Consulta: subjectFacets:"Immune system"
Registros recuperados: 28
Data/hora: 05/06/2024 08:07:46

Live yeasts in the gut: Natural occurrence, dietary introduction, and their effects on fish health and development
Provedor de dados: 5
Autores: Gatesoupe, Joel.
This minireview summarizes the present state of knowledge concerning the importance of yeasts in fish gut. Yeasts have been commonly isolated in the gastrointestinal tract, and high population densities were sometimes noted in healthy fish, but the data were quite variable in terms of colony counts and taxonomical diversity. Rhodotorula sp. seemed relatively frequent in both marine and freshwater fish, and Debaryomyces hansenii has been found to be dominant in rainbow trout. Some other dominant strains have been described, such as Metschnikowia zobelii, Trichosporon cutaneum, and Candida tropicalis in marine fish, and Candida sp., Saccharomyces cerevisiae, and Leucosporidium sp. in rainbow trout. The natural proliferation of yeasts in fish mucus may be...
Tipo: Text
Palavras-chave: Immune system; Growth promotion; Gut maturation; Gastrointestinal microbiota; Probiotics; Yeast.
Ano: 2007
URL: http://archimer.ifremer.fr/doc/2007/publication-2144.pdf

Why is Asari (= Manila) clam Ruditapes philippinarum fitness poor in Arcachon Bay: a meta-analysis to answer?
Provedor de dados: 5
Autores: De Montaudouin, X.; Lucia, M.; Binias, C.; Lassudrie, Malwenn; Baudrimont, M.; Legeay, A.; Raymond, N.; Jude-lemeilleur, F.; Lambert, C.; Le Goic, N.; Garabetian, F.; Gonzalez, P.; Hegaret, Helene; Lassus, Patrick; Mehdioub, W.; Bourasseau, L.; Daffe, G.; Paul-pont, I.; Plus, Martin; Do, V. T.; Meisterhans, G.; Mesmer-dudons, N.; Caill-milly, Nathalie; Sanchez, Florence; Soudant, P.
Asari (= Manila) clam, Ruditapes philippinarum, is the second bivalve mollusc in terms of production in the world and, in many coastal areas, can beget important socio-economic issues. In Europe, this species was introduced after 1973. In Arcachon Bay, after a decade of aquaculture attempt, Asari clam rapidly constituted neo-naturalized population which is now fished. However, recent studies emphasized the decline of population and individual performances. In the framework of a national project (REPAMEP), some elements of fitness, stressors and responses in Arcachon bay were measured and compared to international data (41 publications, 9 countries). The condition index (CI=flesh weight/shell weight) was the lowest among all compared sites. Variation in...
Tipo: Text
Palavras-chave: Ruditapes philippinarum; Condition index; Perkinsus; Brown Muscle Disease; Element contamination; Immune system; Arcachon Bay.
Ano: 2016
URL: https://archimer.ifremer.fr/doc/00280/39123/37676.pdf

Vitamin A supplementation enhances Senegalese sole (Solea senegalensis) early juvenile’s immunocompetence: new insights on potential underlying pathways
Provedor de dados: 5
Autores: Fernandez, Ignacio; Lopez-joven, Maria-carmen; Andree, Karl B.; Roque, Ana; Gisbert, Enric.
Senegalese sole (Solea senegalensis) has been considered since the 1990´s to be a promising flatfish species for diversifying European marine aquaculture. However, pathogen outbreaks leading to high mortality rates can impair Senegalese sole commercial production at the weaning phase. Different approaches have been shown to improve fish immunocompetence; with this in mind the objective of the work described herein was to determine whether increased levels of dietary vitamin A (VA) improve the immune response in early juveniles of Senegalese sole. For this purpose, Senegalese sole were reared and fed with Artemia metanauplii containing increased levels of VA (37,000; 44,666; 82,666 and 203,000 total VA IU Kg-1) from 6 to 60 days post-hatch (early juvenile...
Tipo: Text
Palavras-chave: Vitamin; Retinoic acid; Immune system; Gene expression; Senegalese sole Solea senegalensis; Photobacterium damselae subp. damselae.
Ano: 2015
URL: http://archimer.ifremer.fr/doc/00275/38617/37147.pdf

