Consulta: subjectFacets:"Gene sequencing"
Registros recuperados: 2
Data/hora: 01/06/2024 08:46:46

Development of a duplex Taqman real-time PCR assay for rapid identification of Vibrio splendidus -related and V. aestuarianus strains from bacterial cultures
Provedor de dados: 5
Autores: Saulnier, Denis; De Decker, Sophie; Tourbiez, Delphine; Travers, Marie-agnes.
To enable the rapid and accurate identification of Vibrio splendidus-related and V. aestuarianus strains associated with Pacific cupped oyster Crassostrea gigas mortality, we developed a duplex Taqman real-time PCR assay and evaluated its efficacy. This technique proved to be rapid, sensitive, and specific and will be particularly valuable for epidemiologic studies.
Tipo: Text
Palavras-chave: Multiplex real-time PCR; Gene sequencing; Molluscs; Splendidus Glade; Vibrio aestuarianus.
Ano: 2017
URL: http://archimer.ifremer.fr/doc/00392/50308/51077.pdf

A novel frameshift mutation of Chediak-Higashi syndrome and treatment in the accelerated phase
Provedor de dados: 56
Autores: Wu,X.L.; Zhao,X.Q.; Zhang,B.X.; Xuan,F.; Guo,H.M.; Ma,F.T.
Chediak-Higashi syndrome (CHS) is a rare autosomal recessive immunodeficiency disease characterized by frequent infections, hypopigmentation, progressive neurologic deterioration and hemophagocytic lymphohistiocytosis (HLH), known as the accelerated phase. There is little experience in the accelerated phase of CHS treatment worldwide. Here, we present a case of a 9-month-old boy with continuous high fever, hypopigmentation of the skin, enlarged lymph nodes, hepatosplenomegaly and lung infection. He was diagnosed with CHS by gene sequencing, and had entered the accelerated phase. After 8 weeks of therapy, the boy had remission and was prepared for allogenic stem cell transplantation.
Tipo: Info:eu-repo/semantics/report
Palavras-chave: Chediak-Higashi syndrome; Accelerated phase; Gene sequencing; Therapy.
Ano: 2017
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000400501