Consulta: subjectFacets:"Chimie sol-gel"
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Data/hora: 18/06/2024 00:48:18

Silanisation de polysaccharides en milieu liquide ionique et réactivité d’un organoalkoxysilane vis-à-vis de nucléophiles simples : vers des hydrogels injectables pour l’ingénierie tissulaire du cartilage
Provedor de dados: 5
Autores: Guillory, Xavier.
Tissue engineering is a real challenge for the treatment of cartilage pathologies. In this field, biomimetic hydrogels based on natural polymers are among the most commonly used matrices. A hydrogel made of silanized hydroxypropylmethylcellulose (HPMC-Si) is especially promising because it can be injected in cartilaginous lesions by minimally invasive surgery. However, the current synthesis of HPMC-Si is limited by the insolubility of hydroxypropylmethylcellulose (HPMC). This thesis work was focused on finding new synthesis conditions for the design of HPMC-Si hydrogel. In order to obtain a complete solubilization of HPMC and to improve its functionalization by the (3-glycidyloxypropyl) trimethoxysilane (GPTMS), the use of ionic liquids (IL), which are...
Tipo: Text
Palavras-chave: Silanisation; Biopolymères; Polysaccharides; Liquides ioniques; Chimie sol-gel; Ingénierie tissulaire; Hydrogels.; Silanization; Biopolymers; Polysaccharides; Ionic liquids; Sol-gel chemistry; Tissue engineering; Hydrogels.
Ano: 2016
URL: https://archimer.ifremer.fr/doc/00341/45188/44585.pdf