Consulta: subjectFacets:"Flavonoids"
Registros recuperados: 91
Data/hora: 02/06/2024 10:54:25

Cinética del crecimiento, desarrollo floral y acumulación de flavonoides en caléndula
Provedor de dados: 32
Autores: Palma Tenango, Mariana.
Caléndula (Calendula officinalis L.) tiene múltiples usos ornamentales, medicinales, industriales e incluso alimenticios. El capitulo floral es rico en flavonoides, mismos que tienen actividad antiinflamatoria y antioxidante. Este trabajo tuvo como finalidad, medir la concentración de flavonoides totales expresados como quercetina en capítulos florales, flores liguladas y flores tubulares en diferentes etapas de floración en, analizar la cinética de crecimiento y análisis preliminar de terpenoides. La mayor concentración de flavonoides totales expresados como quercetina en el capítulo floral fue de 177.77  mg g-1 de materia seca, en flores liguladas fue de   114.91 mg g-1 de materia seca y en flores tubulares de 181.30 mg g-1 de materia seca. La planta...
Tipo: Tesis
Palavras-chave: Calendula officinalis L.; Capítulo floral; Flavonoides; Etapas de desarrollo floral; Cinética de crecimiento; Maestría; Fisiología Vegetal; Floral capitulums; Flavonoids; Sages of flowering develoment; Growth kinetics.
Ano: 2009
URL: http://hdl.handle.net/10521/1562

Actividad de pal, acumulación de fenoles y flavonoides en el chile CM-334 infectado por Nacobbus aberrans e inoculado en el follaje con Phytophthora capsici.
Provedor de dados: 32
Autores: Sandoval Luna, Ruth.
Se evaluó la respuesta del chile (Capsicum annuum) CM-334 infectado con Nacobbus aberrans (Na) y en el follaje inoculado con diferentes tipos de inoculación de Phytophthora capsici. En plantas completas o con el tallo decapitado se inoculo micelio, en el follaje zoosporas asperjadas, por inmersión en una suspensión de zoosporas y también en la raíz. Se tuvieron experimentos con plantas susceptibles (var. Joe E. Parker) y resistentes (CM-334), infectadas o sin infectar con N. aberrans y 21 días posteriores a la inoculación (pi) con el nematodo se inocularon con P. capsici; bajo un diseño completamente al azar en cámaras bioclimáticas. De los 5 a los 30 días pi con el oomiceto (pio) se registró la longitud de necrosis (cm), la colonización de hoja, tallo o...
Palavras-chave: Chile CM-334; Fenoles; Flavonoides; PAL; Micelio; Phytophthora capsici; Follaje; Nacobbus aberrans; Zoosporas; Pepper CM-334; Phenols; Flavonoids; Mycelium; Foliage; Zoospores; Fitopatología; Doctorado.
Ano: 2011
URL: http://hdl.handle.net/10521/612

Cuantificación de flavonoides y carotenoides en variedades de caléndula (Calendula officinalis L.) y descriptores varietales.
Provedor de dados: 32
Autores: Palma Tenango, Mariana.
Caléndula (Calendula officinalis L.) es una planta herbácea anual que destaca por los usos medicinales de sus capítulos (flores). En esta especie se ha demostrado diversidad genética y de composición química entre variedades. En México no se cultivan diferentes variedades ni se ha investigado la variación posible en el rendimiento de capítulos, concentración de flavonoides y carotenoides en función de la variedad y de cortes, como es el efecto causado por cosechas continuas de los capítulos florales. El objetivo de este estudio fue determinar el rendimiento, concentración de flavonoides y carotenoides en seis variedades de caléndula aquí seleccionadas, cuyos capítulos fueron cosechados a lo largo de siete cortes en 2010 y de nueve cortes en 2011, de...
Palavras-chave: Caléndula; Flavonoides; Carotenoides; Descripción varietal; Pot marigold; Flavonoids; Carotenoids; Description varietal; Fisiología vegetal; Doctorado.
Ano: 2014
URL: http://hdl.handle.net/10521/2274

Antigenotoxicity and antimutagenicity of ethanolic extracts of Brazilian green propolis and its main botanical source determined by the Allium cepa test system
Provedor de dados: 74
Autores: Roberto,Matheus Mantuanelli; Jamal,Cláudia Masrouah; Malaspina,Osmar; Marin-Morales,Maria Aparecida.
Abstract Brazilian green propolis is a resinous substance prepared by bees from parts of the plant Baccharis dracunculifolia. As it possess several biological properties, this work assessed the cytotoxic/anticytotoxic, genotoxic/antigenotoxic and mutagenic/antimutagenic potential of ethanolic extracts of Brazilian green propolis (EEGP) and of B. dracunculifolia (EEBD), by means of the Allium cepa test system. The effects were evaluated by assessing the chromosomal aberrations (CA) and micronuclei (MN) frequencies on meristematic and F1 generation cells from onion roots. Chemical analyses performed with the extracts showed differences in flavonoid quality and quantity. No genotoxic or mutagenic potential was detected, and both extracts were capable of...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Chromosomal aberration; Micronucleus; Anticlastogenicity; Protective effects; Flavonoids.
Ano: 2016
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572016000200257

Phytochemical analysis and fungicide potential of Pouteria ramiflora against Lasiodiplodia theobromae
Provedor de dados: 75
Autores: Oliveira,Ademir Kleber M; Rizzi,Elvia Silvia; Pereira,Kelly Cristina L; Bono,José Antônio M; Matias,José Carlos Pina; Rosemary.
ABSTRACT The use of plant extracts can be an alternative to reduce the use of pesticides, to control diseases and pests that affect agricultural production. The aim of this study was the chemical characterization of the extract and fractions of Pouteria ramiflora leaves and to determine its fungistatic potential on Lasiodiplodia theobromae. The ethanolic extract of dried and crushed leaves was obtained by maceration. Part of this extract was sequentially partitioned and the following fractions were obtained: hexane, dichloromethane, chloroform, ethyl acetate, n-butyl, and hydromethanol for subsequent bioassay, and qualitative and quantitative phytochemical analysis. Experimental development comprises of adding a L. theobromae mycelial disk (5 mm), obtained...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Pathogen; Natural products; Organic farming; Flavonoids.
Ano: 2017
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-05362017000400564

Otimização e validação de técnica voltamétrica para a detecção e quantificação de compostos fenólicos de interesse agrícola: ácidos fenólicos, flavonoides, taninos e estilbenos.
Provedor de dados: 14
Autores: MAGARELLI, G.; CAVALCANTE, R. S.; CASTRO, C. S. P. de.
bitstream/item/217643/1/Boletim-fenolicos-366-final1.pdf
Tipo: Boletim de Pesquisa e Desenvolvimento (INFOTECA-E)
Palavras-chave: Voltammetry; Method validation; Reducing power; Oxidation potential; Voltametria; Validação de métodos; Poder redutor; Potencial de oxidação; Phenolic acids; Flavonoids; Tannins; Stilbenes.
Ano: 2020
URL: http://www.infoteca.cnptia.embrapa.br/infoteca/handle/doc/1126457

Antibacterial activity of propolis collected in different regions of Brazil
Provedor de dados: 80
Autores: Gonsales,G. Z.; Orsi,R. O.; Fernandes Júnior,A.; Rodrigues,P.; Funari,S. R. C.
The aim of this study was to investigate the antibacterial activity of propolis samples from Goiás, Paraná and São Paulo States, Brazil, and their flavonoids content. Ethanolic extracts of propolis (EEP) were prepared (30g of propolis in 70% ethanol), and the microorganisms Staphylococcus aureus and Escherichia coli were tested. The methodology employed was agar diffusion using filter paper discs. Ampicillin and tetracycline were used as controls. Antibacterial activity was determined by the reading of inhibition zone diameters (mm) after 24 hours incubation at 37°C. Results demonstrated that EEP inhibited the growth of Staphylococcus aureus but not that of Escherichia coli. Tetracycline and ampicillin showed an efficient action against both bacteria....
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Propolis; Antibacterial activity; Flavonoids.
Ano: 2006
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992006000200009

Water stress before harvest of pepper-rosmarin
Provedor de dados: 86
Autores: Alvarenga,Ivan Caldeira Almeida; Valadares,Rafael Vasconcelos; Martins,Ernane Ronie; Oliveira,Flávio Gonçalves; Figueiredo,Lourdes Silva de; Kobayashi,Mauro Koji.
The objective of this work was to assess the effect of different periods of water stress before harvest of pepper-rosmarin (Lippia sidoides) on the contents of essential oil and flavonoids. The experiment was carried out during 270 days of cultivation, with drainage lysimeters, in a completely randomized block design with five treatments: 0, 2, 4, 6, and 8 days of water suppression before harvest, with four replicates. Fresh and dry matter yield, essential oil content, total flavonoids content, and water potential and temperature of leaves were determined. There was a decrease of approximately 50% in oil content and of 60% in total flavonoid content with the reduction of leaf water potential in 0.3 MPa. Essential oil is more sensitive to water stress than...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Lippia sidoides; Essential oil; Flavonoids; Leaf water potential; Medicinal plant; Water stress.
Ano: 2011
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-204X2011000700005

Physicochemical attributes and functional properties of flowers of Brazilian feijoa genotypes
Provedor de dados: 86
Autores: Amarante,Cassandro Vidal Talamini do; Souza,Alexandra Goede de; Benincá,Thalita Dal Toé; Steffens,Cristiano André; Ciotta,Marlise Nara.
Abstract: The objective of this work was to characterize entire flowers of the feijoa (Acca sellowiana) genotypes 'Alcântara', 'Helena', 'Mattos', 'Nonante', and the accession 2316 for dry matter, total antioxidant activity (TAA), and the contents of soluble solids, ascorbic acid, total anthocyanins, total flavonoids, and total phenolic compounds (TPC), as well as for the petal surface areas and colors. The TAA was quantified by the ABTS and DPPH methods. Flowers of the accession 2316 and of the cultivars Alcântara and Helena showed the highest contents of anthocyanins and flavonoids, as well as the highest values of TPC and TAA. The feijoa genotypes cultivated in Southern Brazil show high contents of soluble solids and represent a natural source of...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Acca sellowiana; Anthocyanins; Ascorbic acid; Flavonoids; Soluble solids; Total antioxidant activity; Total phenolic compounds.
Ano: 2019
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-204X2019000102701

Performance, body composition, and physiological response of tambaqui fed diet with green tea extract
Provedor de dados: 86
Autores: Corrêa,Carline Barroso; Veras,Galileu Crovatto; Silva,Giselle Paula Silva da; Brabo,Marcos Ferreira; Silva,Evaldo Martins.
Abstract: The objective of this work was to evaluate the performance, body composition, and physiological state of tambaqui (Colossoma macropomum) fingerlings fed diets containing different levels of green tea (Camellia sinensis) extract (GTE). A completely randomized design was used with five treatments, different levels of GTE (0.00, 0.05, 0.30, 0.55, and 0.80 g kg-1) and three replicates. The diets were offered to fingerlings twice a day, for 90 days. The increase of dietary GTE levels promoted a positive quadratic effect on body lipids, hepatic lipids, retention of body lipids, glucose, and total triglycerides, and the minimum values of these variables were estimated with 0.61, 0.54, 0.73, 0.60, and 0.30g kg-1 GTE in the diet, respectively. There was a...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Camellia sinensis; Colossoma macropomum; Flavonoids; Lipid reduction; Phytotherapy; Plant extracts.
Ano: 2018
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-204X2018000500540

Teor de flavonóides e fenóis totais em folhas de Pyrostegia venusta Miers. de mata e de cerrado
Provedor de dados: 88
Autores: SANTOS,MÁRCIA DÉBORA DOS; BLATT,CECÍLIA TERUMI TERADAIRA.
Foram realizadas análises quantitativas de flavonóides, fenóis solúveis e taninos de folhas de Pyrostegia venusta coletadas na mata e no cerrado, com o objetivo de verificar a influência desses biócoros na sua produção. Tanto os resultados de flavonóides como os de fenóis não mostraram diferenças significativas entre as plantas de mata e cerrado, sugerindo que a espécie não apresenta plasticidade fenotípica baseada nesses caracteres, considerando as diferenças de solo dos locais de coleta. Não foram detectados taninos nas folhas desta espécie.
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Flavonoids; Total phenolics; Tannins; Pyrostegia venusta.
Ano: 1998
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-84041998000200004

Foliar flavonoids of nine species of Bauhinia
Provedor de dados: 88
Autores: SALATINO,ANTONIO; BLATT,CECÍLIA T.T.; SANTOS,DÉBORAH Y.A.C. DOS; VAZ,ANGELA M.S.F.
Foliar flavonoids of nine species of Bauhinia were isolated and identified. All the compounds correspond to glycosides derived from kaempferol, quercetin, isorhamnetin and myricetin. Derivatives of the latter aglyconhe seem to be rare in Bauhinia. Derivatives of isorhamnetin are commonly found in species of subgenus Bauhinia and were not detected in the two species of subgenus Phanera. Flavonoid patterns of species of the former subgenus are in general more complex than those of the latter.
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Bauhinia; Caesalpinioideae; Flavonoids; Chemotaxonomy.
Ano: 1999
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-84041999000100003

