Consulta: subjectFacets:"Biomphalaria glabrata"
Registros recuperados: 10
Data/hora: 06/06/2024 08:24:33

Atividade moluscicida de princípios ativos de folhas de Lycopersicon esculentum (Solanales, Solanaceae) em Biomphalaria glabrata (Gastropoda, Planorbidae)
Provedor de dados: 76
Autores: Leyton,Vilma; Henderson,Thomas O.; Mascara,Douglas; Kawano,Toshie.
Foram obtidos extratos aquosos e alcoólicos a partir de pó de folhas secas de tomateiro (Lycopersicon esculentum, Mill.) c.v. Cereja. Por extração metanólica e precipitação alcalina, foi obtido um produto que denominamos "glicoalcalóide esteroidal bruto" (GEb), no qual foi caracterizada a presença de tomatina. Em ensaios laboratoriais, os extratos aquosos, alcoólicos e o GEb apresentaram atividade moluscicida em Biomphalaria glabrata (Say, 1818). O "glicoalcalóide esteroidal bruto" apresentou alta atividade moluscicida (CL50 = 8,01 ppm e CL90 = 13,17 ppm), comparável à atividade da tomatina. Desovas de B. glabrata mostraram-se resistentes aos extratos testados. Os níveis de atividade moluscicida apresentados pelos diversos extratos e o GEb, apontam apenas...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Moluscicida; Biomphalaria glabrata; Lycopersicon esculentum; Tomateiro.
Ano: 2005
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0073-47212005000200012

BgTEP: An Antiprotease Involved in Innate Immune Sensing in Biomphalaria glabrata
Provedor de dados: 5
Autores: Portet, Anais; Galinier, Richard; Pinaud, Silvain; Portela, Julien; Nowacki, Fanny; Gourbal, Benjamin; Duval, David.
Insect thioester-containing protein (iTEP) is the most recently defined group among the thioester-containing protein (TEP) superfamily. TEPs are key components of the immune system, and iTEPs from flies and mosquitoes were shown to be major immune weapons. Initially characterized from insects, TEP genes homologous to iTEP were further described from several other invertebrates including arthropods, cniderians, and mollusks albeit with few functional characterizations. In the freshwater snail Biomphalaria glabrata, a vector of the schistosomiasis disease, the presence of a TEP protein (BgTEP) was previously described in a well-defined immune complex involving snail lectins (fibrinogen-related proteins) and schistosome parasite mucins (SmPoMuc). To...
Tipo: Text
Palavras-chave: Thioester-containing protein; Complement-like protein; Biomphalaria glabrata; Interaction host/pathogens; Innate immunity.
Ano: 2018
URL: https://archimer.ifremer.fr/doc/00444/55548/71780.tif

Advances in gastropod immunity from the study of the interaction between the snail Biomphalaria glabrata and its parasites: A review of research progress over the last decade
Provedor de dados: 5
Autores: Coustau, C.; Gourbal, B.; Duval, D.; Yoshino, T. P.; Adema, C. M.; Mitta, Guillaume.
This review summarizes the research progress made over the past decade in the field of gastropod immunity resulting from investigations of the interaction between the snail Biomphalaria glabrata and its trematode parasites. A combination of integrated approaches, including cellular, genetic and comparative molecular and proteomic approaches have revealed novel molecular components involved in mediating Biomphalaria immune responses that provide insights into the nature of host-parasite compatibility and the mechanisms involved in parasite recognition and killing. The current overview emphasizes that the interaction between B. glabrata and its trematode parasites involves a complex molecular crosstalk between numerous antigens, immune receptors, effectors...
Tipo: Text
Palavras-chave: Biomphalaria glabrata; Schistosoma mansoni; Echinostoma caproni; Immunity; Compatibility.
Ano: 2015
URL: https://archimer.ifremer.fr/doc/00276/38718/38622.pdf

