Consulta: subjectFacets:"Rabbits"
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Data/hora: 06/06/2024 02:37:17

Respuesta de conejos alimentados con veza fresca o un suplemento a base de maíz germinado o cebada germinada durante el periodo de engorda
Provedor de dados: 32
Autores: Avendaño Jiménez, Josefa Guadalupe.
Con la finalidad de encontrar una alternativa de alimentación de bajo costo en conejos de engorda, que pueda  ser utilizada en zonas rurales, se realizaron dos experimentos. En el primero, se evaluó la respuesta productiva de 204 gazapos destetados de 28 días de edad, a los cuales se les asigno al azar uno de cuatro tratamientos: T1: veza fresca y maíz germinado durante seis semanas de engorda (n = 51 conejos); T2: veza fresca y alimento comercial durante seis semanas de engorda (n = 51 conejos); T3: veza fresca y maíz germinado hasta la cuarta semana de engorda y a partir de la quinta y sexta semana veza fresca y alimento comercial (n = 51 conejos) y T4: alimento comercial durante seis semanas de engorda (n = 51 conejos). En el segundo  experimento, se...
Tipo: Tesis
Palavras-chave: Conejos; Veza fresca; Maíz germinado; Cebada germinada; Características productivas; Maestría; Ganadería; Rabbits; Fresh vetch; Sprouted corn; Sprouted barley; Productive performance.
Ano: 2009
URL: http://hdl.handle.net/10521/1392

Suplemento con germinados de trigo como bioestímulo reproductivo en conejos machos.
Provedor de dados: 32
Autores: Fallas López, Marianella.
Los germinados de trigo contienen un compuesto fenólico 6-methoxi-2-benzoxazolinone (6-MBOA) que estimula la reproducción en ciertas especies pequeñas de mamíferos herbívoros, pero esto no se ha demostrado en machos.  El objetivo del presente estudio fue evaluar el efecto de suplementar, por periodos cortos, con germinados de trigo en la libido y calidad del semen de conejos. Se colocaron machos Nueva Zelanda Blanco puberales de cinco meses de edad (n = 18) en dos grupos similares de acuerdo a sus pesos y asignados completamente al azar a uno de dos tratamientos experimentales: (1) Dieta peletizada comercial únicamente o testigo; (2) dieta peletizada comercial más germinados de trigo (300g animal-1 d-1). El diseño experimental fue completamente al azar con...
Palavras-chave: Conejos; 6-methoxi-2-benzoxazolinone; Orden de eyaculado; Estación; Semen; Rabbits; Number of ejaculation; Season; Semen; Maestría; Ganadería.
Ano: 2010
URL: http://hdl.handle.net/10521/289

Ultrastructural Study of Poxvirus Causing Myxomatosis in Rabbits, in São Paulo and Santa Catarina, Brazil
Provedor de dados: 77
Autores: Catroxo,M. H. B; Bersano,J. G; Martins,A. M. C. P. F; Petrella,S; Portugal,M. A. S. C; Souza,O. S.
The myxomatosis is a contagious worldwide disease caused by poxvirus which infects domestic and wild rabbits. In the present study we present two distinct outbreaks of myxomatosis when raising rabbits, one for commercial purpose of production of meat and skins and, another one for the commercialization of ornamental rabbits. The observed signs were ocular, auricular, nasal, testis lesions and many times scattered throughout the body of the animals. The lesions were characterized by formation of nodules that by palpation disclosed gummy or gelatinous aspect. At the transmission electron microscopy, all the skin and crust samples were analyzed by negative staining technique. A great number of particles with morphology similar to the poxvirus, some enveloped...
Tipo: Journal article
Palavras-chave: Myxomatosis; Poxvirus; Rabbits; Transmission electron microscopy.
Ano: 2009
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000200039

Application of Principal Component Factor Analysis in Quantifying Size and Morphological Indices of Domestic Rabbits
Provedor de dados: 77
Autores: Yakubu,A; Ayoade,J. A.
Body weight and four morphostructural traits namely body length, heart girth, thigh circumference and ear length of 103 New Zealand White x Chinchilla crossbred rabbits were measured. The investigation aimed at describing objectively the interdependence among conformation traits and to predict body weight from their independent factor scores using principal component analysis. Phenotypic correlations between body weight and body dimensions were highly significant (r=0.61 ­ 0.91; P&lt;0.01). Pairwise correlations of the body shape characters ranged from moderate to high values. From the factor analysis with varimax rotation of the intercorrelated traits, two principal components which accounted for 90.27% of the total variance were extracted. The first...
Tipo: Journal article
Palavras-chave: Body size; Growth; Rabbits.
Ano: 2009
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000400009

