Consulta: subjectFacets:"Brown adipose tissue"
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Increase in skeletal muscle protein content by the ß-2 selective adrenergic agonist clenbuterol exacerbates hypoalbuminemia in rats fed a low-protein diet
Provedor de dados: 56
Autores: Sawaya,A.L.; Lunn,P.G.
This investigation examined how the nutritional status of rats fed a low-protein diet was affected when the animals were treated with the ß-2 selective agonist clenbuterol (CL). Males (4 weeks old) from an inbred, specific-pathogen-free strain of hooded rats maintained at the Dunn Nutritional Laboratory were used in the experiments (N = 6 rats per group). CL treatment (Ventipulmin, Boehringer-Ingelheim Ltd., 3.2 mg/kg diet for 2 weeks) caused an exacerbation of the symptoms associated with protein deficiency in rats. Plasma albumin concentrations, already low in rats fed a low-protein diet (group A), were further reduced in CL rats (A = 25.05 ± 0.31 vs CL = 23.64 ± 0.30 g/l, P&amp;lt;0.05). Total liver protein decreased below the level seen in either...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Protein-energy malnutrition; Rats; Clenbuterol; Hypoalbuminemia; Brown adipose tissue; SS-2 agonist.
Ano: 1998
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000600015