Ascorbic acid and citric flavonoids for broilers under heat stress: effects on performance and meat quality
Provedor de dados: 89
Autores: Peña,JEM; Vieira,SL; López,J; Reis,RN; Barros,R; Furtado,FVF; Silva,PX.
The aim of this study was to evaluate the effects of increasing doses of ascorbic acid (AA) and citric flavonoids (quercetin and rutin) on the performance and meat quality characteristics of broilers submitted to cyclic heat stress. Four-hundred one-day-old female Ross 308 were housed in 40 battery cages a in temperature controlled room. Treatments consisted of 0, 250, 500, and 1000 g/ton on of AA + citric flavonoids. Birds were fed ad libitum until 32 day of age. Beginning on day 14 post-hatch until the end of the experiment, in order to simulate cyclic heat stress, the temperature inside the room was increased to 32°C for 5 hours, and decreased until reaching the comfort temperature corresponding to the age of the animals. Birds were slaughtered at 33...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Ascorbic acid; Broiler; Heat stress; Flavonoids.
Ano: 2008
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2008000200008

Inhibitory Effects of Some Flavonoids on Thioredoxin Reductase Purified from Chicken Liver
Provedor de dados: 89
Autores: Türkoğlu,E.A; Kuzu,M; Ayasan,T; Inci,H; Eratak,SV.
ABSTRACT Thioredoxin reductases (TrxRs) are selenocysteine-containing flavoenzymes that reduce Trxin NADPH-dependent manner. In the view of the direct vital role of TrxR in a wide range of biochemical and physiological processes, methods to inhibit this enzyme are clinically important. TrxR has recently emerged as a new candidate in anticancer drug investigations because of overexpression in tumorous cells. In this study, TrxR from chick liver was purified 94.6-fold with a yield of 4.86% and a specific activity of 0.19 EU/mg. KM and Vmax values of TrxR for DTNB were calculated as 0.9 mM and 0,03 EU/mL, respectively. Then, the effects of the flavonoids hesperidin, naringenin, chlorogenic acid, ferulic acid, naringin, 3,4-dihydoxybenzoic acid, and ellagic...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Flavonoids; Inhibitors; Natural products; Thioredoxin reductase.
Ano: 2019
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2019000200345

Flavonoids and mannanoligosaccharides in broiler diets
Provedor de dados: 89
Autores: Batista,LS; Garcia,EA; Faitarone,ABG; Sherer,MR; Móri,C; Pelícia,K; Pizzolante,CC.
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Antibiotic; Broilers; Flavonoids; Mannan oligosaccharides; Probiotic.
Ano: 2007
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2007000100005

Fruit quality attributes of low chilling requirement ‘Snowchaser’ blueberry cultivated in Brazil
Provedor de dados: 94
Autores: Jimenes,Isabela Maria; Silva,Simone Rodrigues da; Tezotto-Uliana,Jaqueline Visioni; Cantuarias-Avilés,Tatiana.
Abstract  In Brazil there are still few studies on the post-harvest quality of low-chill blueberry cultivars, which have been recently introduced in the country. ‘Snowchaser’ blueberries were evaluated during a six-day storage period regarding fruit physical and chemical properties, and its antioxidant capacity. During fruit storage there was an increased weight loss and maintenance of some skin color properties such as luminosity (L*) and b*, whereas the values of parameter a* decreased and chroma (C) values increased. The levels of anthocyanins and flavonoids in the pulp increased, as well as the antioxidant activity. Maximum fruit shelf life at room temperature was six days without reduction on the antioxidant activity along the period, which is...
Tipo: Info:eu-repo/semantics/other
Palavras-chave: Vaccinium corymbosum; Weight loss; Color; Anthocyanins; Flavonoids; Antioxidant activity.
Ano: 2018
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-29452018000105001

PHENOLIC COMPOSITION AND ANTIOXIDANT CAPACITY OF AQUEOUS AND ETHANOLIC EXTRACTS OF BLACKBERRIES
Provedor de dados: 94
Autores: CELANT,VIVIANE MARCELA; BRAGA,GILBERTO COSTA; VORPAGEL,JESSICA ARIANE; SALIBE,ARIANE BUSCH.
ABSTRACT  The objective of this work was to evaluate the content of phenolic compounds, anthocyanins and flavonoids extracted with 80% ethanol and water, and antioxidant capacity (DPPH and ABTS) of five blackberry cultivars produced in Western Paraná, Brazil. Brazos, Tupy, Arapaho, Choctaw and Guarani blackberries were studied. Soluble solids, titratable acidity and ascorbic acid of fruits were also characterized. Total phenolic compounds ranged from 8.23 to 14.98 mg GAE g-1 (f.w.) and Arapaho cultivar exhibited the highest contents in both solvents. Anthocyanins ranged from 2.57 to 9.42 mg ECy3glu g-1 (f.w.), being the solvent ethanol 80% more efficient than the water, and Choctaw cultivar showing the highest content. Flavonoids ranged from 0.46 to 1.14...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Rubus spp.; Total phenolic; Flavonoids; Anthocyanins.
Ano: 2016
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-29452016000200202

Physical-chemical and chemical characterization of Passiflora cincinnata Mast fruits conducted in vertical shoot positioned trellis and horizontal trellises system
Provedor de dados: 94
Autores: D’abadia,Ana Claudia Alves; Costa,Ana Maria; Faleiro,Fábio Gelape; Malaquias,Juaci Vitória; Araújo,Francisco Pinheiro de.
Abstract Passiflora cincinnata Mast. or Caatinga passion fruit is widely cultivated in the northeastern semi-arid regions of Goiás, Minas Gerais, and Bahia. The system of cultivation and field management of the Passiflora species affects the physicochemical quality of its fruits. In this study, we evaluated the chemical and physico-chemical characteristics of the fruits of 2 progenies (CPEF2220 and CBAF2334) of P. cincinnata species using the vertical and horizontal trellis system. Fruits were collected from the plants at their physiological maturation stage and tested for the fruit skin color and texture and the pH, total soluble solids, titratable acidity, pulp acidity ratio, and the contents of flavonoids, anthocyanins, and polyphenols in the seedless...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Flavonoids; Coloration; Polyphenols; Acidity.
Ano: 2019
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-29452019000600901

Green propolis extract as additive in the diet for lambs in feedlot
Provedor de dados: 96
Autores: Ítavo,Camila Celeste Brandão Ferreira; Graça Morais,Maria da; Ramos,Cristhian Liber; Ítavo,Luís Carlos Vinhas; Tomich,Thierry Ribeiro; Silva,Jonilson Araújo da.
The objective of this paper is to assess the effects of the inclusion of different levels of green propolis extract in the diet of lambs in feedlot on ingestive behavior, nutrients digestibility, physiological parameters and performance. Eight lambs were distributed in double Latin Square with four treatments, corresponding to the inclusion levels (4, 8, 12, 16 mL) of green propolis ethanolic extract (30 g of ground crude propolis was infused in a 100-mL hydroalcoholic solution, 700 mL/L). The diets were composed of Brachiaria brizantha cv. MG5 hay and a commercial concentrate (roughage:concentrate ratio was 50:50) in a dry matter basis. No effect was observed on dry matter (31.2 g/kg of BW), crude protein, ether extract, neutral detergent fiber,...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Additive; Apis mellifera; Flavonoids; Ionophore.
Ano: 2011
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982011000900021

Effects of dietary brown propolis on nutrient intake and digestibility in feedlot lambs
Provedor de dados: 96
Autores: Silva,Jonilson Araújo da; Ítavo,Camila Celeste Brandão Ferreira; Ítavo,Luís Carlos Vinhas; Morais,Maria da Graça; Franco,Gumercindo Loriano; Zeoula,Lucia Maria; Heimbach,Natália da Silva.
The present study tested brown propolis in crude or extract form as a feed supplement for feedlot lambs to identify the type that most improves in vivo nutrient digestibility. Digestibility was assessed by both total fecal collection and internal markers and the results obtained by these techniques were compared. The completely randomized design was used to compare feed intake and nutrient digestibility of 24 male lambs aged seven months among four dietary treatments (crude brown propolis, propolis ethanol extract, monensin sodium, and control). Methods of feces collection were compared using a completely randomized split-plot design, with experimental diets corresponding to the main factor and the methods to estimate fecal production as the sub-factor....
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Flavonoids; Monensin; Ruminants.
Ano: 2014
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982014000700376

Effects of phenolic compounds in propolis on digestive and ruminal parameters in dairy cows
Provedor de dados: 96
Autores: Aguiar,Sílvia Cristina de; Paula,Eduardo Marostegan de; Yoshimura,Emerson Henri; Santos,Wallacy Barbacena Rosa dos; Machado,Erica; Valero,Maribel Velandia; Santos,Geraldo Tadeu dos; Zeoula,Lucia Maria.
Four rumen-cannulated primiparous lactating cows were studied in a 4 × 4 Latin square design experiment to evaluate the effects of propolis-based products (PBP) with different concentrations of propolis and alcohol levels on total digestibility, (TD), ruminal digestibility (RD), intestinal digestibility (ID), pH, ruminal ammonia-nitrogen production (NH3-N), rumen microbial synthesis, and blood parameters. The feed consisted of 591.9 g/kg corn silage and 408.1 g/kg concentrate (dry matter [DM] basis), and treatments differed with regard to the inclusion (via ruminal cannula) or exclusion of PBP as follows: control (without the PBP), PBP B1 (3.81 mg of phenolic compounds/kg of ingested DM), PBP C1 (3.27 mg of phenolic compounds/kg of ingested DM), and PBP C3...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Additive; Ammonia nitrogen; Flavonoids; Phenolic acids; Ruminants.
Ano: 2014
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982014000400197

Standardization of the quality control parameters of the Tamarindus indica L. soft extract
Provedor de dados: 98
Autores: Rodríguez-Amado,Jesús; Pérez Rosés,Renato; Escalona-Arranz,Julio César; Lafourcade Prada,Ariadna; Sierra González,Gustavo.
Introduction: Tamarindus indica L or Tamarind as commonly known is a medicinal plant witha broad spectrum of application in medicine. Tamarind is the most useful plant for liver disorders treatment in Cuba and The Caribbean. People use it as decoction and have to take up to four liters a day of this preparation, because the use of alcohol in the Tamarind fluid extracts prevent its use in patient with lever desorders. Objective: the aim of this study was the preliminary establisment of quality control parameters of the Tamarindus indica L. soft extract as a novel alcohol-free active ingredient for solids pharmaceutical formulation. Methods: organoleptics properties, total solids, relative density, pH, and total ashes were stablished. The polyphenols content...
Tipo: Journal article
Palavras-chave: Soft extract; Polyphenols; Flavonoids; Antioxidant; Tamarind; Tamarindus indica.
Ano: 2012
URL: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1028-47962012000100012

Structure-biological activity relationship of synthetic trihydroxilated chalcones
Provedor de dados: 59
Autores: Devia,Cristina M.; Pappano,Nora B.; Debattista,Nora B.
The bacteriostatic activity of 2’,4’,2-trihydroxychalcone; 2’,4’,3-trihydroxychalcone and 2’,4’,4-trihydroxychalcone, prepared by condensation of 2,4-dihydroxyacetophenone and benzaldehyde substituted, against Staphylococcus aureus ATCC 25923 was assayed by agar plate method. The three compounds presented important inhibition halos. In order to elucidate structure-activity relationships, the minimal inhibitory concentrations against S. aureus were determined by the broth dilution method and the results obtained were compared to that of 2',4'-dihydroxychalcone. The sequence observed was: MIC 2’,4’,3-(OH)3 &amp;gt; MIC 2’,4’-(OH)2 &amp;gt; MIC 2’,4’,4-(OH)3 &amp;gt; &amp;gt; MIC 2’,4’,2-(OH)3. These results showed that the introduction of an electron...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Bacteriostatic activity; Structure-activity relationship; Flavonoids; Trihydroxylated chalcones.
Ano: 1998
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37141998000400014

DEVELOPMENT OF ARBUSCULAR MYCORRHIZAL FUNGI IN THE PRESENCE OF DIFFERENT PATTERNS OF Trifolium repens SHOOT FLAVONOIDS
Provedor de dados: 127
Autores: Scervino,José Martín; Ponce,María Alejandra; Delia Monica,Ivana; Vierheilig,Horst; Ocampo,Juan Antonio; Godeas,Alicia.
We tested the effects of the flavonoid 3-methoxi-5,6,7,8-hydroxy-4'hydroxy flavone (NMHTV) isolated from shoots of non arbuscular mycorrhizal (AM) inoculated clover, and of the flavonoids 5,6,7,8-hydroxy-3-methoxy flavone (MH-1); 5,6,7,8-hydroxy-4'-hydroxy flavone (MH-2); and 5,7-hydroxy-3,4'-methoxy flavone (MH-3); isolated from AM clover {Trifolium repens) shoots, on spore germination, hyphal length, hyphal branches and the number of cluster of auxiliary cells or the number of secondary spores (Presymbiotic stage) and on the number of entry points and the percentage of AM colonized root of tomato (Lycopersicum esculentum) by the AM fungi Gigaspora rosea, Giaspora margarita, Glomus mosseae and Glomus intraradices (Symbiotic stage). Non significant effects...
Tipo: Journal article
Palavras-chave: Arbuscular mycorrhizas; Flavonoids; Signal molecules; Symbiosis.
Ano: 2009
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-27912009000200002