Patterns of Sudanophilic Lesions at Ostia of Descending Thoracic and Abdominal Aorta in Cholesterol-Fed Adult Rabbits
Provedor de dados: 77
Autores: Shahid,Uzma; Butt,Shadab Ahmed; Zareen,Nusrat.
Sudan-positive atherosclerotic lesions preferentially occur at downstream and lateral margins of arterial branch ostia in human neonates and weanling rabbits but tend to develop at lateral and upstream margins in old subjects. We investigated (i) the pattern of sudanophilic lesions at aortic ostia of cholesterol-fed adult rabbits and (ii) determined any differences in lesion distribution between descending thoracic and abdominal aorta. Ten adult males, New Zealand white rabbits were fed 2% high cholesterol diet. After six weeks, aortas were excised, opened longitudinally and stained with Sudan-IV for gross examination of atherosclerotic lesions. A total of 156 descending thoracic and 90 abdominal ostia were examined. Mean lesion frequencies upstream,...
Tipo: Journal article
Palavras-chave: Sudanophilic lesions; Aorta; Ostia; Rabbits.
Ano: 2011
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000300013

Histomorphology of Liver, Testicle and Body Fat in Farm Rabbits Fed with an Obesogenic Diet During the Peripuberal Period
Provedor de dados: 77
Autores: Mejía Huerta,Nancy Guadalupe; Córdova Izquierdo,Alejandro; Aragón Hernández,Jesús; Flores Pérez,Fernando Iván; Pérez-Martínez,Mario.
Two groups were formed in order to evaluate the effect of an obesogenic diet on body and liver weight, body fat accumulation and the histometric characteristics of liver and testicles of New Zealand rabbits during the peripuberal period. One group received a standard farm diet and the other received a standard farm diet with canola oil added. During the study, weight of both groups was recorded. At the end of the study, the rabbits were euthanized and liver, testicles, and visceral, scapular and scrotal fat were weighed. Tissue samples were obtained from liver and testicles to carry out histometric analysis. Body weight, body mass index, liver and visceral fat weight were significantly different (P&lt;0.01) in the obesogenic diet when compared to the...
Tipo: Journal article
Palavras-chave: Histometry; Rabbits; Liver; Testicle; Weight; Peripuberal period.
Ano: 2015
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000400030

Clinical and pathological characterization of Blood stream forms and cerebrospinal fluid T. b. rhodesiense trypanosomes isolated from a patient using rabbits
Provedor de dados: 19
Autores: Ndungu, K; Kagira, J.M; Ngotho, J.M; Ouma, J; Bett, B; Gitonga, P.
Clinical and pathological characterisation of blood stream (BSF) and cerebrospinal fluid (CSF) forms of Trypanosoma brucei rhodesiense trypanosome isolated from a sleeping sickness patient were investigated in rabbits. The study aimed at investigating whether there is any significant difference in clinical and pathological presentation in rabbits infected by the two forms of trypanosomes. Each form of parasite was inoculated into five rabbits at 104 trypanosomes/ml while five rabbits were used as un-infected controls. Parasitaemia development, body temperature, packed cell volume (PCV), body weight, food and water intake, heartbeat and respiration were monitored daily for 30 days post infection when the experiment was terminated. Pathological changes were...
Palavras-chave: Pathogenicity; Rabbits; T. b. rhodesiense; CSF and Blood stream forms.
Ano: 2009
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/2387

Pathogenesis of meningoencephalitis in rabbits by bovine herpesvirus type-5 (BHV-5)
Provedor de dados: 59
Autores: Silva,Adriana M. da; Flores,Eduardo F.; Weiblen,Rudi; Canto,Marister C.; Irigoyen,Luiz F.; Roehe,Paulo M.; Sousa,Renato S. de.
This article describes the main aspects of bovine herpesvirus type-5 (BHV-5) neurologic infection and disease in rabbits, a candidate animal model for studying BHV-5 neuropathogenesis. Intranasal inoculation of weanling rabbits with a Brazilian BHV-5 isolate produced neurological disease and death in 78.8% (26/33) of the animals. Neurological signs started as early as 5 days post-inoculation and lasted from 10-12 hours up to several days. Most animals evolved to a moribund state or death within 24 (69.2%) to 48 hours (88.5%). Neurological disease was characterized by excitability or depression, tremors, bruxism, walking or running in circles, backward arching of the head and body, incoordination, backward and sideways falling, paddling, profound depression...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Bovine herpesvirus type-5; BHV-5; Meningoencephalitis; Rabbits; Animal model.
Ano: 1999
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37141999000100005