Specific Pathogen Recognition by Multiple Innate Immune Sensors in an Invertebrate
Provedor de dados: 5
Autores: Tetreau, Guillaume; Pinaud, Silvain; Portet, Anais; Galinier, Richard; Gourbal, Benjamin; Duval, David.
Detection of pathogens by all living organisms is the primary step needed to implement a coherent and efficient immune response. This implies a mediation by different soluble and/or membrane-anchored proteins related to innate immune receptors called PRRs (pattern-recognition receptors) to trigger immune signaling pathways. In most invertebrates, their roles have been inferred by analogy to those already characterized in vertebrate homologs. Despite the induction of their gene expression upon challenge and the presence of structural domains associated with the detection of pathogen-associated molecular patterns in their sequence, their exact role in the induction of immune response and their binding capacity still remain to be demonstrated. To this...
Tipo: Text
Palavras-chave: Invertebrate innate immunity; Interactome; Pathogen sensing; Biomphalaria glabrata; Pattern-recognition receptor; Proteomic profiling; Immune specificity; Hemocyte-free hemolymph.
Ano: 2017
URL: https://archimer.ifremer.fr/doc/00405/51633/71796.pdf

Glabralysins, Potential New β-Pore-Forming Toxin Family Members from the Schistosomiasis Vector Snail Biomphalaria glabrata
Provedor de dados: 5
Autores: Lassalle, Damien; Tetreau, Guillaume; Pinaud, Silvain; Galinier, Richard; Crickmore, Neil; Gourbal, Benjamain; Duval, David.
Biomphalaria glabrata is a freshwater Planorbidae snail. In its environment, this mollusk faces numerous microorganisms or pathogens, and has developed sophisticated innate immune mechanisms to survive. The mechanisms of recognition are quite well understood in Biomphalaria glabrata, but immune effectors have been seldom described. In this study, we analyzed a new family of potential immune effectors and characterized five new genes that were named Glabralysins. The five Glabralysin genes showed different genomic structures and the high degree of amino acid identity between the Glabralysins, and the presence of the conserved ETX/MTX2 domain, support the hypothesis that they are pore-forming toxins. In addition, tertiary structure prediction confirms that...
Tipo: Text
Palavras-chave: Pore-forming toxin; Cry toxin; Invertebrate; Biomphalaria glabrata; Host; Pathogen; Vector snail; Innate immunity.
Ano: 2020
URL: https://archimer.ifremer.fr/doc/00601/71267/69655.pdf

A New Assessment of Thioester-Containing Proteins Diversity of the Freshwater Snail Biomphalaria glabrata
Provedor de dados: 5
Autores: Duval, David; Pichon, Rémi; Lassalle, Damien; Laffitte, Maud; Gourbal, Benjamain; Galinier, Richard.
Thioester-containing proteins (TEPs) superfamily is known to play important innate immune functions in a wide range of animal phyla. TEPs are involved in recognition, and in the direct or mediated killing of several invading organisms or pathogens. While several TEPs have been identified in many invertebrates, only one TEP (named BgTEP) has been previously characterized in the freshwater snail, Biomphalaria glabrata. As the presence of a single member of that family is particularly intriguing, transcriptomic data and the recently published genome were used to explore the presence of other BgTEP related genes in B. glabrata. Ten other TEP members have been reported and classified into different subfamilies: Three complement-like factors (BgC3-1 to BgC3-3),...
Tipo: Text
Palavras-chave: Biomphalaria glabrata; Thioester-containing protein; Alternative splicing; Immunity; Schistosome.
Ano: 2020
URL: https://archimer.ifremer.fr/doc/00601/71268/69657.pdf

Molluscicidal and parasiticidal activities of Eryngium triquetrum essential oil on Schistosoma mansoni and its intermediate snail host Biomphalaria glabrata, a double impact
Provedor de dados: 5
Autores: De Carvalho Augusto, Ronaldo; Merad, Nadjiya; Rognon, Anne; Gourbal, Benjamin; Bertrand, Cédric; Djabou, Nassim; Duval, David.
Background Freshwater snails are the intermediate hosts of a large variety of trematode flukes such as Schistosoma mansoni responsible for one of the most important parasitic diseases caused by helminths, affecting 67 million people worldwide. Recently, the WHO Global Vector Control Response 2017–2030 (GVCR) programme reinforced its message for safer molluscicides as part of required strategies to strengthen vector control worldwide. Here, we present the essential oil from Eryngium triquetrum as a powerful product with molluscicide and parasiticide effect against S. mansoni and the snail intermediate host Biomphalaria glabrata. Methods In the present study, we describe using several experimental approaches, the chemical composition of E. triquetrum...
Tipo: Text
Palavras-chave: Biomphalaria glabrata; Eryngium triquetrum; Molluscicide; Oil; Parasiticide; Schistosoma mansoni.
Ano: 2020
URL: https://archimer.ifremer.fr/doc/00652/76382/77391.pdf

