Consulta: subjectFacets:"Leiomyoma"
Registros recuperados: 5
Data/hora: 06/06/2024 06:13:44

Cytochrome P450c17alpha (CYP17) gene polymorphism is not associated with leiomyoma susceptibility
Provedor de dados: 74
Autores: Yao-Yuan,Hsieh; Fuu-Jen,Tsai; Chi-Chen,Chang; Chang-Hai,Tsai; Cheng-Chieh,Lin; Lian-Shun,Yeh.
Estrogen plays a role in the pathogenesis of leiomyoma. The CYP17 gene codes for the cytochrome P450c17alpha enzyme, which is involved in the biosynthesis of estrogen. Our aim was to investigate if CYP17 polymorphism could be a useful marker to predict the susceptibility to leiomyoma. Our sample of female subjects was divided into two groups: (1) with leiomyoma (n = 159); (2) without leiomyoma (n = 128). A 169-bp fragment encompassing the A1/A2 polymorphic site of the CYP17 gene was amplified by polymerase chain reaction (PCR), restricted by enzyme MspA1I and electrophored on agarose gel. Genotypes and allelic frequencies for this polymorphism in both groups were compared. There was no significant difference between the two groups regarding the...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Cytochrome P450c17; CYP17; Leiomyoma; Single nucleotide polymorphism.
Ano: 2002
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572002000400002

The contribution of imaging in the diagnosis of endotracheal tumors in dogs: case report
Provedor de dados: 195
Autores: Zakimi, Renata Fenuchi dos Santos; Silva, Tatiane Marchetti da; Kirchheimer, Vinicius; Alves, Jefferson Douglas Soares; Abreu, Rogério Navarro de.
The trachea is a tubular structure that extends from the body of the axis to the fifth thoracic vertebra, where it then branches in the main bronchi, on the base of the heart. Although rare in dogs and cats, there are reports of intraluminal tracheal mass, either non-neoplastic, benign, or neoplastic malignant masses, which may even cause dynamic obstruction of the trachea. Radiography is a very useful technique for identifying and defining lower respiratory tract disease, including contrasting techniques that delineate the trachea. In this case report, a female dog of the Great Dane breed, two years old, was treated for a chest x-ray, whose main complaint was severe cough. Simple and contrasted radiographs were performed, where it was possible to observe...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Dog; Leiomyoma; Tracheobronchoscopy; Tracheal tumor cão; Leiomioma; Traqueobroncoscopia; Tumor traqueal.
Ano: 2017
URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/37334

Antioxidant status in women with uterine leiomyoma: relation with sex hormones
Provedor de dados: 42
Autores: PEJIĆ,SNEŽANA; TODOROVIĆ,ANA; STOJILJKOVIĆ,VESNA; GAVRILOVIĆ,LJUBICA; POPOVIĆ,NATAŠA; PAJOVIĆ,SNEŽANA B.
ABSTRACTUterine leiomyomas are benign soft-tissues tumors that arise from uterine smooth muscle tissue. Etiopathogenesis of leiomyomas is not well understood. We aimed to examine whether antioxidant enzyme activities and lipid hydroperoxides level in patients with leiomyoma are influenced by changes in sex hormones and gonadotropins (estradiol (E2), progesterone, FSH, and LH) during menstrual cycle and in postmenopause. The material consisted of blood and uterine tissue specimens. Hormone concentrations were determined and assays for superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase activities and lipid hydroperoxides concentration were performed. In blood of examined women, a significant difference in catalase, glutathione...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Antioxidant enzymes; Lipid hydroperoxides; Sex steroids; Leiomyoma.
Ano: 2015
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000401771

Uterine leiomyoma in chimpanzee (Pan troglodytes)
Provedor de dados: 45
Autores: Silva,A.E.; Ocarino,N.M.; Cassali,G.D.; Nascimento,E.F.; Coradini,M.A.; Serakides,R.
Uma chimpanzé de 22 anos de idade foi necropsiada com histórico clínico de anorexia, vômitos freqüentes e desidratação conseqüentes à gastrite iatrogênica. Macroscopicamente, o útero apresentava-se aumentado de volume, com o lúmen totalmente ocluído por nódulos firmes, esbranquiçados e coalescentes que se estendiam para o miométrio. Histologicamente, os nódulos eram constituídos por leiomiócitos bem diferenciados dispostos em várias direções e com coloração característica pelo tricrômio de Gomori e Masson. Pela imunoistoquímica, as células neoplásicas apresentavam marcação forte e difusa de receptores para progesterona e estrógeno, assim como de actina alfa de músculo liso. Algumas células neoplásicas e o estroma apresentavam marcação para vimentina e...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Chimpanzee; Uterus; Leiomyoma; Immunohistochemical.
Ano: 2006
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352006000100020

Galactosaminoglycans from normal myometrium and leiomyoma
Provedor de dados: 56
Autores: Berto,A.G.A.; Oba,S.M.; Michelacci,Y.M.; Sampaio,L.O.
In many tumors, the amount of chondroitin sulfate in the extracellular matrix has been shown to be elevated when compared to the corresponding normal tissue. Nevertheless, the degree of chondroitin sulfate increase varies widely. In order to investigate a possible correlation between the amount of chondroitin sulfate and tumor size, several individual specimens of human leiomyoma, a benign uterine tumor, were analyzed. The glycosaminoglycans from eight tumors were extracted and compared with those from the respective adjacent normal myometrium. The main glycosaminoglycan found in normal myometrium was dermatan sulfate, with small amounts of chondroitin sulfate and heparan sulfate. In leiomyoma, both dermatan sulfate and chondroitin sulfate were detected...
Tipo: Info:eu-repo/semantics/other
Palavras-chave: Galactosaminoglycan; Glycosaminoglycan; Chondroitin sulfate; Dermatan sulfate; Leiomyoma; Myometrium.
Ano: 2001
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000500011