Influence of sulfur amino acid levels in diets of broiler chickens submitted to immune stress
Provedor de dados: 89
Autores: Rubin,LL; Ribeiro,AML; Canal,CW; Silva,IC; Trevizan,L; Vogt,LK; Pereira,RA; Lacerda,L.
Several changes in amino acid levels occur during an infection. As a rule, glycine, taurine and serine levels diminish considerably, while cysteine levels increase. Such changes may be attributed to the intense consumption of sulfur amino acids (SAA- methionine+cysteine) during infectious challenge. Methionine plays an important role in humoral and cellular immune responses. It has been suggested that such effect is exerted by intracellular glutathione and cysteine levels. Four-hundred thirty-two day-old Ross male broiler chickens were fed (from 1 to 42 days of age) three SAA levels in the diet (0.72, 0.82, and 0.92% from 1 to 21 days of age; 0.65, 0.75, and 0.85% from 22 to 42 days of age) and submitted to two immunological stimulus series. Vaccines...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Immune system; Immunological stimulus; Methionine; Performance; Poultry.
Ano: 2007
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2007000100008

Effects of Glycyrrhizic Acid on Productive and Immune Parameters of Broilers
Provedor de dados: 89
Autores: Ocampo,CL; Gómez-Verduzco,G; Tapia-Perez,G; Gutierrez,OL; Sumano,LH.
ABSTRACT Considering that glycyrrhizic acid (GRA) has been shown to have in-vitro and in-vivo antiviral activity against a wide range of viruses as well as immunostimulating activity, a trial to evaluate its effects on the performance and the immune response against Newcastle disease of broiler chickens was carried out. The study was performed with one-day-old Ross x Ross broiler chickens. GRA was added to the drinking water throughout the 49-d production cycle at a dose of 0.03%. Sample size of the trial was established in a pilot assay. Results showed that broiler chickens treated with GRA presented better weight gain, final body weight, feed conversion ratio, and lower mortality rate than the non-treated controls. In addition, GRA-treated birds...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Broiler chickens; Growth promotion; Immune system; Glycyrrhizic acid.
Ano: 2016
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2016000300435

Effects of methionine and arginine dietary levels on the immunity of broiler chickens submitted to immunological stimuli
Provedor de dados: 89
Autores: Rubin,LL; Canal,CW; Ribeiro,ALM; Kessler,A; Silva,I; Trevizan,L; Viola,T; Raber,M; Gonçalves,TA; Krás,R.
The present study aimed at assessing the effects of methionine and arginine on the immune response of broiler chickens submitted to immunological stimuli. Three methionine concentrations (0.31, 0.51, and 0.66% from 1 to 21 days of age; 0.29, 0.49, and 0.64% from 22 to 42 days of age) and 2 arginine concentrations (1.33 and 1.83%; 1.14 and 1.64% for the same life periods) were tested. Birds were divided into two groups for immunological stimuli (3x2x2 arrangement). Vaccines against Marek's disease, fowl pox, infectious bronchitis, Freund's Complete Adjuvant, Sheep red blood cells (SRBC), and avian tuberculin were administered to one group as immunological stimuli; the other group did not receive any stimulus. The experiment was carried out with 432...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Amino acids; Birds; Immune system; Vaccines.
Ano: 2007
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2007000400006