Histochemical aspects of wheat resistance to leaf blast mediated by silicon
Provedor de dados: 63
Autores: Silva,Washington Luís da; Cruz,Maria Fernanda Antunes; Fortunato,Alessandro Antônio; Rodrigues,Fabrício Ávila.
Blast, caused by Pyricularia oryzae, has become a significant disease threat to wheat (Triticum aestivum L.) in Brazil. This study aimed to investigate at the histochemical level if silicon (Si) could enhance the production of flavonoids in the leaves of wheat plants in response to P. oryzae infection. Plants from the Aliança cultivar, which are susceptible to blast, were grown in hydroponic cultures containing 0 (-Si) or 2 mM of Si (+Si) and inoculated by spraying a conidial suspension of P. oryzae (1 × 105 conidia mL−1) on all adaxial leaf surfaces of plants at 60 days after emergence (growth stage 65). The fourth and fifth leaves of each plant were used to evaluate blast severity at 24, 36, 48, 72 and 96 h after inoculation (hai). At 96 hai, leaves were...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Pyricularia oryzae; Flavonoids; Histochemistry; Phenolics.
Ano: 2015
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-90162015000400322

Trellis systems, rootstocks and season influence on the phenolic composition of ‘Chenin Blanc’ grape
Provedor de dados: 63
Autores: Costa,Rayssa Ribeiro da; Rodrigues,Antônio Augusto Marques; Vasconcelos,Victor Alexandre Freire de; Costa,João Paulo Dias; Lima,Maria Auxiliadora Coêlho de.
ABSTRACT: The biosynthesis of phenolic compounds might be influenced by environmental factors, such as solar radiation, temperature and relative air humidity, and production system. Some components of the production system, particularly the trellis system and rootstock, might change the phenolic composition of grapes due to microclimate of the cultivation region. In this study, the phenolic profile of ‘Chenin Blanc’ grapes was characterized with different trellis systems and rootstocks in two consecutive production cycles by using high-performance liquid chromatography under tropical semi-arid conditions. In the second production cycle (Jan-May/2016), accumulation of (-) - epicatechin gallate and (-) - epigallocatechin gallate was higher when vigorous...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Vitis vinifera L.; Phenolic acids; Flavonoids; Stilbenes; Tropical vitiviniculture.
Ano: 2020
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-90162020000301300

Oleanonic acid from Lippia lupulina (Verbenaceae) shows strong in vitro antileishmanial and antitrypanosomal activity
Provedor de dados: 36
Autores: FUNARI,Cristiano S.; ALMEIDA,Letícia de; PASSALACQUA,Thais G.; MARTINEZ,Isabel; AMBRÓSIO,Daniela L.; CICARELLI,Regina Maria B.; SILVA,Dulce Helena S.; GRAMINHA,Márcia A. S.
ABSTRACT Leishmaniasis and Chagas disease affect millions of people in tropical and subtropical regions. Drugs used currently to treat such diseases often present undesirable side effects and low efficiency. The aim of this work was to identify extracts and isolated compounds from the genus Lippia with leishmanicidal and trypanocidal activity. Fifteen extracts from different plant parts of Lippia species with partially known chemical compositions, four partition fractions, six compounds and a mixture of four interconverting flavanones previously isolated from Lippia salviaefolia and Lippia lupulina were assayed in vitro towards epimastigote forms of Trypanosoma cruzi and promastigote forms of Leishmania amazonensis. The root extract of L. lupulina had...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Leishmanicidal; Trypanocidal; Triterpenoids; Flavonoids; T. cruzi.
Ano: 2016
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672016000400411

Seasonal effects and antifungal activity from bark chemical constituents of Sterculia apetala (Malvaceae) at Pantanal of Miranda, Mato Grosso do Sul, Brazil
Provedor de dados: 36
Autores: FONTOURA,Fernanda Mussi; MATIAS,Rosemary; LUDWIG,Juliane; OLIVEIRA,Ademir Kleber Morbeck de; BONO,José Antonio Maior; MARTINS,Pedro de Figueiredo Rocha Barbosa; CORSINO,Joaquim; GUEDES,Neiva Maria Robaldo.
In the Southern Pantanal, the hyacinth macaw (Anodorhynchus hyacinthinus), an endangered species, often chooses the manduvi tree (Sterculia apetala) as a nesting site, because of its physical properties. In addition, the chemical composition of the wood may also contribute to a nesting selection by the hyacinth macaws. The objective of this study was to determine the main chemical components of S. apetala bark for two seasons, and evaluate its fungicidal potential. Bark samples from S. apetala trees with and without nests of A. hyacinthinus were collected in January (wet season) and August (dry season) of 2012. The inhibition of mycelium growth (MGI) from tree samples with and without nests were assessed using a phytochemical analysis to evaluate their...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Manduvi; Anodorhynchus hyacinthinus; Trichoderma sp.; Secondary metabolites; Flavonoids.
Ano: 2015
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672015000300283

Flavonoid profiling and nodulation of some legumes in response to the allelopathic stress of Sonchus oleraceus L.
Provedor de dados: 39
Autores: Gomaa,Nasr Hassan; Hassan,Mahmoud Omar; Fahmy,Gamal Mohammad; González,Luís; Hammouda,Ola; Atteya,Atteya Mostafa.
Annual sowthistle (Sonchus oleraceus) has been reported to produce allelopathic effects. Two greenhouse experiments were conducted to estimate the allelopathic potential of both plant residue and root exudates of S. oleraceus on flavonoid composition and nodulation in a leguminous crop, Trifolium alexandrinum, and in two leguminous weeds, Melilotus indicus and T. resupinatum. The results of high performance liquid chromatography-mass spectrometry (HPLC-MS/MS) showed that all three legumes contained six flavonoid aglycones: apigenin, daidzein, kaempferol, luteolin, myricetin and quercetin; and seven flavonoid glycosides: daidzin, genistin, hesperidin, hyperoside, kaempferol-7-O-glucoside, naringin and rutin. In general, both plant residue and root exudates...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Allelopathy; Flavonoids; Legumes; Nodulation; Sonchus oleraceus.
Ano: 2015
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-33062015000400553

UV-B radiation as an elicitor of secondary metabolite production in plants of the genus Alternanthera
Provedor de dados: 39
Autores: Klein,Fátima Rosane S.; Reis,Andressa; Kleinowski,Alítcia M.; Telles,Renata T.; Amarante,Luciano do; Peters,José A.; Braga,Eugenia Jacira B.
ABSTRACT Ultraviolet B radiation has been described as a potential elicitor agent of the synthesis of secondary metabolites in plants. Thus, the present study aimed to investigate the production of betalains and total flavonoids, as well as the antioxidant activity, of Alternanthera sessilis, A. brasiliana, A. tenella and A. philoxeroides exposed to different periods of UV-B radiation (280-315 nm). Plants of these four species were exposed to UV-B radiation for 0, 2, 4, 6, and 8 hours, which amounts to 0, 10, 20, 30, and 40 J cm−2 of radiation, respectively. Significant increases in betacyanin and betaxanthin levels were observed in A. sessilis and A. brasiliana during the period of UV-B exposure, while no differences were observed for the others species....
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Abiotic elicitor; Antioxidants; Flavonoids; Medicinal plants; Pigments; Ultraviolet radiation.
Ano: 2018
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-33062018000400615

Seasonal variation in allelopathic potential of the leaves of Copaifera langsdorffii Desf.
Provedor de dados: 39
Autores: Franco,Danilo Miralha; Saldanha,Luiz Leonardo; Neto,José de Sousa Lima; Santos,Lourdes Campaner dos; Dokkedal,Anne Ligia; Almeida,Luiz Fernando Rolim de.
ABSTRACT The deciduous plant Copaifera langsdorffii contains important medicinal compounds which may also be allelopathic and inhibitory to plant growth. The species is endemic to the Brazilian Cerrado where there is pronounced climatic seasonality. In this study we demonstrate the allelopathic capacity of extracts from the leaves of C. langsdorffii and pre-purified fractions of the extract. Analysis by HPLC-PAD-ESI-MS confirmed the presence of quercetin-3-O-α-rhamnoside and kaempferol-3-O-α-rhamnoside as major components, as well as phenolic acid derivatives of gallic acid. The extracts from samples collected during the wet season were rich in flavonoids and reduced the seed germination rate, root emergence time, and root growth of Sorghum bicolor...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Fabaceae; Flavonoids; HPLC-PAD-ESI-MS; Kaempferol-3-O-α-rhamnoside; Quercetin-3-O-α-rhamnoside; Root growth.
Ano: 2016
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-33062016000200157

Phenolic content and antioxidant activity of parts of Passiflora edulis as a function of plant developmental stage
Provedor de dados: 39
Autores: Guimarães,Sarah F.; Lima,Inorbert M.; Modolo,Luzia V.
ABSTRACT Passiflora edulis Sims var. flavicarpa O. Deg. (Yellow-passion fruit) is the native plant species most used by juice industries in Brazil while its leaf extracts are widely employed in folk medicine. This study evaluated the phenolic content of leaves, roots, fruit shells and pulp of plants of P. edulis in juvenile, flowering and fruiting stages. The extent of scavenging and/or degradation of reactive nitrogen and oxygen species by plant extracts was also investigated. Leaves were the organs that most accumulated phenolics/flavonoids, regardless of plant developmental stage. Leaf extracts efficiently scavenged DPPH by up to 67 % while root and fruit shell extracts effectively captured up to 80 % O2 -. Maximum activity of catalase (51.6 mmol H2O2...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Antioxidant enzymes; DPPH; Flavonoids; Passion fruit; Secondary metabolism; Superoxide anion.
Ano: 2020
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-33062020000100074

Performance, digestibility, microbial production and carcass characteristics of feedlot young bulls fed diets containing propolis - doi: 10.4025/actascianimsci.v34i4.15167
Provedor de dados: 2
Autores: Aguiar, Sílvia Cristina de; Universidade Estadual de Maringá; Zeoula, Lúcia Maria; Universidade Estadual de Maringá; Moura, Lucimar Pontara Peres de; Universidade Estadual de Maringá; Prado, Ivanor Nunes do; Universidade Estadual de Maringá; Paula, Eduardo Marostegan de; Universidade Estadual de Maringá; Samensari, Rafael Barreiros; Universidade Estadual de Maringá.
The objective was to evaluate the effect of propolis-based products (PBP) on performance, digestibility, microbial production and carcass characteristics of feedlot young bulls. Twenty-seven crossbred young bulls were used, with 353 ± 28 kg of body weight in a completely randomized experimental design, divided in three treatments: two diets with PBP with different dosages (PBP1=  0.018 mg g-1 and PBP2= 0.036 mg g-1 of total flavonoids in chrysin) and control diet (CON). To determine total digestibility, the indigestible dry matter was used as an internal marker, while microbial production was estimated from purine derivatives in urine, collected by the spot method. The evaluated carcass characteristics were: hot carcass weight, dressing percentage,...
Palavras-chave: 5.04.00.00-2 additive; Flavonoids; Meat quality; Microbial efficiency; Ruminant additive; Flavonoids; Meat quality; Microbial efficiency; Ruminant.
Ano: 2012
URL: http://periodicos.uem.br/ojs/index.php/ActaSciAnimSci/article/view/15167

Production of pigments in Alternanthera sessilis calli mediated by plant growth regulators and light
Provedor de dados: 3
Autores: Milech, Cristini; Lucho, Simone Ribeiro; Kleinowski, Alítcia Moraes; Dutra, Débora Barwaldt; Soares, Mariana Mühlenberg; Braga, Eugenia Jacira Bolacel.
Among the compounds produced by plants, pigments such as betalains have received attention from both food and pharmaceuticals industries. The Alternanthera sessilis species produces these pigments, though in small quantities, and so it is necessary to increase production. Thus, many studies use elicitors that are capable of triggering physiological or morphological responses in plants. The objective was to establish callus production in A. sessilis grown under different combinations of growth regulators and light qualities and to assess whether these factors can increase betalain and flavonoid production. Leaf and internodal explants in MS medium with different growth regulators were used to obtain calli, which were subsequently transferred to a betacyanin...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Betalain; Flavonoids; Secondary metabolites; Medicinal plants.
Ano: 2017
URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/36312

Protective role of Syzygium cumini leaf extracts against paraquat-induced oxidative stress in superoxide-dismutase-deficient Saccharomyces cerevisiae strains
Provedor de dados: 3
Autores: Soares, Jefferson de Jesus; Rosa, Anderson da Silva; Motta, Paola Ribeiro; Cibin, Francielli Weber Santos; Roehrs, Rafael; Denardin, Elton Luís Gasparotto.
The aim of this study was to evaluate the protective effect of three different extracts prepared from Syzygium cumini leaves against paraquat-induced toxicity in Saccharomyces cerevisiae strains deficient in superoxide dismutase (SOD). Additionally, the extracts phenolic and flavonoid contents, in vitro antioxidant activity, and phytochemical composition (using high-pressure liquid chromatography) were determined. Bioactive compounds from S. cumini leaves were extracted with infusion (traditional method) or ultrasound (aqueous or hydroalcoholic). Compared to the infusion extract, the ultrasound extracts exhibited a greater protective capacity against paraquat toxicity in the yeast cells as well as higher antioxidant activity. These results may be directly...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Traditional medicine; Antioxidant activity; Phenolic compounds; Flavonoids; Syzygium cumini; Saccharomyces cerevisiae.
Ano: 2019
URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/47139

