Consulta: subjectFacets:"Polycystic ovarian syndrome (PCOS)"
Registros recuperados: 1
Data/hora: 02/06/2024 05:35:06

Bee venom treatment reduced C-reactive protein and improved follicle quality in a rat model of estradiol valerate-induced polycystic ovarian syndrome
Provedor de dados: 80
Autores: Karimzadeh,L; Nabiuni,M; Sheikholeslami,A; Irian,S.
Polycystic ovarian syndrome (PCOS) is a low grade inflammatory disease characterized by hyperandrogenemia and chronic anovulation. C-reactive protein (CRP), released by adipocytes, plays a key role in PCOS. Apis mellifera honeybee venom (HBV) contains a variety of biologically active components with various pharmaceutical properties. This study was designed to assess the possibility of HBV application as an anti-inflammatory therapeutic agent. To induce PCOS, 1 mg/100 g body weight estradiol valerate (EV) was subcutaneously (SC) injected into eight-week-old rats. After 60 days, 0.5 mg/kg HBV was administered SC for 14 consecutive days, and the results of PCOS treatment were investigated. Rats were then anesthetized with chloroform, and their ovaries and...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Polycystic ovarian syndrome (PCOS); Honeybee venom (HBV); C-reactive protein (CRP); Estradiol valerate (EV); Corpus luteum; Chemiluminescence immunoassay.
Ano: 2012
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992012000400006