Consulta: subjectFacets:"Immune defense"
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Data/hora: 01/06/2024 05:34:09

Natural resistance to Fasciola hepatica (Trematoda) in Pseudosuccinea columella snails: A review from literature and insights from comparative “omic” analyses
Provedor de dados: 5
Autores: Alba, Annia; Tetreau, Guillaume; Chaparro, Cristian; Sánchez, Jorge; Vázquez, Antonio A.; Gourbal, Benjamin.
The snail Pseudosuccinea columella is one of the main vectors of the medically-important trematode Fasciola hepatica. In Cuba, the existence of natural P. columella populations that are either susceptible or resistant to F. hepatica infection offers a unique snail-parasite for study of parasite-host compatibility and immune function in gastropods. Here, we review all previous literature on this system and present new “omic” data that provide a molecular baseline of both P. columella phenotypes from naïve snails. Comparison of whole snail transcriptomes (RNAseq) and the proteomes of the albumen gland (2D-electrophoresis, MS) revealed that resistant and susceptible strains differed mainly in an enrichment of particular biological processes/functions and a...
Tipo: Text
Palavras-chave: Transcriptome; Albumen gland; Allocation of resources; Response to stress; Immune defense; Cost of resistance.
Ano: 2019
URL: https://archimer.ifremer.fr/doc/00509/62039/66180.pdf