Improving drought tolerance of quinoa plant by foliar treatment of trehalose
Provedor de dados: 111
Autores: Dawood, Mona Gergis.
Two field experiments were conducted during two successive seasons (2014/2015 and 2015/2016) at the Experimental Station of National Research Centre, Nubaria district, Beheira Governorate, Egypt, to study the effect of foliar treatment of quinoa plants with trehalose (Tre) (100µM and 500µM) on growth, photosynthetic pigments, seed yield quantity &amp; quality, in fever of nutritional and antioxidant compounds in the yielded quinoa seeds which subjected to water deficiency (skipping two irrigation times at 50 &amp; 60 days after sowing). Water deficiency caused marked decreases in quinoa plant growth parameters (shoot height, fresh and dry weights of shoot/plant) and photosynthetic pigments with marked increases in root growth parameters (root length, fresh...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Antioxidant activity; Drought; Flavonoids; Oil; Phenolics; Protein; Quinoa; Trehalose.
Ano: 2018
URL: http://www.cigrjournal.org/index.php/Ejounral/article/view/4539

Total phenolic compounds, flavonoids and antioxidant activity in the flowers of Crataegus spp. from México
Provedor de dados: 115
Autores: García-Mateos,Rosario; Aguilar-Santelises,Leonor; Soto-Hernández,Marcos; Nieto-Angel,Raúl; Kite,Geoffrey.
There are a number of medicinally active phytochemicals isolated from hawthorn with most of the data generated in studies of those species that are native to Europe and Asia. Comparatively little is known about the North American, specifically the Mexican Crataegus species. The objective of this study was to evaluate phenolic compounds, flavonoids and antioxidant activity of extracts of flowers from six Mexican accessions of Crataegus in order to contribute to the chemistry of the Germplasm Bank accessions at the Universidad Autonóma Chapingo. Antioxidant activity was evaluated using DPPH (2,2-diphenyl-1-picrylhydrazyl) method and the flavonoids were identified by HPLC-MS. Quercetin- 3-O-glucoside, quercetin-3-O-rhamnoside, quercetin...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Crataegus; Flavonoids; Flowers; Mexican hawthorn; Radical scavenging activity.
Ano: 2012
URL: http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S1405-31952012000700002

Chemical composition, botanical evaluation and screening of radical scavenging activity of collected pollen by the stingless bees Melipona rufiventris (Uruçu-amarela)
Provedor de dados: 42
Autores: Silva,Tania M.S.; Camara,Celso A.; Lins,Antonio C.S.; Agra,Maria de Fátima; Silva,Eva M.S.; Reis,Igor T.; Freitas,Breno M.
Stingless bees in Brazil are indigenous and found all over the country. Bee pollen is used for its nutritional value in the human diet. It is made up of natural flower pollen mixed with nectar and bee secretions. In order to evaluate the chemical composition, free radical scavenging activity, and botanical origin, sample of pollen loads from stingless bee, Melipona rufiventris (Uruçu amarela) was studied. The EtOAc extract of pollen of Melipona rufiventris yielded the following compounds: p-hydroxycinnamic acid, dihydroquercetin, isorhamnetin, isorhamnetin3-O-(6"-O-E-p-coumaroyl)-β-D-glucopyranoside, luteolin, and quercetin. This is the first report of the isolation of isorhamnetin3-O-(6"O-E-p-coumaroyl)β-D-glucopyranoside from pollen. The free...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Antioxidant activity; Bee pollen; Flavonoids; Melipona rufiventris; Uruçu amarela.
Ano: 2009
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652009000200003

Flavonoids from leaves of Derris urucu: assessment of potential effects on seed germination and development of weeds
Provedor de dados: 42
Autores: SILVA,EWERTON A.S. DA; LÔBO,LÍVIA T.; SILVA,GEILSON A. DA; SOUZA FILHO,ANTONIO PEDRO DA S.; SILVA,MILTON N. DA; ARRUDA,ALBERTO C.; GUILHON,GISELLE M.S.P.; SANTOS,LOURIVALDO S.; ARRUDA,MARA S.P.
In some previous studies, we described the isolation of nine compounds from leaves of Derris urucu, a species found widely in the Amazon rainforest, identified as five stilbenes and four dihydroflavonols. In this work, three of these dihydroflavonols [urucuol A (1), urucuol B (2) and isotirumalin (3)] were evaluated to identify their potential as allelochemicals, and we are also reporting the isolation and structural determination of a new flavonoid [5,3′-dihydroxy-4′-methoxy-(7,6:5″,6″)-2″,2″-dimethylpyranoflavanone (4)]. We investigated the effects of the dihydroflavonols 1-3 on seed germination and radicle and hypocotyl growth of the weed Mimosa pudica, using solutions at 150 mg.L–1. Urucuol B, alone, was the substance with the greatest potential to...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Derris urucu; Flavonoids; Allelopathy; Development of weeds; Seed germination.
Ano: 2013
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652013000300881

A comparative study of phytoconstituents and antibacterial activity of in vitro derived materials of four Passiflora species
Provedor de dados: 42
Autores: J. SIMÃO,MARIELA; J.S. BARBOZA,THIAGO; G. VIANNA,MARCELA; GARCIA,RENATA; MANSUR,ELISABETH; P.R. IGNACIO,ANA CLAUDIA; PACHECO,GEORGIA.
Abstract Passiflora species are well known for their common use in popular medicine for the treatment of several diseases, such as insomnia, anxiety, and hysteria, in addition to their anti-inflammatory, antioxidant, analgesic and antibacterial potential. However, few data about the chemical composition and the medicinal potential of in vitro derived materials are available. Therefore, the goal of this work was to compare, for the first time, the phytoconstituents of in vitro derived materials of four Passiflora species, and evaluate the antibacterial potential of their extracts against 20 Gram-positive and negative strains. Chromatographic analysis indicated the presence of saponins in roots extracts from all studied species, whereas leaf extracts...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Antibacterial; Chromatography; Flavonoids; Passiflora; Saponins.
Ano: 2018
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000602805

Phytochemical profile and antimicrobial properties of Lotus spp. (Fabaceae)
Provedor de dados: 42
Autores: GIRARDI,FELIPE A.; TONIAL,FABIANA; CHINI,SILVIA O.; SOBOTTKA,ANDRÉA M.; SCHEFFER-BASSO,SIMONE M.; BERTOL,CHARISE D.
The phytochemical profile and antimicrobial activity of cultivar (cv.) extracts of Lotus uliginosus (cvs. Trojan and Serrano), L. tenuis (cv. Larrañaga) and L. corniculatus (cv. São Gabriel) were investigated. The phytochemical analysis revealed tannins, coumarins and flavonoids in all extracts, with variations among cultivars, showing genotypic variability. By High Performance Liquid Chromatographic method, the cvs. Larrañaga and São Gabriel showed the highest percentage of catechin and epicatechin, respectively, and presented rutin, which was not detected in the other ones. These genotypes showed antifungal activity but not antibacterial one. The cv. Larrañaga inhibited the mycelia growth of Alternaria sp. and Fusarium graminearum while the cv. São...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Alternaria; Flavonoids; Fusarium; Tannins.
Ano: 2014
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652014000301295

Antioxidant activity and flavonoid content of Clusia fluminensis Planch. &amp;amp; Triana
Provedor de dados: 42
Autores: Silva,Maria Carolina A. da; Paiva,Selma R.
Clusia fluminensis Planch. &amp;amp; Triana (Clusiaceae Lindl.) is a native species found in regions of high luminosity and water restriction. The aim of this study was to evaluate the antioxidant activity of Clusia fluminensis crude extracts through the scavenging of the stable free radical DPPH, and the determination of flavones and flavonols content in these extracts. The fruit acetonic extract showed the lowest EC50 value (2.71 ± 0.34 g extract / g DPPH), the lowest percentage of remaining DPPH at the concentrations of 125 and 250 µg/mL (about 4% in both), and also the greatest percentage of flavones and flavonols (13.93 ± 0.21 %). Statistical analysis suggests a positive correlation between the presence of flavonoids and the antioxidant activity of...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Aluminum chloride; Clusia fluminensis; DPPH; Flavonoids.
Ano: 2012
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652012000300004

Flavonoids of Lonchocarpus montanus A.M.G. Azevedo and biological activity
Provedor de dados: 42
Autores: Magalhães,Aderbal F.; Tozzi,Ana Maria G.A.; Magalhães,Eva G.; Sannomiya,Miriam; Soriano,Maria del Pilar C.; Perez,Mary A.F.
The analysis of root extracts from Lonchocarpus montanus A.M.G. Azevedo resulted in the isolation of twenty three compounds chiefly flavonoids of which five (four flavonoids and one benzophenone) are described for the first time. The molecular structures of the new compounds (1-5) were determined through spectral analysis (UV, IR, MS and NMR) as being: 2'-hydroxy-8-(&lt;FONT FACE=Symbol&gt;a,a&lt;/FONT&gt;-dimethylallyl)-2", 2"-dimethylpyrano-(5",6":3',4')-dibenzoylmethane (1), 2'-methoxy-8-(&lt;FONT FACE=Symbol&gt;a, a&lt;/FONT&gt;-dimethylallyl)-2", 2"-dimethylpyrano-(5",6":3',4')-dibenzoylmethane (2), 4'-methoxy-2",2"-dimethylpyrano-(5",6":8,7)-flavone (3), 2"-(1-hydroxy-1-methylethyl)-furano-(4",5":8,7)-flavone (4) and...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Lonchocarpus montanus A.M.G. Azevedo; Leguminosae; Dibenzoylmethanes; Flavonoids; Flavones; Benzophenone; Bioautography; Artemia salina lethality.
Ano: 2007
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652007000300001

Antiproliferative activity in tumor cell lines, antioxidant capacity and total phenolic, flavonoid and tannin contents of  Myrciaria floribunda
Provedor de dados: 42
Autores: TIETBOHL,LUIS A.C.; OLIVEIRA,ADRIANA P.; ESTEVES,RICARDO S.; ALBUQUERQUE,RICARDO D.D.G.; FOLLY,DIOGO; MACHADO,FRANCISCO P.; CORRÊA,ARTHUR L.; SANTOS,MARCELO G.; RUIZ,ANA L.G.; ROCHA,LEANDRO.
ABSTRACT Myrciaria floribunda (H. West ex Willd.) O. Berg, Myrtaceae, is a native plant species of the Atlantic Rain Forest, from north to south of Brazil. The lyophilized ethyl acetate extract from the leaves of M. floribunda was investigated for its antiproliferative activity in tumor cell lines, antioxidant capacity and its total phenolic, flavonoid and tannin contents. Antiproliferative activity was tested in vitro against seven human cancer cells and against immortalized human skin keratinocytes line (HaCat, no cancer cell). Antioxidant activity was determined using 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging and oxygen radical absorbing capacity (ORAC) assays and total phenolic, flavonoid and tannin contents were determined by...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Antiproliferative; Flavonoids; Myrciaria floribunda; Phenols.
Ano: 2017
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000301111

Clusia criuva Cambess. (Clusiaceae): anatomical characterization, chemical prospecting and antioxidant activity
Provedor de dados: 42
Autores: SILVA,KARLA M.M. DA; NÓBREGA,ANDREA B. DA; LESSA,BRUNO; ANHOLETI,MARIA CAROLINA; LOBÃO,ADRIANA Q.; VALVERDE,ALESSANDRA L.; PAIVA,SELMA R. DE; JOFFILY,ANA.
ABSTRACT This study aims the anatomical description and chemical characterization of aerial parts of Clusia criuva Cambess., Clusiaceae in addition to the evaluation of the antioxidant activity of crude extracts, correlated to the flavonoid content. The morphological characterization was performed using traditional techniques of plant anatomy. For phytochemical studies, crude extracts were obtained by static maceration and analyzed by thin layer chromatography. The antioxidant activity and the flavonoids content were determined by colorimetric methods involving, respectively, 2,2-diphenyl-1-picrylhydrazyl free radical and aluminum chloride. C. criuva has uniseriate epidermis, paracytic stomata, hypostomatic leaves, cuticular flanges and cordiform vascular...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Morphoanatomy; Antioxidant activity; Chemical prospecting; Clusia criuva; Clusiaceae; Flavonoids.
Ano: 2017
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000401565

Gastroprotective effect of Byrsonima sericea DC leaf extract against ethanol-induced gastric injury and its possible mechanisms of action
Provedor de dados: 42
Autores: Rodrigues,Patrícia A.; Morais,Selene M.; Souza,Carolina M.; Magalhães,Davi V.; Vieira,Ícaro G.P.; Andrade,Geanne M.; Rao,Vietla S.; Santos,Flávia A.
Byrsonima sericea leaves are extensively used in folk medicine in Brazil against gastric disorders. This study investigated the chemical constituents of B. sericea leaf ethanolic extract (BSLE) and its potential gastroprotective activity, with its possible mechanism of the action using ethanol to induce gastric mucosal damage in mice. The phytochemical analysis was carried out to identify the active constituents present in the extract, and the HPLC analysis was performed for the identification of flavonoids. BSLE at oral doses of 125, 250 and 500 mg/kg markedly attenuated the ethanol-evoked gastric lesions by 53.2, 84.9 and 87.6 %, respectively. The BSLE (250 mg/kg) prevented the depletion of gastric mucus and gastric mucosal nonproteic-sulfhydryl groups,...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Antioxidant; Byrsonima sericea; Flavonoids; Gastroprotection; Mechanisms of action.
Ano: 2012
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652012000100011

