@siu.edu; Belden, Jason; Southern Illinois University at Carbondale; jbelden@siu.edu; Wheelock, Craig; University of California at Davis; cewheelock@ucdavis.edu; Hammock, Bruce; University of California at Davis; bdhammock@ucdavis.edu; Denton, Debra; U.S. Environmental Protection Agency; Denton.Debra@epamail.epa.gov.
This paper introduces the field of mixture toxicity and the challenges in regulating pesticide mixtures. Even though pesticides are unique chemical stressors designed to have biological activity that can affect a number of nontarget species, they are intentionally placed into the environment in large quantities. Currently, methods and terminology for evaluating mixture toxicity are poorly established. The most common approach used is the assumption of additive concentration, with the concentrations adjusted for potency to a reference toxicant. Using this approach, the joint action of pesticides that have similar chemical structures and modes of toxic action can be predicted. However, this approach and other modeling techniques often provide little insight...
Tipo: Peer-Reviewed Reports
Palavras-chave: EPA; Additive toxicity; Concentration addition; Independent action; Mixtures; Pesticides; Regulations; Risk cup; Toxicity; Toxicity assessment.
Ano: 2004