Hematological responses of tambaqui Colossoma macropomum (Serrassalmidae) fed with diets supplemented with essential oil from Mentha piperita (Lamiaceae) and challenged with Aeromonas hydrophila
Provedor de dados: 36
Autores: RIBEIRO,Suzana Cardoso; CASTELO,Antonielson Silva; SILVA,Bruna Marjara Picanço da; CUNHA,Andreza da Silva; PROIETTI JÚNIOR,Aldo Aparecido; OBA-YOSHIOKA,Eliane Tie.
ABSTRACTIn fish farmings, diseases can be reduced by using immunostimulants. The aim of this study was to evaluate the immunostimulant potential of Mentha piperita in tambaqui fed with 0, 0.5, 1.0 and 1.5% of oil per kg of commercial fish feed. The fish were inoculated with Aeromonas hydrophila to challenge them. Hematological and biochemical parameters were determined after 30 days of feeding and seven days after the challenge. There was no mortality and M. piperita oil did not influence fish production parameters. However, blood hemoglobin concentration (Hb) increased in the fish fed with 0.5 and 1.5% of oil per kg of diet; albumin increased in those fed with 1.0%; cholesterol increased in all groups with oil; and triglycerides increased in those fed...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Immune system; Natural product; Bacterial challenge; Biochemistry.
Ano: 2016
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672016000100099

ANTIMICROBIAL PEPTIDES, AN ALTERNATIVE TO COMBAT BACTERIAL RESISTANCE
Provedor de dados: 37
Autores: MEJÍA-ARGUETA,Euridice Ladisu; SANTILLÁN-BENÍTEZ,Jonnathan Guadalupe; ORTIZ-REYNOSO,Mariana.
ABSTRACT Antimicrobial peptides (AMPs) of higher organisms have been studied for the past 25 years, and their importance as components of innate immunity is now well established. The essential simplicity of their chemical structure, along with the lower likelihood of developed resistance compared to conventional antibiotics, has made them attractive candidates for development as therapeutics. The objective of this review article is to describe the current relevance, main mechanisms presented, and the uses of antimicrobial peptides as new therapies in the clinical area. The information used was mainly compiled from scientific articles based on a systematic review of scientific papers with data on human AMPs and their different applications, searching...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Antimicrobial potential; Immune system; Therapeutic agents.
Ano: 2020
URL: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0120-548X2020000200294

Avaliação da arginina dietética sobre a resposta imunológica de frangos de corte imunizados contra a Doença de Gumboro - doi: 10.4025/actascianimsci.v33i2.9738
Provedor de dados: 2
Autores: Fernandes, Jovanir Inês Müller; Universidade Federal do Paraná; Rosa, Daniela Dalla; UFPR - Palotina; Ribeiro, Mayra Vissotto; UFPR-Palotina; Lima, Edna Tereza de; UFPR - Palotina; Fernandes, Nelson Luis Mello; UFPR - Palotina.
O estudo foi realizado com o objetivo de avaliar o efeito da suplementação de Arginina (Arg) sobre a resposta imune humoral e o desenvolvimento dos órgãos linfoides de frangos de corte imunizados contra a Doença de Gumboro. Foram utilizados 640 pintos de corte, distribuídos aleatoriamente em um delineamento inteiramente casualizado com quatro tratamentos (1. Controle, 2. Imunização, 3. Imunização + suplementação de L-Arg e 4. Suplementação de L-Arg.) e oito repetições de 20 aves cada. As aves dos tratamentos 3 e 4 foram imunizadas no 16&amp;deg; dia, contra a Doença de Gumboro (cepa intermediária plus). Amostras de soro das aves com 14, 21, 28 e 35 dias de idade foram analisadas por ELISA para detecção de título de anticorpos contra a Doença de Gumboro e...
Tipo: Pesquisa de campo
Palavras-chave: 5.04.03.01-0 Aminoácido; Doença infecciosa da Bursa de Fabrício; Sistema imune; Título de anticorpos; Bolsa cloacal Nutrição animal amino acid; Infectious bursal disease; Immune system; Antibody titers; Cloacal bursa.
Ano: 2011
URL: http://periodicos.uem.br/ojs/index.php/ActaSciAnimSci/article/view/9738