Effects of diet supplementation with Camu-camu (Myrciaria dubia HBK McVaugh) fruit in a rat model of diet-induced obesity
Provedor de dados: 42
Autores: Nascimento,Ozanildo V; Boleti,Ana P.A; Yuyama,Lucia K.O; Lima,Emerson S.
Amazonian Camu-camu fruit (Myrciaria dubia HBK Mc Vaugh) has attracted interest from food and cosmetics industries because of its rich content of vitamin C, flavonoids and anthocyanins. The goal of this study was investigates the antiobesity action of the ingestion of the Camu-camu pulp in a rat model of diet-induced obesity. Wistar rats with obesity induced by subcutaneous injection of monosodium glutamate receiving diet ad libitum. The rats were divided in two groups: an experimental group that ingested 25 mL/day of Camu-camu pulp (CCG) and a non treated group (CG). After 12 weeks, the animals were sacrificed. Blood, liver, heart, white adipose tissues were collected and weighted, biochemical and inflammatory profiles were determinate as well. Animals...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Amazonian fruit; Flavonoids; Lipid profile; Myrciaria dubia; Obesity.
Ano: 2013
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652013000100355

Chemical constituents of Piptadenia gonoacantha (Mart.) J.F. Macbr (pau jacaré)
Provedor de dados: 42
Autores: Carvalho,Mário G. de; Cardozo,Maritza A.R.; Catunda Junior,Francisco E.A.; Carvalho,Acácio G. de.
The phytochemical investigation of Piptadenia gonoacantha (Mart.) J.F. Macbr. (Leguminosae-Mimosoideae), commonly known as "pau jacaré" (alligator stick), afforded sitosterol, campesterol, stigmasterol, the N-benzoylphenylalanine-2-benzoylamide-3-phenylpropyl ester, known as asperphenamate, sitosterol-3-O-β-D-glucopyranoside, besides three flavonoids, apigenin, 5-O-methylapigenin and 7,4'-dihydroxy-3',5-dimethoxyflavone from its branches. From its leaves, the methyl gallate and two flavonoids, vitexin and isovitexin, were isolated. From its bark, a mixture of sitosterol, campesterol, and stigmasterol, besides a mixture of cycloartenone, cycloartan-25-en-3-one, and 24-methylene-cycloartenone, and the pure triterpenes 24-methylenecycloartanol, friedelin,...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Leguminoseae; Piptadenia gonoacantha; Terpenoids; Asperphenamate; Flavonoids; "pau jacaré"; Piptadenia gonoacantha.
Ano: 2010
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652010000300003

Changes in the phenylalanine ammonia lyase activity, total phenolic compounds, and flavonoids in Prosopis glandulosa treated with cadmium and copper
Provedor de dados: 42
Autores: GONZÁLEZ-MENDOZA,DANIEL; TRONCOSO-ROJAS,ROSALBA; GONZALEZ-SOTO,TANIA; GRIMALDO-JUAREZ,ONECIMO; CECEÑA-DURAN,CARLOS; DURAN-HERNANDEZ,DAGOBERTO; GUTIERREZ-MICELI,FEDERICO.
ABSTRACT The aim of the present work is to evaluate the changes on the phenylalanine ammonia lyase (PAL) activity, phenolic compounds accumulation and photochemical efficiency in leaves of P. glandulosa treated with Cd2+ (0.001 M) and Cu2+ (0.52 M) concentrations for 96 h under hydroponic conditions. The results showed that only leaves treated with copper had a decrease in photochemical efficiency and leaf epidermal polyphenols in P. glandulosa leaves after 96 h of exposure. On the other hand the reverse-phase HPLC analysis revealed higher levels of phenolic compound (gallic, vanillic and caffeic acids) and flavonoids (rutin and kaempferol-3-O-glucosides) in plant leaves from Cu and Cd-treatments with respect to control plants. Finally, highest increments...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Heavy metals; Prosopis glandulosa; Flavonoids; Chlorophyll a fluorescence.
Ano: 2018
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000401465

Special metabolites isolated from Urochloa humidicola (Poaceae)
Provedor de dados: 42
Autores: OLIVEIRA,DÉBORA R. DE; NEPOMUCENO,DELCI D.; CASTRO,ROSANE N.; BRAZ FILHO,RAIMUNDO; CARVALHO,MÁRIO G. DE.
ABSTRACT This study aims to identify special metabolites in polar extracts from Urochloa humidicola (synonym Brachiaria humidicola) that have allelopathic effects and induce secondary photosensitization in ruminants. The compounds were isolated and identified via chromatographic and spectroscopic techniques. The compounds 4-hydroxy-3-methoxy-benzoic acid, trans-4-hydroxycinnamic acid, and p-hydroxy-benzoic acid; the flavonols isorhamnetin-3-O-β-d-glucopyranoside and methyl quercetin-3-O-β-d-glucuronate; and kaempferitrin, quercetin-3-O-α-l-rhamnopyranoside, and tricin were identified in the extract from the leaves of Urochloa humidicola. Two furostanic saponins, namely, dioscin and...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Brachiaria humidicola; Flavonoids; Steroidal saponins; Urochloa.
Ano: 2017
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000300789

Chemical and agronomic development of Kalanchoe brasiliensis Camb. and Kalanchoe pinnata (Lamk.) Pers under light and temperature levels
Provedor de dados: 42
Autores: Cruz,Bruna P.; Chedier,Luciana M.; Fabri,Rodrigo L.; Pimenta,Daniel S.
This study compares the development of Kalanchoe brasiliensis and Kalanchoe pinnata, which are medicinal species known as "saião" and "folha da fortuna" that are used interchangeably by the population for medicinal purposes. The experiment consisted of 20 plots/species planted in plastic bags with homogeneous substrate in a randomized design, which grown under light levels (25%, 50%, 70%, full sunlight) at environment temperature, and a treatment under a plastic with greater temperature range than the external environment. It was obtained for K. pinnata a greater plant height, total length of sprouts, stems, production and dry matter content of leaves than that obtained for K. brasiliensis, which achieved higher averages only for the length of lateral...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Kalanchoe; Luminosity; Mucilage; Flavonoids.
Ano: 2011
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652011000400030

Chemical constituents from Vellozia graminifolia (Velloziaceae)
Provedor de dados: 42
Autores: Branco,Alexsandro; Pinto,Angelo C.; Braz Filho,Raimundo.
From the hexane and ethyl acetate extracts obtained from stems, roots and leaf sheaths of Vellozia graminifolia, a mixture of linear hydrocarbons, a mixture of pentacyclic triterpenes, five monoisoprenylated flavonoids and one labdane diterpene, (-)-ent-3beta-hydroxy-8(17)-labden-15-oic acid, were isolated. The linear hydrocarbons and minor triterpenes were identified in their corresponding mixtures by High Resolution Gas Chromatography (HRGC) and HRGC coupled to mass spectrometry. The major pentacyclic triterpenes and the diterpene were characterized by spectral data, including 2D NMR experiments, and chemical transformations.
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Vellozia graminifolia; Velloziaceae; Triterpenes; Diterpene; Flavonoids.
Ano: 2004
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652004000300005

Genotoxic Maillard byproducts in current phytopharmaceutical preparations of Echinodorus grandiflorus
Provedor de dados: 42
Autores: LIMA-DELLAMORA,ELISANGELA C.; WALDHELM,KASSIA C.V.; ALVES,ADRIANA M.; LAGE,CLAUDIA A.S.; LEITÃO,ALVARO A.C.; KUSTER,RICARDO M.
Extracts of Echinodorus grandiflorus obtained from dried leaves by three different techniques were evaluated by bacterial lysogenic induction assay (Inductest) in relation to their genotoxic properties. Before being added to test cultures, extracts were sterilized either by steam sterilization or ultraviolet light. Only the extracts prepared by infusion and steam sterilized have shown genotoxic activity. The phytochemical analysis revealed the presence of the flavonoids isovitexin, isoorientin, swertisin and swertiajaponin, isolated from a genotoxic fraction. They were assayed separately and tested negative in the Inductest protocol. The development of browning color and sweet smell in extracts submitted to heat, prompted further chemical analysis in...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Echinodorus grandiflorus; Genotoxicity; Maillard's Reaction; Flavonoids.
Ano: 2014
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652014000301385

Bioactivities of the ethanol extract from Ageratum fastigiatum branches: antioxidant, antinociceptive and anti-inflammatory
Provedor de dados: 42
Autores: DEL-VECHIO-VIEIRA,GLAUCIEMAR; SANTOS,BRUNA C.S.; ALVES,MARIA SILVANA; ARAÚJO,AÍLSON L.A.; YAMAMOTO,CÉLIA H.; PINTO,MÍRIAM A.O.; KAPLAN,MARIA AUXILIADORA C.; SOUSA,ORLANDO V.
ABSTRACT The present study was designed to investigate the antioxidant, antinociceptive and anti-inflammatory activities of the ethanol extract from Ageratum fastigiatum branches. Phytochemical screening and total phenol and flavonoid contents were determined. The antioxidant activity was assessed by 2,2-diphenyl-1-pycrilhydrazin (DPPH) and iron reducing power methods. The antinociceptive effect was evaluated using the acetic acid-induced writhing, formalin, hot plate and tail immersion assays; while the carrageenan-induced paw edema and pleurisy tests were performed to examine the anti-inflammatory activity against acute inflammation. The extract revealed the presence of flavonoids, tannins, coumarins, terpenes, sterols and saponins. Expressive levels of...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Ageratum fastigiatum; Analgesic; Anti-inflammatory; Antioxidant; Flavonoids; Total phenols.
Ano: 2016
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000401471

Mineral composition, nutritional properties, total phenolics and flavonoids compounds of the atemoya fruit (Annona squamosa L. x Annona cherimola Mill.) and evaluation using multivariate analysis techniques
Provedor de dados: 42
Autores: SANTOS,WALTER N.L. DOS; SAUTHIER,MARIA CELESTE S.; CAVALCANTE,DANNUZA D.; BENEVIDES,CLÍCIA M.J.; DIAS,FÁBIO S.; SANTOS,DANIELE C.M.B.
ABSTRACT The atemoya is a hybrid fruit obtained by crossing of cherimoya (Annona cherimola Mill.) with sweet sop (Annona squamosa L.). The information about chemical composition of atemoya is scarce. The mineral composition was evaluated employing Inductively Coupled Plasma Optical Emission Spectrometry (ICP OES) and the centesimal composition and the physico-chemical parameters were assessed employing procedures described in the AOAC methods. The total phenolic compounds (TPC) and total flavonoids (TF) were determined using spectroanalytical methods. Considering the Reference Daily Intake (RDI), the concentrations of K, Cu and Vitamin C found in atemoya were the highest, representing about 32, 23 and 37% of the RDI, respectively. The total carbohydrates...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Atemoya; Food composition; ICP OES; Flavonoids; Phenolics.
Ano: 2016
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000401243

Flavonoids from Lonchocarpus muehlbergianus
Provedor de dados: 42
Autores: Magalhães,Aderbal F.; Tozzi,Ana M.G.A.; Magalhães,Eva G.; Blanco,Ivani S.; Soriano,Maria-Del-Pilar C.
The light petroleum extract from the roots of Lonchocarpus muehlbergianus Hassl contained nine flavonoids, including six new ones. These are 2,4-cis-2,4,5,8-tetramethoxy-(2´´,3´´:6,7)-furanoflavan; 2,4-cis-4-hydroxy-2,5,8-trimethoxy-(2´´,3´´:6,7)-furanoflavan; 2,4-cis-2-prenyloxy-4,5,8-trimethoxy-(2´´,3´´:6,7)-fu-ranoflavan; 2,4-cis-2-prenyloxy-4-hydroxy-5,8-dimethoxy-(2´´,3´´:6,7)-furanoflavan; 2',5',6'-trimethoxy-9-(1,1-dimethylallyoxy)-[2´´,3´´:3´,4´]-furanochalcone; 5,6-dimethoxy-(2´´,3´´:7,8)-furanoflavone, identi-fied by analysis of their spectral data (UV, IR, ¹H and 13C NMR, 2D-NMR, NOE and MS). The natural occurrence of 2,4-dioxygenated flavan derivatives is being reported for the first time. Quantitative analysis of the petrol extract, by using...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Lonchocarpus muehlbergianus; Leguminosae; Flavonoids; Flavans.
Ano: 2004
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652004000400004

(+)-Catechin and (-)-epigallocatechin gallate: are these promising antioxidant therapies for frozen goat semen?
Provedor de dados: 45
Autores: Silva,E.C.B.; Arruda,L.C.P.; Vieira,J.I.T.; Soares,P.C.; Guerra,M.M.P.
ABSTRACT The aim of this study was to evaluate the effects of different concentrations of (+)-catechin or (-)-epigallocatechin gallate (EGCG) on goat semen freezability. Poolsof semen were processed (Experiment 1: 0, 15, 25, 50, 75, or 100µM (+)-catechin; Experiment 2: 0, 15, 25, 50, 75, or 100µM EGCG) and frozen. After thawing, the samples were evaluated for kinematics, plasma membrane (PMi) and acrosome integrity, morphology, and oxidative stress, at 0 and 1h. In Experiment 1, at 0h, VSL and VAP were greater (P&lt;0.05) with 15µM than with 50 and 100; WOB was lower (P&lt;0.05) with 100µM than with 0, 15, and 25; and BCF was higher (P&lt;0.05) with 75 and 100µM than with 0. In turn, in Experiment 2, progressive motility was higher (P&lt;0.05) with0 and...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Antioxidants; Cryopreservation; Flavonoids; Oxidative stress; Semen.
Ano: 2019
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000200521

