Consulta: subjectFacets:"Leishmania chagasi"
Registros recuperados: 7
Data/hora: 11/06/2024 17:32:05

Inflammatory response, parasite load and AgNOR expression in ear skin of symptomatic and asymptomatic Leishmania (Leishmania) chagasi infected dogs
Provedor de dados: 80
Autores: BLA,Verçosa; ACJ,Borges; FJM,Mendes; MLS,Costa; NB,Pereira; MN,Melo; IL,Mendonça; FAL,Costa; AC,Vasconcelos.
The skin has an important role in the transmission of visceral leishmaniasis (VL) as the infection pathway in dogs. To better characterize the inflammatory response of intact skin in VL, sixty infected dogs (30 symptomatic and 30 asymptomatic) and six non-infected controls were studied. Diagnosis of visceral leishmaniasis was confirmed by RIFI and ELISA; direct visualization of the parasite in bone marrow aspirate; imprints of popliteal lymph nodes, spleen, liver and skin; culture in NNN-phase liquid Schneider's medium; and PCR (performed only in the ear skin). Amastigote forms of the parasite in intact skin were found only in symptomatic dogs. Inflammatory infiltrates were observed in all groups, varying from intense and/or moderate in symptomatic to...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Visceral leishmaniasis; Inflammation; Parasites; Leishmania chagasi.
Ano: 2011
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000300011

Molecular detection ofLeishmaniaspp. in road-killed wild mammals in the Central Western area of the State of São Paulo, Brazil
Provedor de dados: 80
Autores: Richini-Pereira,Virginia Bodelão; Marson,Pamela Merlo; Hayasaka,Enio Yoshinori; Victoria,Cassiano; Silva,Rodrigo Costa da; Langoni,Hélio.
Background Road-killed wild animals have been classified as sentinels for detecting such zoonotic pathogens asLeishmaniaspp., offering new opportunities for epidemiological studies of this infection.Methods This study aimed to evaluate the presence ofLeishmaniaspp. andLeishmania chagasiDNA by PCR in tissue samples (lung, liver, spleen, kidney, heart, mesenteric lymph node and adrenal gland) from 70 road-killed wild animals.Results DNA was detected in tissues of oneCavia aperea(Brazilian guinea pig), fiveCerdocyon thous(crab-eating fox), oneDasypus septemcinctus(seven-banded armadillo), twoDidelphis albiventris(white-eared opossum), oneHydrochoerus hydrochoeris(capybara), twoMyrmecophaga tridactyla(giant anteater), oneProcyon cancrivorus(crab-eating...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Road-killed animal; Leishmaniaspp; Leishmania chagasi; PCR; Zoonosis.
Ano: 2014
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992014000200331

Alterações séricas do metabolismo do ferro em cães com leishmaniose visceral canina
Provedor de dados: 195
Autores: Albano, Sandra Geisa Costa; Machado, Luciana Pereira; Santos, Railson Sousa; Lisboa Neto, Antônio Francisco; dos Santos, Jamile Prado; Biagiotti, Daniel.
Foi avaliado o efeito da leishmaniose visceral canina (LVC) nos parâmetros séricos do metabolismo do ferro. Foram utilizados 30 cães residentes no município de Bom Jesus–PI, divididos em três grupos de dez animais: G1(cães positivos para LVC no exame parasitológico); G2 (cães inicialmente com suspeita clínica de LVC, porém negativos no exame sorológico e parasitológico) e; G3 grupo controle (cães sem alterações clínicas e sorologia negativa para LVC). Foram colhidos 5ml de sangue por punção da veia jugular em tubos contendo anticoagulante EDTA para avaliação do hemograma e 10ml de sangue em tubos sem anticoagulante, para avaliados da concentração sérica do ferro, capacidade total (CTLF) e latente de ligação do ferro (CLLF) e do índice de saturação da...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Leishmania chagasi; Transferrina; Anemia.
Ano: 2013
URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/22159