Arginine metabolism in uricotelic species - doi: 10.4025/actascianimsci.v32i4.10990
Provedor de dados: 2
Autores: Fernandes, Jovanir Inês Müller; Universidade Federal do Paraná; Murakami, Alice Eiko; UEM.
Due to the lack of a complete urea cycle, uricotelic species, such as broilers, are not able to synthesize de novo arginine (Arg), thus depending exclusively on dietary Arg. High levels of dietary lysine (Lys) increase the demand for Arg because of the antagonistic relationship between these amino acids. The Arg-Lys antagonism promotes an expressive increase in the renal Arg activity and consequently induces the degradation of Arg and the decrease in the activity of glycine amidinotransferase, an enzyme that uses Arg in the synthesis of muscle creatin. Arg is considered an important modulator of immunological and physiological processes. The degradation of Arg produces ornithine, a precursor of polyamines that are key to cell division, DNA synthesis, and...
Palavras-chave: Carbamoyl phosphatase synthetase; Creatine; Immune system; Nitric oxide; Polyamines; Urea cycle carbamoyl phosphatase synthetase; Creatine; Immune system; Nitric oxide; Polyamines; Urea cycle.
Ano: 2010
URL: http://periodicos.uem.br/ojs/index.php/ActaSciAnimSci/article/view/10990

Ontogenic development of kidney, thymus and spleen and phenotypic expression of CD3 and CD4 receptors on the lymphocytes of cobia (Rachycentroncanadum )
Provedor de dados: 42
Autores: KLOSTERHOFF,MARTA C.; PEREIRA JÚNIOR,JOABER; RODRIGUES,RICARDO V.; GUSMÃO,EMELINE P.; SAMPAIO,LUÍS A.; TESSER,MARCELO B.; ROMANO,LUIS A.
ABSTRACT In the present study was evaluated the ontogenic of immunocompetent organs of cobia up to 53 days after hatching (dah) through histology and immunohistochemistry techniques. The kidney was the first lymphohematopoietic organ to appear, at 1 dah, followed by the spleen at 5 dah and the thymus at 7 dah. The first CD3 receptors on the lymphocytes were observed in 27% of the thymic tissue at 7 dah and in 99% at 53 dah. The phenotypic expression of CD3 receptors was registered in 10% of the kidney at 8 dah and in 32% at 53 dah. CD4 receptors were observed in 5% and 63% of the thymic area at 7 and 53 dah, respectively. In the kidney, T4 lymphocytes were first observed at 13 dah in 9% of the organ and in 28% at 53 dah, defining the functional development...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Cobia; Immune system; Ontogeny; Immunohistochemistry; Lymphoid organs.
Ano: 2015
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000502111

Hematological and immunological development from birth to six months of age in Holstein calves
Provedor de dados: 45
Autores: Baccili,C.C.; Oliveira,S.M.F.N. de; Costa,J.F.R; Massoco,C.O.; Pozzi,C.R.; Gomes,V.
ABSTRACT The hematological and immunological development of calves from birth to 6 months of age was performed by hemogram and cellular phenotype. Ten male Holstein calves were assessed in 13 moments: before colostrum intake (D0), every 2 days until the 10th day of life (D2 to D10), at the 15th day after birth (D15), and then monthly up to 6 months (D180). Calves presented hemoconcentration on day (D) 0 and showed a gradual decrease in hematimetric rates until D180. The inversion of the neutrophilic for lymphocytic profile was observed on D4. The percentage of CD3+ cells on D10 was higher than D30 up to D180. The number of CD4+ and CD8+ cells did not change between time points. The number of CD21+ lymphocytes was significantly higher at early time points...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Bovine; Immune system; Leukogram; Immunophenotyping; Flow cytometry.
Ano: 2018
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352018000601823