Migration of Schistosoma mansoni sambon (Trematoda, Schistosomatidae) from skin to lungs in immunized NZ rabbits (Lagomorpha, Leporidae) by autoradiographic analysis
Provedor de dados: 104
Autores: Pinto,R. Magalhães; Noronha,Dely; Almeida,Marília S. S; Katz,Naftale; Tendler,Miriam.
Skin to lung migration of Schistosoma mansoni Sambon, 1907 - (75 Se) - selenomethionine-labeled cercariae was tracked by tissue autoradiography on days 1, 4, 6, 8 after challenge, in rabbits immunized with a S. mansoni derived saline extract. Either in vaccinated animals or in those of the control unprimed group, the peak of skin schistosomula occurs 24hs after infection. Comparison between peaks of lungs migrating larvae showed that, in control animals, the increase of worm burden in this site, is detected on the 6th day post-infection, differing from immunized rabbits, in which this peak occurs on day 4, when skin and lungs counts are still equivalent, decreasing gradually, showing a different pattern of the S. mansoni migration and suggesting that main...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Schistosoma mansoni; Migration; Autoradiography; Immunization; Rabbits.
Ano: 1994
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-81751994000400006

Avaliação do desempenho de coelhas alimentadas com farelo de canola em substituição parcial ou total ao farelo de soja
Provedor de dados: 2
Autores: Scapinello, Cláudio; UEM; Lage, Ligia Vieira; UEM; Prado, Ivanor Nunes do; UEM.
The effect of partial and total substitution of soybean meal crude protein (SBM) by canola meal (CM) on live weight (LW), daily weight gain (DWG), daily feed intake (DFI) and feed conversion (FC) in female rabbits are provided. Rabbits were evaluated from weaning period (43 days of age) to adult life when they are capable of reproduction (150 days of age). Forty-eight White New Zealand females were used and distributed in four treatments. SBM was substituted at 00%, 33%, 66% and 100% levels by CM. The partial or total substitution of SBM by CM did not change (P &gt; 0.05) the LW after 70 days old. Dunnett’s test showed that, independently of substitution level, FC of animals fed on meal with 33% SBM substitution by CM from age 43 to 90 days and 43 to 150...
Palavras-chave: 5.04.00.00-2 Zootecnia feed conversion; Feed intake; Rabbits; Reproduction 5.04.00.00-2 Zootecnia.
Ano: 2001
URL: http://periodicos.uem.br/ojs/index.php/ActaSciAnimSci/article/view/2661

Growth Performance of Male NZW Rabbits Fed Diets Supplemented with Beneficial Bacteria or Live Yeast
Provedor de dados: 111
Autores: El-Badawi, Alaa Yehia.
 Sixty male growing NZW rabbits aged eight weeks old, weighed in average 837.0±50.0g were randomly ranked in four equal groups to feed on four experimental diets for 10 weeks. All groups were fed a uniform rabbits pelleted diet, where R1 diet was without supplement ( control ), R2 supplemented with 0.1% Bacillus subtilis , R3 with 0.1% live Saccharomyces cerevisiae and R4 with 0.05% Bacillus s. + 0.05% Sacchromyces c. mixture. The results indicated that the voluntary feed intake did not influenced by bacteria or yeast supplementations, meanwhile body  weight gain and feed  efficiency  were obviously improved ( P &lt; 0.05 )  with  diets supplemented with yeast, bacteria or their mixture than control. Nutrients digestion coefficients and dietary nitrogen...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Rabbits; Probiotics; Carcass charactristics rabbits  growth performance  probiotics  carcass characteristics  body composition.
Ano: 2018
URL: http://www.cigrjournal.org/index.php/Ejounral/article/view/4519

