Consulta: subjectFacets:"ERK 1/2"
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Data/hora: 13/06/2024 00:50:00

Topical and intraluminal Carolina Rinse Solution in p44/42 and p38 MAP Kinase activation profile in rabbit jejunum after ischemia and reperfusion
Provedor de dados: 65
Autores: Brandstetter,Luciana Ramos Gaston; Araújo,Eugênio Gonçalves de; Moreno,Juan Carlos Duque; Fioravanti,Maria Clorinda Soares; Moura,Veridiana Maria Brianezi Dignani de; Machado,Patrícia de Almeida.
The effects of topical and intraluminal Carolina Rinse Solution (CRS) in p44/42 (ERK 1/2) and p38 MAPK activation profile, in rabbit jejunum after ischemia and reperfusion (I/R), were investigated in this study. Fifteen New Zealand rabbits were allocated in three groups: Sham-operated (A), Ischemia and reperfusion (B) and CRS (C). Groups B and C were subjected to one hour of ischemia and two hours of reperfusion. In group C, ten minutes prior to reperfusion, the bowel lumen was filled with CRS, and the segment was immersed in CRS until reperfusion onset. Ischemia and reperfusion stimulated the phosphorylation of the p44/42 MAPK and p38 MAPK pathways in some layers of jejunum. Progressive activation of p44/42 MAPK was chiefly localized in the crypts of...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: ERK 1/2; Intestine; Ischemia; P38; Reperfusion.
Ano: 2014
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782014000100014