Susceptible hosts: a resort for parasites right in the eye of the immune response
Provedor de dados: 42
Autores: DOSREIS,GEORGE A.
Trypanosomatid protozoan parasites express an aggressive strategy of parasitism by infecting host macrophages and inducing extensive T-lymphocyte activation. One goal of such strategy is to drive the immune response of genetically susceptible hosts to a state of unresponsiveness regarding parasite killing. Unresponsiveness is achieved through different mechanisms, depending on the parasite species. In this brief review, recent findings on the molecular and cellular bases of the parasites' exploitation of host immune responses are discussed.
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Trypanosoma cruzi; Leishmania chagasi; T lymphocytes; CTLA-4; Apoptosis; Transforming growth factor.
Ano: 2000
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652000000100011

Citometria de fluxo no diagnóstico da leishmaniose visceral canina
Provedor de dados: 45
Autores: Carvalho Neta,A.V.; Rocha,R.D.R.; Gontijo,C.M.F.; Reis,A.B.; Martins-Filho,O.A.
Descreve-se a padronização de nova metodologia para detecção de anticorpos antiformas promastigotas fixadas de L. (L.) chagasi, por citometria de fluxo (AAPF-IgG), sua aplicabilidade e desempenho na identificação de casos de leishmaniose visceral canina (LVC). Foram avaliados dois grupos de cães classificados pela reação de imunofluorescência indireta (RIFI), como: não reatores (NR, n=10) e reatores (R, n=50) dos quais foram coletadas amostras de sangue (soro) para realização dos testes laboratoriais. Os resultados relacionados ao estabelecimento, aplicabilidade e desempenho da metodologia AAPF-IgG demonstraram que essa metodologia possibilita a identificação de uma região de reatividade diferencial entre cães NR e R, no soro diluído a 1:2048 e o valor de...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Leishmaniose visceral canina; Diagnóstico sorológico; Citometria de fluxo; Leishmania chagasi; Leishmania infantum.
Ano: 2006
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352006000400005

Leishmanicidal activity of carvacrol-rich essential oil from Lippia sidoides Cham
Provedor de dados: 48
Autores: Farias-Junior,Paulo A; Rios,Marcos C; Moura,Tauanny A; Almeida,Roque P; Alves,Pericles B; Blank,Arie F; Fernandes,Roberta P M; Scher,Ricardo.
Leishamaniasis is a disease that affects more than 2 million people worldwide, whose causative agent is Leishmania spp. The current therapy for leishmaniasis is far from satisfactory. All available drugs, including pentavalent antimony, require parenteral administration and are potentially toxic. Moreover, an increase in clinical resistance to these drugs has been reported. In this scenario, plant essential oils used traditionally in folk medicine are emerging as alternative sources for chemotherapeutic compounds. In this study, in vitro leishmanicidal effects of a thymol- and a carvacrol-rich essential oil from leaves of Lippia sidoides Cham. were investigated. The essential oils were extracted and their constituents were characterized by gas...
Tipo: Journal article
Palavras-chave: Carvacrol; P-cymene; Essential oil composition; Leishmania chagasi; Lippia ssp.; Thymol; Verbenaceae.
Ano: 2012
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000400012

Phenolic Composition and Leishmanicidal Activity of Red Propolis and Dalbergia ecastaphyllum (L.) Taub (Fabaceae) Extracts from Sergipe, Brazil
Provedor de dados: 52
Autores: Araujo,Jaltaira Montalvão Etinger; Mendonça-Melo,Lucyana Santos; Araujo,Edilson Divino; Fernandes,Roberta Pereira Miranda; Scher,Ricardo.
ABSTRACT Leishmaniasis is a parasitic disease caused by protozoa of the Leishmania genus. It may manifest in visceral and tegumentary forms, and pentavalent antimonials are the first choice drugs used for the treatment. Frequently these drugs show low efficiency and high toxicity to mammalian host. The present study describes the chemical profile and the in vitro leishmanicidal effects of red propolis and Dalbergia ecastaphyllum extracts from Sergipe, Brazil, in Leishmania chagasi and Leishmania amazonensis promastigotes. The phenolic composition of the extracts was evaluated by direct infusion electrospray ionization mass spectrometry (ESI-MS) fingerprinting. The leishmanicidal effect was evaluated by the Resazurin colorimetric method. Similar composition...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Brazilian red propolis; Chemical composition; Leishmania amazonensis; Leishmania chagasi.
Ano: 2018
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132018000100306