Technique of spinal cord compression induced by inflation of epidural balloon catheter in rabbits (Oryctologus cuniculus): efficient and easy to use model
Provedor de dados: 42
Autores: FONSECA,ANTONIO F.B. DA; SCHEFFER,JUSSARA P.; COELHO,BARBARA P.; AIELLO,GRACIANE; GUIMARÃES,ARTHUR G.; GAMA,CARLOS R.B.; VESCOVINI,VICTOR; CABRAL,PAULA G.A.; OLIVEIRA,ANDRÉ L.A.
ABSTRACT The most common cause of spinal cord injury are high impact trauma, which often result in some motor impairment, sensory or autonomic a greater or lesser extent in the distal areas the level of trauma. In terms of survival and complications due to sequelae, veterinary patients have a poor prognosis unfavorable. Therefore justified the study of experimental models of spinal cord injury production that could provide more support to research potential treatments for spinal cord injuries in medicine and veterinary medicine. Preclinical studies of acute spinal cord injury require an experimental animal model easily reproducible. The most common experimental animal model is the rat, and several techniques for producing a spinal cord injury. The...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Experimental; Neuro-traumatology; Paraplegia; Rabbits.
Ano: 2016
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000401511

Scintigraphy in postoperative follow-up of osteosynthesis of the femur with a bridge plate associated with an intramedullary pin in rabbits
Provedor de dados: 45
Autores: Borges,N.F.; Serakides,R.; Santos,R.G.; Diniz,S.O.F.; Cardoso,V.N.; Ucros,N.S.; Torres,R.C.S.; Cardoso,S.V.; Rezende,C.M.F.
The objective of this work was to monitor the consolidation of the femur after osteosynthesis with a bridge plate associated with the intramedullary pin using scintigraphy. We used seven New Zealand breed male rabbits, at 4 months of age, with a mean weight of 3.5 kg. We performed a three-phase bone scintigraphy with technetium-labeled methylene diphosphonate (99mTc-MDP) before and after surgery, and 20, 50 and 90 days postoperatively. The activity index (AI) was calculated by dividing the average number of uptake counts in the region of the osteotomy by the average number of counts in the corresponding region in the contralateral limb. Radiography was performed before surgery, after surgery, and 15, 30, 45, 60 and 90 days postoperatively. We found a...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Scintigraphy; Rabbits; Bridge plate; Biological osteosynthesis.
Ano: 2013
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352013000400018

Platelet rich plasma associated with heterologous fresh and thawed chondrocytes on osteochondral lesions of rabbits
Provedor de dados: 45
Autores: Filgueiras,R.R.; Del Carlo,R.J.; Alves,N.P.; Viloria,M.I.V.; McManus,C.M.; Castro,M.B.; Filgueiras,F.P.F.; Monteiro,B.S.; Almeida,R.M.; Andrade,R.R.
Chondrocytes obtained from stifle joint of New Zealand White rabbits were cultivated. Half of cells were maintained in culture for later implantation and the others frozen during six months to evaluate viability. A circular osteochondral defect was created in the right stifle of other twenty seven rabbits. The control group (CG) received no treatment. The thawed (TH) and fresh (FH) heterologous groups received, respectively, an implant of cultivated thawed or fresh heterologous chondrocytes associated with platelet rich plasma (PRP). The CG group showed greatest pain and lameness compared to the other groups seven days after the implantation. Microscopically, at 45 and 90 days, the TH and FH groups showed filling with cartilaginous tissue containing...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Rabbits; Articular cartilage; Chondrocyte implantation; Platelet rich plasma; Type II collagen.
Ano: 2014
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352014000100024

Dimethyl sulfoxide effects on the febrile response to lipopolysaccharide injection in rabbits
Provedor de dados: 45
Autores: Souza,A.H.; Valadão,C.A.A.; Selegatto,M.A.; Almeida,R.M.; Macari,M.
The present study was designed to determine whether DMSO causes an inhibition on the development of fever in rabbits. The intravenous administration of LPS (1.5µg.kg-1 body weight) caused fever in both saline+LPS and DMSO+LPS group, but the onset and magnitude of the induced fever were significantly different. The saline+LPS group presented a prototypic biphasic fever whereas the DMSO+LPS group presented an attenuated febrile response, but it was not abolished. These results suggest that DMSO may provide a protective mechanism against pyrogen LPS, probably through the modulation of NF-kB mediated events, such as fever.
Tipo: Info:eu-repo/semantics/article
Palavras-chave: LPS; Fever; DMSO; Rabbits.
Ano: 2008
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352008000300016

