Consulta: subjectFacets:"Eserine"
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Anticholinesterase effect of eserine (physostigmine) in fish and crustacean species
Provedor de dados: 52
Autores: Monserrat,José M.; Bianchini,Adalto.
The kinetic characteristic (Km) of cholinesterase from the crab Chasmagnathus granulata, the shrimp Farfantepenaeus paulensis and the fish Odontesthes bonaeriensis were compared and correlated with the anticholinesterasic effect of eserine (physostigmine). For the crustaceans, the estimated Km values were about 5-8 times higher than that estimated for the fish (0.04 mM). In the crab and the shrimp, the concentration of eserine which inhibited 50% of cholinesterase activity (IC50) was estimated as 5.33x10-4 and 4.33x10-4 mM, respectively. In both cases, it was significantly higher (P &lt; 0.05) than that estimated for the fish larvae (7.43x10-5 mM). A high Km could reflect a lower affinity of the cholinesterase for its natural substrate, acetylcholine, or...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Eserine; Physostigmine; Acetylcholinesterase; Fish; Silverside fish; Crustacean.
Ano: 2001
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132001000100009