Consulta: subjectFacets:"Dépolymérisation enzymatique"
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Data/hora: 09/06/2024 13:39:20

Dérivés de l'exopolysaccharide d’Alteromonas infernus, mimétiques de glycosaminoglycanes, et développement d'une stratégie pour leur analyse structurale
Provedor de dados: 5
Autores: Akoumany, Katy.
In search of new bioactive compounds, marine bacteria constitute a considerable source of innovative molecules. The bacterial exopolysaccharide (EPS), produced by the deep-sea hydrothermal vent strain Alteromonas infernus, is a high-molecular-weight, highly branched and anionic heteropolysaccharide with a nonasaccharide repeating unit. This macromolecule and its low-molecular-weight derivatives obtained through a chemical process have previously displayed interesting GAG-like properties such as anti-metastatic and anti-coagulant (heparin-like) ones; they can also improve stem cell differentiation. To investigate the molecular bases of the biological activity and to facilitate the structural analysis of the bioactive derivatives (~20 000 g/mol), fragments...
Tipo: Text
Palavras-chave: Bactérie marine; Exopolysaccharides; Dépolymérisation enzymatique; Synthèse organique; Marine bacteria; Exopolysaccharides; Enzymatic depolymerisation; Organic synthesis.
Ano: 2019
URL: https://archimer.ifremer.fr/doc/00605/71733/70206.pdf