Systemic absortion and adverse effects of topical ocular use of ketorolac tromethamine and sodium diclofenac in New Zealand rabbits for 90 days
Provedor de dados: 45
Autores: Pereira,F.Q.; Santos,B.; Carboni,T.; Bender,M.; Driemeier,D.; Cunha,A.C.B.; Biajoli,M.G.; Mello,F.B.; Silva,P.R.; Pigatto,J.A.T.; Mello,J.R.B.
ABSTRACT The effect of the systemic absorption of 0.1% diclofenac sodium (DS) eyedrop was compared to that of 0.5% ketorolac tromethamine (KT) in female New Zealand white rabbits treated on both eyes three times a day for 90 days. The rabbits were divided in three groups of six animals (n= 18): KT group, DS group, and control (Co) group, in which saline (0.9% NaCl) solution was instilled. Water and food consumption were measured daily, clinical examination was performed weekly, and blood samples were collected every 30 days for laboratory examination. The plasma was analyzed for the presence of KT and DS by solid-phase extraction (SPE) associated with mass spectrometry (MS). Systemic absorption of these drugs was confirmed by SPE-MS, allowing their...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Rabbits; Eyedrops; NSAID; Systemic absorption.
Ano: 2019
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000601865

Experimental acrylonitrile butadiene styrene and polyamide evisceration implant: a rabbit clinical and histopathology study
Provedor de dados: 45
Autores: Gomes Júnior,D.C.; Nassar,E.J.; Dórea Neto,F.A.; Lima,A.E.; Martins Filho,E.F.; Oriá,A.P.
ABSTRACT The purpose of this study was to evaluate acrylonitrile butadiene styrene (ABS) and polyamide implants in rabbits submitted to evisceration at the macroscopic and microstructure level and to assess clinical response and histopathological changes as well. For the experimental study implants of 12mm diameter were prepared by rapid prototyping, weighed and the outer and inner surfaces evaluated macroscopically and by electron microscopy. In addition, a compression test was performed and ultrastructural damage was then determined. After evisceration of the left eyeball, nine New Zealand rabbits received ABS implants and nine others received polyamide implants. The animals were assessed daily for 15 days after surgery and every seven days until the end...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Rabbits; Ocular prosthesis; Polymers.
Ano: 2016
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352016000501168

A new surgical technique to treat corneal perforations using amniotic membrane and surgical adhesive
Provedor de dados: 45
Autores: Pontes,K.C.S.; Borges,A.P.B.; Eleotério,R.B.; Frazão,A.C.N.; Machado,D.P.D.; Reis,E.C.C.; Sepúlveda,R.V.; Duarte,T.S.; Laus,J.L.
The objectives of this study were to compare surgical techniques and the effects of using n-butyl 2-cyanoacrylate and bovine amniotic membrane to repair perforated lesions in corneas. Penetrating keratoplasty was performed in sixty New Zealand White rabbits under general anesthesia. Group 1 (G1) was treated with n-butyl 2-cyanoacrylate, group 2 (G2) received a fragment of amniotic membrane through the anterior chamber and application of n-butyl 2-cyanoacrylate over the lesion, group 3 (G3) was treated with the same technique as G2 with the addition of an amniotic membrane bandage covering the cornea and sutured in the limbus region, and group 4 (G4) was treated with an amniotic membrane sutured to the lesion and an amniotic membrane bandage sutured in the...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Rabbits; Cornea; Cyanoacrylate; Glycerin; Ophthalmic surgery.
Ano: 2014
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352014000300655

Effects of experimental infections with larvae of Eustrongylides ignotus Jäegerskiold, 1909 and Contracaecum multipapillatum (Drasche, 1882) Baylis, 1920 in rabbits
Provedor de dados: 45
Autores: Barros,L.A.; Tortelly,R.; Pinto,R.M.; Gomes,D.C.
Rabbits were infected per os with 10 Eustrongylides ignotus L4 and with 50 Contracaecum multipapillatum L3 per rabbit, recovered from naturally infected freshwater fishes (Hoplias malabaricus) in order to evaluate the patogenicity of these two nematode species in mammalian host. Two rabbits (20%) infected with E. ignotus died before the fourth day post-inoculation (one after 51 and the other after 78 hours). Six rabbits (60%) were inappetent until the fifth day following experimental inoculation. No clinical signs in rabbits inoculated with C. multipapillatum were observed; nevertheless, eight (80%) animals were positive for this nematode species. Rabbits inoculated with E. ignotus, had gastric congestion with hematoma of the gastric wall in 60% of the...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Eustrongilydes ignotus; Contracaecum multipapillatum; Experimental infection; Rabbits; Pathology.
Ano: 2004
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352004000300007