Synergism of flavonoids with bacteriostatic action gainst Staphylococcus aureus ATCC 25 923 and Escherichia coli ATCC 25 922
Provedor de dados: 47
Autores: Alvarez,María De Los A.; Debattista,Nora B.; Pappano,Nora B.
In our previous studies, bacteriostatic action of flavonoids against Staphylococcus aureus ATCC 25 923 and Escherichia coli ATCC 25 922 was demostrated. In the present work synergism of their combinations in order to improve the bacteriostatic action against the same microorganisms was determined. The experiences were made in nutritive broth, maintaining constant one drug concentration (20 µg/ml) and increasing the other one. A turbidimetric kinetic method was used and by means of a mechanism previously proposed, the minimal inhibitory concentrations (MIC´s) of each flavonoid combination were determined. The MIC´s for assayed combinations against S. aureus were: variable morin - constant rutin: 157.44 µg/ml and variable quercetin - constant morin: 29.9...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Synergism; Flavonoids; Bacteriostatics; MIC.
Ano: 2006
URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452006000100006

Investigations of anticholinestrase and antioxidant potentials of methanolic extract, subsequent fractions, crude saponins and flavonoids isolated from Isodon rugosus
Provedor de dados: 48
Autores: Zeb,Anwar; Sadiq,Abdul; Ullah,Farhat; Ahmad,Sajjad; Ayaz,Muhammad.
BACKGROUND: Based on the ethnomedicinal uses and the effective outcomes of natural products in various diseases, this study was designed to evaluate Isodon rugosus as possible remedy in oxidative stress, alzheimer's and other neurodegenerative diseases. Acetylecholinestrase (AChE) and butyrylcholinesterase (BChE) inhibitory activities of crude methanolic extract (Ir.Cr), resultant fractions (n-hexane (Ir.Hex), chloroform (Ir.Cf), ethyl acetate (Ir.EtAc), aqueous (Ir.Aq)), flavonoids (Ir.Flv) and crude saponins (Ir.Sp) of I. rugosus were investigated using Ellman's spectrophotometric method. Antioxidant potential of I. rugosus was determined using DPPH, H2O2 and ABTS free radicals scavenging assays. Total phenolic and flavonoids contents of plant extracts...
Tipo: Journal article
Palavras-chave: Anticholinesterase; Antioxidant; Flavonoids; Phenolics; Saponins; Isodon rugosus.
Ano: 2014
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100070

The application of multiplex fluorimetric sensor for the analysis of flavonoids content in the medicinal herbs family Asteraceae, Lamiaceae, Rosaceae
Provedor de dados: 48
Autores: Sytar,Oksana; Bruckova,Klaudia; Hunkova,Elena; Zivcak,Marek; Konate,Kiessoun; Brestic,Marian.
BACKGROUND: The aim of our research work was to quantify total flavonoid contents in the leaves of 13 plant species family Asteraceae, 8 representatives of family Lamiaceae and 9 plant species belonging to familyRosaceae, using the multiplex fluorimetric sensor. Fluorescence was measured using optical fluorescence apparatus Multiplex(R) 3 (Force-A, France) for non-destructive flavonoids estimation. The content of total flavonoids was estimated by FLAV index (expressed in relative units), that is deduced from flavonoids UV absorbing properties. RESULTS: Among observed plant species, the highest amount of total flavonoids has been found in leaves ofHelianthus multiflorus (1.65 RU) and Echinops ritro (1.27 RU), Rudbeckia fulgida (1.13 RU) belonging to the...
Tipo: Journal article
Palavras-chave: Non-destructive measurement; Flavonoids; Multiplex fluorimetric sensor; Asteraceae; Lamiaceae; Rosaceae.
Ano: 2015
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100005

Defense mechanisms of Solanum tuberosum L. in response to attack by plant-pathogenic bacteria
Provedor de dados: 48
Autores: POIATTI,VERA A D; DALMAS,FERNANDO R; ASTARITA,LEANDRO V.
The natural resistance of plants to disease is based not only on preformed mechanisms, but also on induced mechanisms. The defense mechanisms present in resistant plants may also be found in susceptible ones. This study attempted to analyze the metabolic alterations in plants of the potato Solanum tuberosum L. cv. Agata that were inoculated with the incompatible plant-pathogenic bacteria X. axonopodis and R. solanacearum, and the compatible bacterium E. carotovora. Levels of total phenolic compounds, including the flavonoid group, and the activities of polyphenol oxidase (PPO) and peroxidase (POX) were evaluated. Bacteria compatibility was evaluated by means of infiltration of tubers. The defense response was evaluated in the leaves of the potato plants....
Tipo: Journal article
Palavras-chave: Flavonoids; Hypersensitive response; Peroxidases; Phenolic compounds.
Ano: 2009
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602009000200009

Evaluation of Anticancer Activity of Extracted Flavonoids from Morus Alba Leaves and its interaction with DNA
Provedor de dados: 52
Autores: Fallah,Soudabeh; Hajihassan,Zahra; Zarkar,Nasrin; Chadegani,Azra Rabbani-; Mohammadnejad,Javad; Hajimirzamohammad,Milad.
ABSTRACT Morous Alba, known as white mulberry contains many oxidative flavonoids, widely used in the treatment of many diseases like hyperglycemia, inflammation, fever and cancer. In the present study we investigated the interaction of extracted flavonoids from Iranian Morus Alba leaves with DNA as a main target for anticancer drugs. Various spectroscopic techniques (UV/Vis, CD and Fluorescence Spectroscopy) were used to detect the interaction. In vivo studies also were done to confirm the effectiveness of the extracted flavonoids. The spectroscopic results showed that the extracted flavonoids bind to DNA especially to the sugar-phosphate backbone and making DNA conformational changes upon this binding. Experiments on the cancerous mice with solid tumors...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Flavonoids; Anticancer activity; DNA interaction; Morus Alba.
Ano: 2018
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132018000100002

Effect of Salicylic Acid, 2,4-D and 2i-P on the Production of Secondary Metabolites in Garcinia brasiliensis Mart. Callus
Provedor de dados: 52
Autores: Teixeira,Maria Gessi; Carvalho,Marília; Leite,Marco Aurélio; Barbosa,Sandro; Santos filho,Plinio Rodrigues dos; Santos,Breno Régis.
Abstract The aim of this work was to evaluate the effect of Salicylic acid, 2,4-D and 2-iP on the production of total phenolic and flavonoids as well in the levels of fukugetin and 7-epiclusianone in callus of Garcinia brasiliensis zygotic embryos. For this, Bacupari callus were exposed to different concentrations (0.0; 0.1; 1; 10; 100 µM) of Salicylic acid (SA) in the presence or in the absence of 72 μM 2-iP and 28.73 μM 2,4-D. The highest concentration of total phenolic occurred in the treatment with 100 μM SA in callus subcultured in the absence of 2,4-D and 2-iP, and with 10 μM SA in callus subcultured in the presence of these regulators. Concerning flavonoids, 2,4-D and 2-iP supplementation without the presence of the SA was sufficient for the highest...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Bacupari; Phenols; Flavonoids; 7-epiclusianone; Fukugetin.
Ano: 2019
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132019000100407

High-yield production of scutellaria radix flavonoids (baicalein, baicalin and wogonin) by liquid-culture of Scutellaria baicalensis root-derived cells
Provedor de dados: 52
Autores: Ohtsuki,Takashi; Himeji,Mika; Fukazawa,Harumi; Tanaka,Miho; Yamamoto,Hisako; Mimura,Akio.
Production of baicalein, baicalin and wogonin by liquid culture of Scutellaria baicalensis cells derived from the plant root was studied. The maximum production obtained were 119 mg/L of baicalein at two week, 1372 mg/L of baicalin at eight week, and 14 mg/L of wogonin at two week. In addition, the production of baicalin was drastically increased to 1000 mg/L level at 3-week culture, and the extremely high production rate (339 mg/L•week) was obtained. In the comparison of total antioxidative activities among baicalein, baicalin and wogonin, evaluated by thiocyanate method, it was suggested that the location of hydroxyl groups both at 5- and 6-position contributed to enhancement of radical scavenging activity, and/or methoxylation at 8-position diminished...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Antioxidant; Flavonoids; Liquid culture; High-yield production; Scutellaria baicalensis.
Ano: 2009
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000200005

An evaluation of antibacterial activities of Psidium guajava (L.)
Provedor de dados: 52
Autores: Sanches,Neviton Rogério; Garcia Cortez,Diógenes Aparício; Schiavini,Michelle Simone; Nakamura,Celso Vataru; Dias Filho,Benedito Prado.
The present study was designated to evaluate the antibacterial activities of aqueous and ethanol:water extracts from leaves, roots and stem bark of Psidium guajava L. The antibacterial activities of the extracts against bacteria were tested by using both microdilution assay. The aqueous extracts of P. guajava leaves, roots and stem bark were active against the gram-positive bacteria Staphylococcus aureus (MICs=500, 125 and 250 µg/ml, respectively) and Bacillus subtilis (MICs=500 µg/ml), and virtually inactive against the gram-negative bacteria Escherichia coli and Pseudomonas aeruginosa (MICs &gt;1000 µg/ml). The ethanol:water extracts showed higher antimicrobial activity as compared to aqueous extracts. Based on this finding, the ethanol:water extract of...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Psidium guajava; Antibacterial activities; Flavonoids; Alpha- and beta-amyrin; Beta-sitosterol.
Ano: 2005
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000300014

Eugenia Klotzschiana O. Berg Fruits as New Sources of Nutrients: Determination of their Bioactive Compounds, Antioxidant Activity and Chemical Composition
Provedor de dados: 52
Autores: Carneiro,Nárgella Silva; Alves,Cássia Cristina Fernandes; Cagnin,Caroline; Belisario,Celso Martins; Silva,Marco Antônio Pereira da; Miranda,Mayker Lazaro Dantas; Oliveira Filho,Josemar Gonçalves de; Alves,José Milton; Pereira,Paulo Sérgio; Silva,Fabiano Guimarães; Egea,Mariana Buranelo.
Abstract: The Cerrado is one of the world's biodiversity hotspots and Brazil’s second largest biome. Many native species of the Brazilian Cerrado provide fruits that have unique sensory characteristics and high nutritional value. This study aimed at characterizing the pulp of Eugenia klotzschiana O. Berg, concerning its proximal composition, bioactive compound content and antioxidant activity. The pulp under study had high moisture (89.47 g kg-1) and caloric (96.07 kcal kg-1) values whereas its contents of protein (0.59 g kg-1) and lipids (2.35 g kg-1) were low. The cerrado pear pulp also had high iron content (16.5 mg kg -1) and dietary fiber (6.45 g kg-1), besides 0.034-0,055 mg kg-1 carotenoids, 8.66 mg kg-1 ascorbic acid and 0.66 mg kg-1 total...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Cerrado pear; Nutrients; Flavonoids; Antioxidant capacity.
Ano: 2019
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132019000100402

Production, Composition, Fatty Acids Profile and Stability of Milk and Blood Composition of Dairy Cows Fed High Polyunsaturated Fatty Acids Diets and Sticky Coffee Hull
Provedor de dados: 52
Autores: Santos,Geraldo Tadeu dos; Schogor,Ana Luiza Bachmann; Romero,Jakeline Vieira; Lima,Luciano Soares de; Matumoto-Pintro,Paula Toshimi; Grande,Paula Adriana; Kazama,Daniele Cristina da Silva; Santos,Fabio Seiji dos.
Four lactating Holstein cows were assigned to a 4 × 4 Latin square design to determine the effects of feeding sticky coffee hull (SCH) as a source of antioxidants on dairy cows fed with high PUFA diets. The treatments (on DM basis) were control diet, diet with 30 g/kg of soybean oil, diet with 30 g/kg of soybean oil and 100 g/kg of SCH, and diet with 30 g/kg of soybean oil and 150 g/kg of SCH. Inclusion of 150 g/kg of SCH decreased the crude protein digestibility. Lower values of NDF digestibility were also observed when cows were fed with 100 g/kg and 150g/kg of SCH. The digestibility of NDT was lower in the control and 150 g/kg of SCH diets. Milk production and composition did not differ among the treatments. Inclusion of SCH increased the total...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: By-product; Coffea arabica; Digestibility; Flavonoids; Milk stability; Polyphenols.
Ano: 2014
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132014000400493

Neuroprotection by flavonoids
Provedor de dados: 56
Autores: Dajas,F.; Rivera-Megret,F.; Blasina,F.; Arredondo,F.; Abin-Carriquiry,J.A.; Costa,G.; Echeverry,C.; Lafon,L.; Heizen,H.; Ferreira,M.; Morquio,A.
The high morbidity, high socioeconomic costs and lack of specific treatments are key factors that define the relevance of brain pathology for human health and the importance of research on neuronal protective agents. Epidemiological studies have shown beneficial effects of flavonoids on arteriosclerosis-related pathology in general and neurodegeneration in particular. Flavonoids can protect the brain by their ability to modulate intracellular signals promoting cellular survival. Quercetin and structurally related flavonoids (myricetin, fisetin, luteolin) showed a marked cytoprotective capacity in in vitro experimental conditions in models of predominantly apoptotic death such as that induced by medium concentrations (200 µM) of H2O2 added to PC12 cells in...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Flavonoids; Quercetin; Focal ischemia; Neuroprotection.
Ano: 2003
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003001200002