The effects of nitric oxide on the immune response during giardiasis
Provedor de dados: 55
Autores: Pavanelli,Wander Rogério; Gutierrez,Fredy Roberto Salazar; Silva,Jean Jerley Nogueira da; Costa,Ivete Conchon; Menezes,Maria Claudia Noronha Dutra de; Oliveira,Francisco José de Abreu; Itano,Eiko Nakagawa; Watanabe,Maria Angélica Ehara.
Nitric oxide (NO) is a free radical synthesized from L-arginine by different isoforms NO-synthases. NO possesses multiple and complex biological functions. NO is an important mediator of homeostasis, and changes in its generation or actions can contribute or not to pathological states. The knowledge of effects of NO has been not only important to our understanding of immune response, but also to new tools for research and treatment of various diseases. Knowing the importance of NO as inflammatory mediator in diverse infectious diseases, we decided to develop a revision that shows the participation/effect of this mediator in immune response induced against Giardia spp. Several studies already demonstrated the participation of NO with microbicidal and...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Nitric oxide; Immune system; Giardiasis.
Ano: 2010
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000600010

Effect of fatty acids on leukocyte function
Provedor de dados: 56
Autores: Pompéia,C.; Lopes,L.R.; Miyasaka,C.K.; Procópio,J.; Sannomiya,P.; Curi,R.
Fatty acids have various effects on immune and inflammatory responses, acting as intracellular and intercellular mediators. Polyunsaturated fatty acids (PUFAs) of the omega-3 family have overall suppressive effects, inhibiting lymphocyte proliferation, antibody and cytokine production, adhesion molecule expression, natural killer cell activity and triggering cell death. The omega-6 PUFAs have both inhibitory and stimulatory effects. The most studied of these is arachidonic acid that can be oxidized to eicosanoids, such as prostaglandins, leukotrienes and thromboxanes, all of which are potent mediators of inflammation. Nevertheless, it has been found that many of the effects of PUFA on immune and inflammatory responses are not dependent on eicosanoid...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Fatty acids; Immune system; Inflammation; Dietary lipids; Leukocytes.
Ano: 2000
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000001100001

The conservative physiology of the immune system
Provedor de dados: 56
Autores: Vaz,N.M.; Faria,A.M.C. de; Verdolin,B.A.; Silva Neto,A.F.; Menezes,J.S.; Carvalho,C.R.
Current immunological opinion disdains the necessity to define global interconnections between lymphocytes and regards natural autoantibodies and autoreactive T cells as intrinsically pathogenic. Immunological theories address the recognition of foreignness by independent clones of lymphocytes, not the relations among lymphocytes or between lymphocytes and the organism. However, although extremely variable in cellular/molecular composition, the immune system preserves as invariant a set of essential relations among its components and constantly enacts contacts with the organism of which it is a component. These invariant relations are reflected, for example, in the life-long stability of profiles of reactivity of immunoglobulins formed by normal organisms...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Immunobiology; Immune system; Closure; Network; Autopoiesis; Panama blot.
Ano: 2003
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000100003

Treatment of hemorrhagic shock with hypertonic saline solution modulates the inflammatory response to live bacteria in lungs
Provedor de dados: 56
Autores: Fernandes,C.I.; Llimona,F.; Godoy,L.C.; Negri,E.M.; Pontieri,V.; Moretti,A.I.; Fernandes,T.R.; Soriano,F.G.; Velasco,I.T.; Souza,H.P.
Shock and resuscitation render patients more susceptible to acute lung injury due to an exacerbated immune response to subsequent inflammatory stimuli. To study the role of innate immunity in this situation, we investigated acute lung injury in an experimental model of ischemia-reperfusion (I-R) followed by an early challenge with live bacteria. Conscious rats (N = 8 in each group) were submitted to controlled hemorrhage and resuscitated with isotonic saline (SS, 0.9% NaCl) or hypertonic saline (HS, 7.5% NaCl) solution, followed by intratracheal or intraperitoneal inoculation of Escherichia coli. After infection, toll-like receptor (TLR) 2 and 4 mRNA expression was monitored by RT-PCR in infected tissues. Plasma levels of tumor necrosis factor α and...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Toll-like receptors; Immune system; Pneumonia; Escherichia coli; Neutrophils.
Ano: 2009
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009001000004