Hemocyte siRNA uptake is increased by 5′ cholesterol-TEG addition in   Biomphalaria glabrata   , snail vector of schistosome
Provedor de dados: 5
Autores: Portet, Anaïs; Galinier, Richard; Lassalle, Damien; Faille, Alexandre; Gourbal, Benjamin; Duval, David.
Biomphalaria glabrata is one of the snail intermediate hosts of Schistosoma mansoni, the causative agent of intestinal schistosomiasis disease. Numerous molecular studies using comparative approaches between susceptible and resistant snails to S. mansoni infection have helped identify numerous snail key candidates supporting such susceptible/resistant status. The functional approach using RNA interference (RNAi) remains crucial to validate the function of such candidates. CRISPR-Cas systems are still under development in many laboratories, and RNA interference remains the best tool to study B. glabrata snail genetics. Herein, we describe the use of modified small interfering RNA (siRNA) molecules to enhance cell delivery, especially into hemocytes, the...
Tipo: Text
Palavras-chave: Biomphalaria glabrata; Cholesteryl TEG; RNAi interference; BgTEP1; Hemocyte.
Ano: 2021
URL: https://archimer.ifremer.fr/doc/00682/79376/81902.pdf

Aspectos histológicos das gônadas hermafroditas de Biomphalaria glabrata e Bradybaena similaris (Mollusca, Gastropoda, Pulmonata)
Provedor de dados: 84
Autores: Silva,Rinaldo Florêncio da; Cubas,Jairo José Matozinho; Moraes,Josué de.
Biomphalaria glabrata (Say, 1818) é um gastrópode pulmonado de água doce que desperta grande interesse médico e veterinário. Bradybaena similaris (Férussac, 1821) é um gastrópode pulmonado terrestre considerado uma praga agrícola de plantações de hortaliças. Ambas as espécies são hospedeiras intermediárias de helmintos. Esses moluscos possuem uma gônada hermafrodita produtora de óvulos e espermatozóides de forma simultânea. Neste estudo foram avaliados aspectos histomorfológicos das gônadas hermafroditas de B. glabrata e B. similaris. A gônada de B. similaris encontra-se subdividida em lobos com glândulas em seu interior, o que não foi observado em B. glabrata. Além disso, em B. similaris as células germinativas estão acumuladas em determinados pontos e...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Histologia; Gônada hermafrodita; Biomphalaria glabrata; Bradybaena similaris.
Ano: 2009
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0031-10492009003300001

Behavioral response of Biomphalaria glabrataexposed to a sublethal concentration of Euphorbia miliivar. hislopii latex
Provedor de dados: 42
Autores: ALBERTO-SILVA,ANNA CARLA; CUNHA,RODOLFO A.; COSTA,VALDIR A. DA; SANTOS,EVERTON GUSTAVO N. DOS; VASCONCELLOS,MAURÍCIO C. DE; MELLO-SILVA,CLÉLIA CHRISTINA; SANTOS,CLÁUDIA P.
Abstract  The Euphobia milii var. hislopii latex has been tested in the control of schistosomiasis but its action in the locomotor activity of Biomphalaria glabrata is unknown. The objective of this work was to study the locomotor and reproductive behaviors of B. glabrata exposed to E. milii var. hislopii latex. For this, 96 snails were individually exposed to the latex (LC50 - 0.53 mg / L) for 24 hours. The specimens were submitted to biomonitoring for image analysis to record the locomotor parameters at different times: before exposure (control), one day post exposure (group 1 d-p-e) and 30 days post exposure (group 30 d-p-e). The reproductive parameters were recorded weekly for 10 weeks. All locomotor activities of group 1 d-p-e decreased significantly....
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Behavior; Biomonitoring; Biomphalaria glabrata; Control of schistosomiasis; Euphorbia milii var.
Ano: 2020
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652020000100716