Consulta: subjectFacets:"Common variable immunodeficiency"
Registros recuperados: 3
Data/hora: 12/06/2024 11:55:35

Cutaneous cytomegalovirus infection in a child with hyper IgE and specific defects in antibody response to protein vaccines
Provedor de dados: 55
Autores: Fallah,Shahrzad; Tabatabaei,Ahmad; Pournasir,Zahra; Chavoshzadeh,Zahra; Rezaei,Nima.
Cytomegalovirus (CMV) infection is a common opportunistic systemic infection in immunocompromised patients, but skin involvement is rare. Herein, we report a 10 year-old girl from consanguineous parents who was referred to our center because of disseminated maculopapular rash. She had history of upper and lower respiratory tract infections. In immunological studies, increased serum IgE level and decreased responses to tetanus and diphtheria were detected. Polymerase chain reaction (PCR) examination of bronchoalveolar lavage and serum sample revealed the presence of CMV. Early diagnosis of cutaneous CMV and appropriate treatment are the key actions in management of patients with underlying immunodeficiencies to avoid further complications.
Tipo: Info:eu-repo/semantics/report
Palavras-chave: Cytomegalovirus infections; Antibody formation; Common variable immunodeficiency.
Ano: 2011
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000500013

A case study of disseminated histoplasmosis linked to common variable immunodeficiency
Provedor de dados: 55
Autores: Rachid,Acir; Rezende,Lucila Stange; Moura,Suzelle Freitas de; Loffy,Paulo C.; Magalhães,Francisco Luiz Gomide M.
Histoplasma capsulatum, a ground fungus, can infect humans, normally in endemic areas; the resulting disease can be asymptomatic or it can have a benign development, but in rare cases it can develop into a serious clinical condition and can even be fatal. Its most characteristic initial location is in the lungs, resembling tuberculosis, often accompanied by mediastinitis and an exuberant fibrotic response. The spread of this infection can be caused by the concomitance of another illness that alters the immunological balance. Sometimes such an association is not clear. Therefore, disseminated histoplasmosis is defined as a clinical condition where the fungus is present in more than one location. Common variable immunodeficiency is characterized by a...
Tipo: Info:eu-repo/semantics/report
Palavras-chave: Disseminated histoplasmosis; Common variable immunodeficiency; Immunoglobulins.
Ano: 2003
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000400007

Hypogammaglobulinemia: a diagnosis that must not be overlooked
Provedor de dados: 56
Autores: Pimenta,F.M.C.A.; Palma,S.M.U.; Constantino-Silva,R.N.; Grumach,A.S.
Humoral immunological defects are frequent and important causes of hypogammaglobulinemia, leading to recurrent infections, autoimmunity, allergies, and neoplasias. Usually, its onset occurs in childhood or during the second and third decades of life; however, the diagnosis is made, on average, 6 to 7 years afterwards. As a consequence, antibody defects can lead to sequelae. Here we describe the clinical-laboratory characteristics, treatment, and prognoses of patients with hypogammaglobulinemia. An observational, cross-sectional, and retrospective study of patients attending the recently established outpatient group of Clinical Immunology between 2013 and 2018 was carried out. Patients with IgG levels below 2 standard deviations from the mean values for the...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Primary immunodeficiency; Common variable immunodeficiency; Hypogammaglobulinemia; Chemotherapy; Antibody defects; Immunoglobulin therapy.
Ano: 2019
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019001000608