Immunological effects of donor lymphocyte infusion in patients with chronic myelogenous leukemia relapsing after bone marrow transplantation
Provedor de dados: 56
Autores: Castro,F.A.; Palma,P.V.B.; Morais,F.R.; Voltarelli,J.C.
Allogeneic bone marrow transplantation (alloBMT) is the only curative therapy for chronic myelogenous leukemia (CML). This success is explained by the delivery of high doses of antineoplastic agents followed by the rescue of marrow function and the induction of graft-versus-leukemia reaction mediated by allogeneic lymphocytes against host tumor cells. This reaction can also be induced by donor lymphocyte infusion (DLI) producing remission in most patients with CML who relapse after alloBMT. The immunological mechanisms involved in DLI therapy are poorly understood. We studied five CML patients in the chronic phase, who received DLI after relapsing from an HLA-identical BMT. Using flow cytometry we evaluated cellular activation and apoptosis, NK...
Tipo: Info:eu-repo/semantics/other
Palavras-chave: Chronic myelogenous leukemia; Donor lymphocyte infusion; Immune system; Bone marrow transplantation.
Ano: 2004
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000200006

Immunoregulatory and anti-inflammatory effects of n-3 polyunsaturated fatty acids
Provedor de dados: 56
Autores: Calder,P.C.
1. Fish oils are rich in the long-chain n-3 polyunsaturated fatty acids (PUFAs), eicosapentaenoic (20:5n-3) and docosahexaenoic (22:6n-3) acids. Linseed oil and green plant tissues are rich in the precursor fatty acid, &lt;FONT FACE="Symbol"&gt;a&lt;/font&gt;-linolenic acid (18:3n-3). Most vegetable oils are rich in the n-6 PUFA linoleic acid (18:2n-6), the precursor of arachidonic acid (20:4n-6). 2. Arachidonic acid-derived eicosanoids such as prostaglandin E2 are pro-inflammatory and regulate the functions of cells of the immune system. Consumption of fish oils leads to replacement of arachidonic acid in cell membranes by eicosapentaenoic acid. This changes the amount and alters the balance of eicosanoids produced. 3. Consumption of fish oils diminishes...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Lymphocyte; Macrophage; Immune system; Inflammation; Fish oil; Polyunsaturated fatty acid; Cytokine; Eicosanoid.
Ano: 1998
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000400002

Effects of diazepam on Mycobacterium bovis-induced infection in hamsters
Provedor de dados: 56
Autores: Righi,D.A.; Pinheiro,S.R.; Guerra,J.L.; Palermo-Neto,J.
The in utero exposure of hamsters to low doses of diazepam results in impaired host defense against Mycobacterium bovis during adulthood. Delayed developmental immunotoxicity, however, represents a specific situation that might not be general. The present experiment was undertaken to investigate the effects of diazepam on hamster resistance to M. bovis using adult animals. The effects of diazepam treatment on serum cortisol levels were also studied. Adult hamsters (N = 10 for each group) were treated with diazepam (E1 = 1.0, E2 = 2.0 or E3 = 3.0 mg kg-1 day-1 subcutaneously) or with control solution (C) for 30 days. Seven days after the beginning of the treatment, the animals received identical inoculum concentrations of M. bovis. Hamsters treated with the...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Mycobacterium bovis; Host resistance; Macrophages; Diazepam; Immune system.
Ano: 1999
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000900014

The neuroimmune-endocrine axis: pathophysiological implications for the central nervous system cytokines and hypothalamus-pituitary-adrenal hormone dynamics
Provedor de dados: 56
Autores: Licinio,J.; Frost,P.
Cytokines are molecules that were initially discovered in the immune system as mediators of communication between various types of immune cells. However, it soon became evident that cytokines exert profound effects on key functions of the central nervous system, such as food intake, fever, neuroendocrine regulation, long-term potentiation, and behavior. In the 80's and 90's our group and others discovered that the genes encoding various cytokines and their receptors are expressed in vascular, glial, and neuronal structures of the adult brain. Most cytokines act through cell surface receptors that have one transmembrane domain and which transduce a signal through the JAK/STAT pathway. Of particular physiological and pathophysiological relevance is the fact...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Central nervous system; Cytokines; Immune system; Neuroendocrine regulation; Fever; Food intake.
Ano: 2000
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000001000003

