Consulta: subjectFacets:"Collagen remodeling"
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Data/hora: 01/06/2024 13:38:38

Remodeling in the ischemic heart: the stepwise progression for heart
Provedor de dados: 56
Autores: Stefanon,I.; dos Santos,L.; Baldo,M.P.
Abstract Coronary artery disease is the leading cause of death in the developed world and in developing countries. Acute mortality from acute myocardial infarction (MI) has decreased in the last decades. However, the incidence of heart failure (HF) in patients with healed infarcted areas is increasing. Therefore, HF prevention is a major challenge to the health system in order to reduce healthcare costs and to provide a better quality of life. Animal models of ischemia and infarction have been essential in providing precise information regarding cardiac remodeling. Several of these changes are maladaptive, and they progressively lead to ventricular dilatation and predispose to the development of arrhythmias, HF and death. These events depend on cell death...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Coronary occlusion; Inflammation; Collagen remodeling; Mechanical dysfunction; Heart failure; Rats.
Ano: 2011
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000900010