The action of red wine and purple grape juice on vascular reactivity is independent of plasma lipids in hypercholesterolemic patients
Provedor de dados: 56
Autores: Coimbra,S.R.; Lage,S.H.; Brandizzi,L.; Yoshida,V.; da Luz,P.L.
Although red wine (RW) reduces cardiovascular risk, the mechanisms underlying the effect have not been identified. Correction of endothelial dysfunction by RW flavonoids could be one mechanism. We measured brachial artery reactivity by high-resolution ultrasonography, plasma lipids, glucose, adhesion molecules (ICAM-1 and VCAM), and platelet function in 16 hypercholesterolemic individuals (8 men and 8 women; mean age 51.6 ± 8.1 years) without other risk factors. Twenty-four normal subjects were used as controls for vascular reactivity. Subjects randomly received RW, 250 ml/day, or purple grape juice (GJ), 500 ml/day, for 14 days with an equal wash-out period. At baseline, all 16 subjects were hypercholesterolemic (mean LDL = 181.0 ± 28.7 mg/dl) but HDL,...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Atherosclerosis; Endothelial function; Flavonoids; Alcohol; Red wine and grape juice; Brachial artery dilation.
Ano: 2005
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000900008

Wine, alcohol and atherosclerosis: clinical evidences and mechanisms
Provedor de dados: 56
Autores: Luz,P.L. da; Coimbra,S.R.
Atherosclerosis is a chronic inflammatory disease which may cause obstructions of the coronary, cerebral and peripheral arteries. It is typically multifactorial, most often dependent on risk factors such as hypercholesterolemia, diabetes, smoking, hypertension, sedentarism, and obesity. It is the single main cause of death in most developed countries due to myocardial infarction, angina, sudden death, and heart failure. Several epidemiological studies suggest that moderate alcohol intake, especially red wine, decrease cardiac mortality due to atherosclerosis. The alcohol effect is described by a J curve, suggesting that moderate drinkers may benefit while abstainers and heavy drinkers are at higher risk. Experimental studies indicate that most beneficial...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Coronary disease; Beverages; Drinks and cardiac protection; Flavonoids; Wine and grape juice.
Ano: 2004
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000900001

P-glycoprotein-mediated resistance to chemotherapy in cancer cells: using recombinant cytosolic domains to establish structure-function relationships
Provedor de dados: 56
Autores: Di Pietro,A.; Dayan,G.; Conseil,G.; Steinfels,E.; Krell,T.; Trompier,D.; Baubichon-Cortay,H.; Jault,J.-M.
Resistance to chemotherapy in cancer cells is mainly mediated by overexpression of P-glycoprotein (Pgp), a plasma membrane ATP-binding cassette (ABC) transporter which extrudes cytotoxic drugs at the expense of ATP hydrolysis. Pgp consists of two homologous halves each containing a transmembrane domain and a cytosolic nucleotide-binding domain (NBD) which contains two consensus Walker motifs, A and B, involved in ATP binding and hydrolysis. The protein also contains an S signature characteristic of ABC transporters. The molecular mechanism of Pgp-mediated drug transport is not known. Since the transporter has an extraordinarily broad substrate specificity, its cellular function has been described as a "hydrophobic vacuum cleaner". The limited knowledge...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: P-glycoprotein (Pgp); Multidrug resistance; Anticancer chemotherapy; ATP; Steroids; Flavonoids.
Ano: 1999
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000800001

Binding effect of proline-rich-proteins (PRPs) on in vitro antimicrobial activity of the flavonoids
Provedor de dados: 58
Autores: Ansari,Jawaad Ahmed; Naz,Shahina; Tarar,Omer Mukhtar; Siddiqi,Rahmanullah; Haider,Muhammad Samee; Jamil,Khalid.
The interaction of the cyanidin, pelargonidin, catechin, myrecetin and kaempferol with casein and gelatin, as proline rich proteins (PRPs), was studied. The binding constants calculated for both flavonoid-casein and flavonoid-gelatin were fairly large (105–107 M−1) indicating strong interaction. Due to higher proline content in gelatin, the binding constants of flavonoid-gelatin (2.5 × 105–6.2 × 107M−1) were found to be higher than flavonoid-casein (1.2 × 105–5.0 × 107 M−1). All the flavonoids showed significant antibacterial activity against the tested strains. Significant loss in activity was observed due to the complexation with PRPs confirming that binding effectively reduced the concentration of the free flavonoids to be available for antibacterial...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Proline rich proteins; Flavonoids; Catechin; Myrecetin; Kaempferol; Pelargonidin; Cyanidin; Gelatin; Casein; Binding constants.
Ano: 2015
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000100183

Evaluation of the antimicrobial activity of crude extracts and isolated constituents from Chresta scapigera
Provedor de dados: 58
Autores: Schinor,Elisandra C.; Salvador,Marcos J.; Ito,Izabel Y.; Dias,Diones A.
Crude extracts and eight isolated compounds from Chresta scapigera were evaluated for antibacterial and antifungal activities by the agar-well diffusion method. Twenty strains, including Gram-positive and Gram-negative bacteria and yeasts were used in the bioassay. Hexane extracts presented the best results while ethanol extracts did not indicate inhibition of the microbial growth. Amongst the evaluated compounds b-amyrin acetate, tiliroside and luteolin showed the strongest antimicrobial effect.
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Chresta scapigera; Flavonoids; Triterpenes; Antimicrobial activity.
Ano: 2007
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822007000100030

Inhibitory activity of compounds isolated from Polymnia sonchifolia on aflatoxin production by Aspergillus flavus
Provedor de dados: 58
Autores: Pak,Adriana; Gonçalez,Edlayne; Felicio,Joana D'arc; Pinto,Marina Mori; Rossi,Maria Helena; Simoni,Isabela Cristina; Lopes,Márcia Nasser.
Polymnia sonchifolia, commonly known as ";yacon";, was originally cultivated at Andes moutains in South America. Recently, the specie attracted worldwide attention because of its wide range of uses, for example in the control of diabetes melitus, besides the antifungal and pesticidal compounds were found in the leaves. This study describes the identification of two flavonoids: 3', 5, 7 trihydroxy-3, 4'-dimethoxyflavone (compound 1) and 3', 4', 5- trihydroxy-7-methoxy flavanone (compound 2) and two sesquiterpenes lactones: enhydrin (compound 3) and a mixture of enhydrin and uvedalin (compound 4) isolated from Polymnia sonchifolia leaves and their effects on the aflatoxin production by Aspergillus flavus. The identification of the compounds were achieved by...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Polymnia sonchifolia; Flavonoids; Melampolides; Aflatoxin; Aspergillus flavus.
Ano: 2006
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822006000200018

Quercetin: a flavonoid with the potential to treat asthma
Provedor de dados: 60
Autores: Fortunato,Laila Rigolin; Alves,Claudiney de Freitas; Teixeira,Maxelle Martins; Rogerio,Alexandre Paula.
Allergic asthma is a complex inflammatory disorder characterized by airway hyperresponsiveness, eosinophilic inflammation and hypersecretion of mucus. Current therapies include β2-agonists, cysteinyl leukotriene receptor 1 antagonists and corticosteroids. Although these drugs demonstrate beneficial effects, their adverse side effects limit their long-term use. Thus, the development of new compounds with similar therapeutic activities and reduced side effects is both desirable and necessary. Natural compounds are used in some current therapies, as plant-derived metabolites can relieve disease symptoms in the same manner as allopathic medicines. Quercetin is a flavonoid that is naturally found in many fruits and vegetables and has been shown to exert...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Quercetin; Flavonoids; Asthma.
Ano: 2012
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502012000400002

Memory retrieval improvement by Heteropterys aphrodisiaca in aging rats
Provedor de dados: 60
Autores: Galvão,Suzana Maria Pereira; Mendes,Fúlvio Rieli; Oliveira,Maria Gabriela Menezes de; Mattei,Rita; Mello,João Carlos Palazzo de; Roman Júnior,Walter Antonio; Carlini,Elisaldo de Araújo.
Few data exists about the pharmacological properties of Heteropterys aphrodisiaca O. Mach. (Malpighiaceae), which is native to the scrubland regions of Brazil. The present study investigated the effects of oral treatment with H. aphrodisiaca extract (BST0298) on the learning and memory of young (3-6 months) and aged (21-23 months) rats, and compared the in vitro antioxidant activity of three lots collected in different years. An improvement in the number of sessions to learn the task was observed in the left/right discrimination test in aged rats treated for 45 days with 25 mg/kg (7.0 ± 0.5; p=0.005) or 50 mg/kg (7.6 ± 0.6; p=0.012) compared with control old rats (11.0 ± 1.6). On the other hand, pre-treatment did not improve the performance of...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Heteropterys aphrodisiaca O. Mach/pharmacognosy; Heteropterys aphrodisiaca O. Mach/antioxidant activity; Malpighiaceae/pharmacognosy; Antioxidants; Flavonoids; Plant extract.
Ano: 2011
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000400020

Synthesis and antibacterial activity of a series novel 5,7-diisoprenyloxyflavone derivatives
Provedor de dados: 60
Autores: Jin,Qing-Hao; Fu,Zhi-Yang; Xia,Ya-Nan; Liu,Bing-Yu; Jiang,Hai-Ying.
In the present study, a series of novel 5,7-diisoprenyloxyflavone derivatives were designed, synthesized, and evaluated for their antibacterial activity. Most of these compounds displayed significant antibacterial effects against Gram-positive bacteria, especially against strains of multidrug-resistant clinical isolates. Compounds 4c, 4g, 4i, 4j, 4k, 4l, 4n, 4q and 4t showed high levels of antimicrobial activity against Staphylococcus aureus RN4220 with minimum inhibitory concentrations of 4.0-20 µM. Compound 4k showed the most potent activity among these compounds against all multidrug-resistant clinical isolates tested. Unfortunately, none of the compounds were active against Gram-negative bacteria at the doses of 24-164 µM.
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Flavonoids; Synthesis; Isoprenyloxyflavones; Antibacterial activity.
Ano: 2020
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100541

Vasodilator activity of extracts of field Alpinia purpurata (Vieill) K: Schum and A. zerumbet (Pers.) Burtt et Smith cultured in vitro
Provedor de dados: 60
Autores: Victório,Cristiane Pimentel; Kuster,Ricardo Machado; Moura,Roberto Soares de; Lage,Celso Luiz Salgueiro.
Nowadays, the high blood pressure is one of the main causes of death and cardiovascular diseases. Vasodilator drugs are frequently used to treat arterial hypertension. Experiments were undertaken to determine whether hydroalcoholic extracts obtained from leaves of field-grown Alpinia purpurata and A. zerumbet cultured in vitro under different plant growth regulators induce a vasodilator effect on Wistar rat mesenteric vascular bed pre-contracted with norepinephrine. Plant extracts were able to induce a long-lasting endothelium-dependent vasodilation. Efficiency on activity of A. purpurata reached 87% at concentration of 60 μg. The extract of A. zerumbet maintained in medium containing IAA, induced the relaxation (17.4%) at 90 μg, as compared to the control...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Alpinia purpurata (Vieill) K. Schum./pharmacognosy; A. zerumbet (Pers.) Burtt et Smith./pharmacognosy; Natural vasodilators/experimental studies; Plant extracts/vasodilator action; Plant tissue/culture; Endothelium-dependent; Flavonoids; Medicinal Plant; Plant growth/regulators; Zingiberaceae.
Ano: 2009
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000300017

Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae)
Provedor de dados: 60
Autores: Cardoso,Claudia Andréa Lima; Coelho,Roberta Gomes; Honda,Neli Kika; Pott,Arnildo; Pavan,Fernando Rogério; Leite,Clarice Queico Fujimura.
Serjania erecta Radlk.(Sapindaceae) is a medicinal plant traditionally used in Brazil. We assayed the ethanolic extract of leaves and roots against seven microorganisms. The REMA (Resazurin Microtiter Assay) assay was used to measure the biological activity in vitro against Mycobacterium tuberculosis and our results showed moderate activity of the ethanolic extract. On the other hand S. aureus, P. aeruginosa, S. setubal, C. albicans, S. cerevisiae and E. coli revealed that the leaves and roots of S. erecta inhibited the growth of all microorganisms. The ethanolic extracts of leaves and roots showed low values of antioxidant activities. The ethanolic extracts of leaves and roots were analyzed by chromatographic and spectrometric methods. (-)-Epicatechin,...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Serjania erecta Radlk/pharmacognosy; Serjania erecta Radlk/ethanolic extract; Serjania erecta Radlk/antioxidant activity; Serjania erecta Radlk/ethanolic extract; Serjania erecta Radlk/antimicrobial activity; Sapindaceae/pharmacognosy; Cipó-cinco-folhas/pharmacognosy; Flavonoids; Medicinal plants.
Ano: 2013
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000400017

Anti-inflammatory activity and identification of the Verbena litoralis Kunth crude extract constituents
Provedor de dados: 60
Autores: Lima,Rachel de; Brondani,Juliana Calil; Dornelles,Rafaela Castro; Lhamas,Cibele Lima; Faccin,Henrique; Silva,Carine Viana; Dalmora,Sérgio Luiz; Manfron,Melânia Palermo.
Verbena litoralis is a plant popularly known as “gervãozinho-do-campo” in Portuguese. It is traditionally used for stomach, liver and gallbladder problems, and as an anti-inflammatory and anthelmintic. The goal of this study was to determine the chemical composition of the crude extract obtained from the aerial parts of V. litoralis by Ultra High Performance Liquid chromatography coupled with Mass Spectrometry in Tandem (UHPLC-MS/MS); assess the anti-inflammatory activity of ethyl acetate fraction and of crude extract; and verify liver, kidney and pancreas damage. In this study, the chemical composition of the extract was identified via UHPLC/MS/MS, assessing the anti-inflammatory activity of the crude extract and the acetate fraction in an induction model...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Verbena litoralis; UHPLC/MS; Flavonoids; Anti-inflammatory.
Ano: 2020
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100540