Effects of natural aging and gender on pro-inflammatory markers
Provedor de dados: 56
Autores: Milan-Mattos,J.C.; Anibal,F.F.; Perseguini,N.M.; Minatel,V.; Rehder-Santos,P.; Castro,C.A.; Vasilceac,F.A.; Mattiello,S.M.; Faccioli,L.H.; Catai,A.M.
The term inflammaging is now widely used to designate the inflammatory process of natural aging. During this process, cytokine balance is altered, presumably due to the loss of homeostasis, thus contributing to a greater predisposition to disease and exacerbation of chronic diseases. The aim of the study was to analyze the relationship between pro-inflammatory markers and age in the natural aging process of healthy individuals. One hundred and ten subjects were divided into 5 groups according to age (22 subjects/group). Interleukin-6 (IL-6) and tumor necrosis factor α (TNF-α) were quantified using the ELISA method. High-sensitivity C-reactive protein (hsCRP) was analyzed by turbidimetry according to laboratory procedures. The main findings of this study...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Natural aging; Inflammaging; Immune system; HsCRP; IL-6.
Ano: 2019
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000900601

Gap junctions in the cardiovascular and immune systems
Provedor de dados: 56
Autores: Rozental,R.; Campos-de-Carvalho,A.C.; Spray,D.C.
Gap junctions are clusters of intercellular channels directly connecting the cytoplasm of adjacent cells. These channels are formed by proteins named connexins and are present in all metazoan organisms where they serve diverse functions ranging from control of cell growth and differentiation to electric conduction in excitable tissues. In this overview we describe the presence of connexins in the cardiovascular and lympho-hematopoietic systems giving the reader a summary of the topics to be covered throughout this edition and a historical perspective of the discovery of gap junctions in the immune system.
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Gap junctions; Cardiovascular system; Immune system; Connexins.
Ano: 2000
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000400001

Evolution and conservation of immunological activity
Provedor de dados: 56
Autores: Vaz,N.M.
Paraphrasing what Gregory Bateson says on evolution, we might say that: "Immunology has long been badly taught. In particular, students - and even professional immunologists - acquire theories of immunological activity without any deep understanding of what problems these theories attempt to solve."
Tipo: Info:eu-repo/semantics/other
Palavras-chave: Theory; Immune system; Evolution; Conservation; Bateson; Maturana.
Ano: 2006
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006001200002

Glycoconjugates and polysaccharides of fungal cell wall and activation of immune system
Provedor de dados: 58
Autores: Pinto,M.R.; Barreto-Bergter,E.; Taborda,C.P.
The fate of organochlorine 14C-dicofol in activated sludge process was investigated. Results showed that the major part of radioactivity remained adsorbed on biological sludge. Consequently, its final disposal deserves special attention. The small amounts of dicofol, biotransformed or not, which remained in the treated effluent could contaminate receiving bodies.
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Glycoproteins; Polysaccharides; Glycosphingolipids; Immune system; Fungi.
Ano: 2008
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822008000200001

Regulation of T lymphocyte subpopulations in specific pathogen-free chickens following experimental fowl adenovirus-Ⅷinfection
Provedor de dados: 58
Autores: Wang,Chun-jie; Yu,Siriguleng; Ao-ri-ge-le,; Jia,De-gang; Yao,Hong-qiang; Zhao,Huai-ping; Lillehoj,H.S.; Si-mu-ji-de,; Postnikoff,Andrew CL; Xu,Si-ri-gu-leng.
Two-day-old specific pathogen-free (SPF) chickens were divided into two groups. Group I was inoculated orally with fowl adenovirus VIII (FAV-VIII). Group II served as a negative control. Chickens were investigated at various days post-inoculation (dpi) by flow cytometric analysis for changes in T lymphocyte subpopulations in immune system and blood. In the thymus, CD3+ T lymphocytes were increased at 25 dpi, with significant increases in the FAV infected noted at 1, 12, 20dpi (p&lt;0.05). This was accompanied by a corresponding increase of CD4+ and CD8+ T lymphocytes. In the spleen, CD3+ and CD4+ T lymphocytes were increased significantly at 30 dpi (p&lt;0.01) whereas CD8+ and TCR γ δ+ T lymphocytes were decreased at 1 (p&lt;0.05), 30 dpi (p&lt;0.01). An...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Cell mediated immune competency; Fowl adenovirus VIII; Immune system; Peripheral blood; T lymphocyte subpopulations.
Ano: 2012
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822012000400007

Up-regulation of human immune system function by Donkey’s Milk
Provedor de dados: 60
Autores: Taghiloo,Saeid; Allahmoradi,Esmaeil; Sadeghian-Kiadehi,Seyedeh Forough; Omrani-Nava,Versa; Nazar,Eisa; Ebrahimzadeh,Mohammad Ali.
Donkey’s milk represents a good alternative to human milk because of its chemical characteristics similar to those of human’s. In present study, the pro- and anti-inflammatory effects of donkey’s milk were evaluated on peripheral blood mononuclear cells (PBMCs). PBMCs were isolated from 12 young and 12 aged normal subjects. PBMCs were cultured with or without the optimal and non-cytotoxic dose of pasteurized donkey’s milk, and polymyxin B was used to inhibit the possible endotoxin contamination. Following 18 hours incubation, culture supernatants were harvested to measure the secreted Tumor necrosis factor-α (TNF-α), Interleukin-6 (IL-6), Interleukin-8 (IL-8) and Interleukin-10 (IL-10) by ELISA. Donkey’s milk significantly increased TNF-α (p= 0.01), IL-8...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Donkey’s milk; ELISA; Immune system; Aged subject; Cytokine.
Ano: 2020
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100607

Hematology and serum biochemistry of broilers at the initial and growth stages submitted to different levels of digestible sulfur amino acids
Provedor de dados: 65
Autores: Carvalho,Genilson Bezerra de; Martins,Poliana Carneiro; Rezende,Pedro Moraes; Santos,Januária Silva; Oliveira,Evelyn de; Trentin,Thays de Campos; Martins,Danieli Brolo; Stringhini,José Henrique; Café,Marcos Barcellos.
ABSTRACT: The objective of this study was to evaluate the effect of digestible methionine and cystine (Met + Cys) levels on the hematological and serum biochemical parameters of broiler chickens during the initial and growth stages. For this, 1,800 male chicks of the Coob 500 strain were used, with 900 chicks in the initial phase (1 to 21 days old) and 900 chicks in the growth phase (22 to 42 days old), distributed in a completely randomized design of five treatments with six replicates of 30 birds. The treatments consisted of 0.545, 0.616, 0.711, 0.782, and 0.853%; and 0.514, 0.571, 0.647, 0.704, and 0.761% digestible Met + Cys for “1 to 21” and “22 to 42” days of breeding, respectively. Results showed that digestible Met + Cys levels in broiler feed...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Amino acid metabolism; Cysteine; Methionine; Immune system; Poultry.
Ano: 2020
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782020000500652

Broiler adaptation to post-hatching period
Provedor de dados: 65
Autores: Maiorka,Alex; Dahlke,Fabiano; Morgulis,Maria Silvia Furquim de Azevedo.
In the latest years more attention has been given to mechanisms for bird adaptation at post-hatching period by management of environmental conditions and formulations of diets offered during this period when digestive, immune, and thermo-regulating systems suffer slight changes. In post-hatching period, digestive system is anatomically complete, but its functionality is still immature in relation to adult birds. The chick immunity depends on maternal antibodies transferred to egg just before laying. In addition, variations within thermal comfort zone might affect initial development of chick. For example, high temperatures may induce hyperthermia with dehydration, while low temperatures may lead to hypothermia responsible by pulmonary hypertension...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Broiler; Digestive system; Immune system; Thermo-regulatory system.
Ano: 2006
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782006000200057