Phytochemical constituents and preliminary toxicity evaluation of leaves from Rourea induta Planch. (Connaraceae)
Provedor de dados: 60
Autores: Kalegari,Milena; Miguel,Marilis Dallarmi; Dias,Josiane de Fátima Gaspari; Lordello,Ana Luísa Lacava; Lima,Cristina Peitz de; Miyazaki,Cristina Mayumi Sasaki; Zanin,Sandra Maria Warumby; Verdam,Maria Christina dos Santos; Miguel,Obdulio Gomes.
Most active plants are toxic at high doses and it is therefore important to investigate the preliminary toxicity of plant extracts. The Rourea induta species is a potential drug with no phytochemical or biological studies registered in the literature. Thus, a phytochemical study and a toxicity analysis of the ethanolic extract obtained from the leaves of Rourea induta Planch., Connaraceae, was run. A long chain hydrocarbon, n-tetracosane, and four flavonoids were identified: quercetin, and three glycosylated derivates, quercetin-3-O-α-arabinofuranoside, quercetin-3-O-β-xyloside and quercetin-3-O-β-galactoside. This is the first time these have been isolated in this species. The structures were elucidated by 13C NMR, ¹H NMR, UV and IR spectroscopy. The...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Rourea induta/phytochemistry; Connaraceae/phytochemistry; Flavonoids; N-tetracosane; Plant extracts/toxicity.
Ano: 2011
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000300023

Extract of Solidago chilensis Meyen inflorescences: cytotoxicity and inhibitory activity on nitric oxide synthesis in activated macrophage cell line J774A.1
Provedor de dados: 60
Autores: Brito,Thais Morais de; Amendoeira,Fabio Coelho; Oliveira,Temistocles Barroso de; Frutuoso,Valber da Silva; Ferraris,Fausto Klabund; Valverde,Simone Sacramento.
Solidago chilensis Meyen (= Solidago microglossa) popularly known as “Brazilian arnica” is used to treat of inflammatory disorders. S. chilensis is constant in the Therapeutic Memento of the Rio de Janeiro city and belongs to the medicinal species of Brazilian National List of Medicinal Plants of Interest of the Unified National Health System (SUS). There are no studies in the literature showing the direct activity of this plant species on immune system cells. The present study evaluated the chemical composition as well as the cytotoxic and pharmacological activity of the ether-ethanol extract from S. chilensis inflorescences (SCIE) in murine macrophage cell line J774A.1. The results showed that higher concentrations (50 to 200 µg/mL) of SCIE had...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Anti-inflammatory activity; Medicinal plant; Asteraceae; Diterpenes; Flavonoids.
Ano: 2020
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100594

Development of enteric coated tablets from spray dried extract of feverfew (Tanacetum parthenium L: )
Provedor de dados: 60
Autores: Chaves,Juliana Siqueira; Da Costa,Fernando Batista; Freitas,Luís Alexandre Pedro de.
Tanacetum parthenium (feverfew) is an herb that is commercialized worldwide as a therapeutic treatment for migraine. Its pharmacological effect is mainly due to the presence of the sesquiterpene lactone parthenolide as well as of flavonoids. So far, there are no studies on standardization of pre-formulations or phytomedicines containing this herb. The present study aimed at developing a pre-formulation using a standardized spray-dried extract of feverfew and further designing and standardizing enteric coated tablets. In this work, the spray-dried extract of feverfew was evaluated for its parthenolide, santin and total flavonoid content, parthenolide solubility, particle size, tapped density, hygroscopicity, angle of repose and moisture content. Tablets...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Enteric coated tablets; Flavonoids; Parthenolide; Phytomedicine; Spray-dried extract; Tanacetum parthenium.
Ano: 2009
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000300024

Acetylcholinesterase inhibition, antioxidant and identification of some chemical constituents of Phyllanthus atropurpureus cultivated in Egypt
Provedor de dados: 60
Autores: Abdallah,Walid Elsayed; Elsayed,Wael Mohamady; Hassan,Rasmia Ali; Nazif,Naglaa Mohammed; Ali,Mohammed Ibrahim; Abdelshafeek,Khaled Abdelhady.
Investigation of the lipid constituents of the aerial parts of Phyllanthus atropurpureus resulted in isolation and identification of the fatty acid mixture which consists of eight acids with linolenic acid as major and the unsaponifiable fraction that contain a series of hydrocabons, sterols, in addition to one triterpene (α-amyrin). The acetone insoluble fraction was found to contain two fatty alcohols and three n-hydrocabons in which the n-eicosane is the most abundant (44.16%). The flavonoidal constituents were isolated from ethyl acetate and butanol fractions which were identified as: luteolin-7-O-glucoside, kaempferol 3-O-(p-coumaroylglucoside), kaempferitrin, luteolin and kaempferol. Evaluation of different extracts as acetylcholinesterase inhibitors...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Phyllanthus atropurpureus; Euphorbiaceae; Flavonoids; Acetylcholineesterase inhibitors; Antioxidant.
Ano: 2019
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100575

Phytochemical Evaluation of Wild and Cultivated Pepper (Capsicum annuum L. and C. pubescens Ruiz &amp;amp; Pav.) from Oaxaca, Mexico
Provedor de dados: 117
Autores: Vera-Guzmán,Araceli Minerva; Chávez-Servia,José Luis; Carrillo-Rodríguez,José Cruz; G. López,Mercedes.
Reports of the last decade show that some types of food and spices included in the human diet, such as pepper (Capsicum annuum L.) can have a positive effect on human health. The Mexican pepper germplasm is poorly documented with regard to variety and the amount of phytochemical compounds that it contains. In the present study, the variation of phytochemical compounds was evaluated in nine fruit variants (morphotypes) of wild and cultivated pepper grown in Oaxaca. ANOVA detected significant differences among pepper morphotypes and ripeness stages of fruits; vitamin C, total phenols, flavonoids, P-carotene, coordinated chromatic of color, and capsaicinoids. The highest values of vitamin C were found in 'Tabaquero', 'Guero' and 'Costeño' morphotypes (151.6...
Tipo: Journal article
Palavras-chave: Capsaicionids; Carotenoids; Phenols; Flavonoids; Vitamin C.
Ano: 2011
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-58392011000400013

The antioxidant properties of calafate (Berberis microphylla) fruits from four different locations in southern Chile
Provedor de dados: 118
Autores: Mariangel,Emilia; Reyes-Diaz,Marjorie; Lobos,Walter; Bensch,Emma; Schalchli,Heidi; Ibarra,Pamela.
The antioxidant capacity (AC), total anthocyanins (TA) and total phenols (TP) of calafate fruit from four locations in southern Chile (El Blanco, Lonquimay, Mañihuales and Temuco) were determined using both the free radical 2.2-diphenyl-1-picrylhydrazyl (DPPH) method and the linoleic acid oxidation inhibition method as well as the pH-differential and Folin-Ciocalteu methods. Phenolic compounds were also identified using HPLC-DAD (High Performance Liquid Chromatography-Diode-Array Detection). The results showed that TP varied significantly according to the location. Mañihuales was noteworthy, with 34.9 mg of GAE g-1 dried fruit. The measured AC level depended on the methodology used, varying significantly between locations according to the DPPH results....
Tipo: Journal article
Palavras-chave: Antioxidants; Antioxidant capacity; Berberis; Flavonoids; Phenolic acids; Total phenols.
Ano: 2013
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-16202013000100014

The medicinal value of honey: a review on its benefits to human health, with a special focus on its effects on glycemic regulation
Provedor de dados: 118
Autores: Cortés,Manuel E; Vigil,Pilar; Montenegro,Gloria.
Honey, a natural substance produced by honeybees, is composed of a complex mixture of carbohydrates, water, and a small amount of proteins, vitamins, minerals, and phenolic compounds. Fructose, glucose and maltose are among the various types of sugars present in honey. Used for millennia as both food and medicine, honey has been associated with improved antioxidant capacity, modulation of the immune system, antimicrobial activities, influence on lipid values (through antihypercholesterolemic effects) and regulation of glycemic responses, among other benefits. The aim of this article was to review the effects of natural honey intake on human health, with particular reference to its influence on glycemic regulation. Several studies have focused on the...
Tipo: Journal article
Palavras-chave: Diabetes; Flavonoids; Glycemic regulation; Honey; Insulin resistance; Nutraceuticals; Nutrition.
Ano: 2011
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-16202011000200015

The in vitro antifungal evaluation of a commercial extract of Chilean propolis against six fungi of agricultural importance
Provedor de dados: 118
Autores: Curifuta,Macarena; Vidal,Jorge; Sánchez-Venegas,Jaime; Contreras,Aliro; Salazar,Luis A; Alvear,Marysol.
Propolis has been used for millennia for its antimicrobial and pharmaceutical properties, whereas its use as an agricultural antifungal agent has only recently been assessed. The chemical characteristics of six ethanolic extracts of Chilean propolis (EEP-1 to EEP-6) were evaluated. The total polyphenols ranged between 7.8 and 42.3 mg mL-1 equivalents of a 2:1 pinocembrin: galangin standard, and the total flavonoid contents ranged between 4.0 and 19.7 mg mL-1 equivalents of quercetin. A high-performance liquid chromatographic (HPLC) analysis allowed the identification of caffeic acid, myricetin, quercetin, kaempferol, apigenin, pinocembrin, galangin, caffeic acid phenethyl ester (CAPE) and rutin. The EEP-3 extract was selected for additional studies based...
Tipo: Journal article
Palavras-chave: Alternaria alternata; Antifungal activity; Botrytis cinerea; Flavonoids; Fusarium sp.; Penicillium expansum; Polyphenols; Propolis.
Ano: 2012
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-16202012000200011

Different leaf extracts from Brunfelsia uniflora in mice
Provedor de dados: 65
Autores: Carvalho,Ciro José Sousa de; Melo,Marília Martins; Michell,Ana Flávia Ribeiro Machado; Torres,Bruno Benetti Junta; Riet-Correa,Franklin; Guedes,Roberto Maurício Carvalho; Ferraz,Vany Perpetua; Soto-Blanco,Benito; Silva,Silvana Maria Medeiros de Sousa.
ABSTRACT: In Brazil, at least 16 poisonous plant species can affect the central nervous system of livestock. Recently in the state of Piauí, Northeastern Brazil, Brunfelsia uniflora was reported as a cause of nervous signs in donkeys, cattle, and small ruminants. In order to assess the toxicity of B. uniflora extracts, 20 Swiss mice were distributed into four groups (n=5) receiving by gavage alkaloids, flavonoids, saponins, or saline (control group). After administration of the extracts in a single dose (5g kg-1), all mice were observed daily for clinical signs. Mice that received the extracts showed moderate to severe clinical signs, including piloerection, vocalization, and seizures. All mice dosed with saponins died between 10 and 20min after...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Toxicity; Alkaloids; Saponins; Flavonoids; Brunfelsia; Solanaceae.
Ano: 2018
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782018000100552

Antioxidant potential of various solvent extract from Morus alba fruits and its major polyphenols composition
Provedor de dados: 65
Autores: Kobus-Cisowska,Joanna; Szczepaniak,Oskar; Szymanowska-Powałowska,Daria; Piechocka,Justyna; Szulc,Piotr; Dziedziński,Marcin.
ABSTRACT:  Extraction conditions are an important factor in the process of obtaining bioactive compounds from plant matrix. These compounds differ structurally. Structures of phyto-compounds and their interactions with other food ingredient are not fully known, while these two aspects should play a significant role in extrahents choice and determination of extraction process conditions. Mulberry (Morus alba) is a plant growing in Asia, which fruits are rich in bioactive ingredients and high anti-oxidative potential. In our study we analyzed mulberry fruits extracts differing in the extra hent applied: acetone, methanol, ethanol and water. All tested extracts possessed rich polyphenolic composition and radical scavenging ability. The significant differences...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Morus alba; Antioxidants; Phenolic acids; Flavonoids.
Ano: 2020
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782020000100751

Domestic processing and storage on the physical-chemical characteristics of acerola juice (Malpighia glabra L.).
Provedor de dados: 64
Autores: Dala-Paula,Bruno Martins; Santos,Taís Pereira dos; Araújo,Laura de Souza; Bastos,Renata Rosane Andrade; Moraes,Juliana de Oliveira; Carbonera,Nádia.
ABSTRACT Acerola is a tropical fruit that stands out for its high content of ascorbic acid and phenolic compounds. However, there is currently a lack of information on the effects of the preparation and domestic storage of fruit juices, especially that of acerola. The objective of this work was to evaluate the effect of different liquefying times (10, 30 and 50 s) and cold storage at 4 °C for 0, 24, 48 and 72 h in domestic acerola juice. In relation to such, physicochemical determinations were performed, including pH, total titratable acidity, antioxidant potential, contents of phenolic compounds and total flavonoids in juices produced from the whole fruit, the pulp and acerola seed extracts. Whole fruit juice, liquefied for 10 s, had the highest pH and...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Antioxidant potential; Phenolic compounds; Flavonoids.
Ano: 2019
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-70542019000100405