Spirulina platensis effects on the levels of total cholesterol, HDL and triacylglycerols in rabbits fed with a hypercholesterolemic diet
Provedor de dados: 52
Autores: Colla,Luciane Maria; Muccillo-Baisch,Ana Luiza; Costa,Jorge Alberto Vieira.
In this work, hypercholesterolemia was induced in rabbits by feeding them a high cholesterol diet (CD, 350 mg/d) and the effects of supplementing this diet with 0.5 g/d Spirulina platensis was evaluated by measuring the levels of serum total-cholesterol (TC), triacylglycerols (TAG) and high-density lipoprotein (HDL-cholesterol) at the start of the experiment and after 30 d and 60 d. It was found that the levels of serum cholesterol decreased from 1,054±101 mg.dL-1 in the rabbits fed a CD without S. platensis to 516±163 mg.dL-1 to those fed with a high cholesterol diet supplemented with S. platensis (significant at p &lt;0.0001). The addition of Spirulina to the cholesterolemic diet did not cause significative decrease on the levels of triacylglycerols in...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Spirulina platensis; Cholesterol; Rabbits.
Ano: 2008
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000200022

Production of rabbit antibodies against purified Glucose oxidase
Provedor de dados: 52
Autores: Zia,Muhammad Anjum; Ain,Qurat-ul; Iftikhar,Tehreema; Abbas,Rao Zahid; Rahman,Khalil-ur.
Glucose oxidase is an active oxygen species generating enzyme produced from Aspergillus niger grown in submerged fermentation. Disintegration of the mycelium resulted in high glucose oxidase activity that was subjected to ammonium sulfate precipitation at 60-85% saturation rates that resulted to 6.14 U mg -1 specific activity. Purification of enzyme by anion exchange column (DEAE-Cellulose) resulted into 22.53 U mg-1 specific activity and 10.27 fold purification. This was applied to sephadex G-200 column for gel filtration chromatography. It was observed that enzyme achieved 59.37 U mg-1of specific activity with 27.08 fold purity and 64.36% recovery. Purified glucose oxidase was injected into rabbits through intravenous route, to raise the glucose oxidase...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Glucose oxidase; A. niger; Antibodies; Rabbits.
Ano: 2012
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132012000100008

Evaluation of Reference Genes for Quantitative PCR in Four Tissues from Rabbits with Hypercholesterolaemia
Provedor de dados: 52
Autores: Zhang,Zhen; Wen,Bin; Xu,Yuan; Jiang,En-ze; Liu,Jia-yu; Zhu,Ke-li; Ning,Fang-yong; Du,Zhi-Heng; Bai,Xiu-Juan.
Abstract Rabbit with hypercholesterolaemia is an important model for studying cholesterol metabolism disease. This study aimed to evaluate the expression stability of nine reference genes for quantitative PCR (qPCR) analysis in adrenal gland, liver, spleen, and kidney tissue from rabbits with hypercholesterolaemia. In total, 30 male Harbin Large White (HLW) rabbits were fed a normal feed (n = 15) or a high cholesterol feed (n = 15) for 8 weeks to induce hypercholesterolaemia. Nine reference genes were verified by qPCR using cDNA extracted from rabbit tissue samples. For qPCR analysis, reference genes were evaluated using the RefFinder and GeNorm algorithms. Overall, seven rabbits with hypercholesterolaemia were identified based on body weight and total...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Evaluation; Reference genes; QPCR; Rabbits; Hypercholesterolaemia.
Ano: 2019
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132019000100428

Dexamethasone-induced reactivation of bovine herpesvirus type 5 latent infection in experimentally infected rabbits results in a broader distribution of latent viral DNA in the brain
Provedor de dados: 56
Autores: Mayer,S.V.; de Quadros,V.L.; Vogel,F.S.F.; Winkelmann,E.R.; Arenhart,S.; Weiblen,R.; Flores,E.F.
Bovine herpesvirus type 5 (BHV-5) is a major agent of meningoencephalitis in cattle and establishes latent infections mainly in sensory nerve ganglia. The distribution of latent BHV-5 DNA in the brain of rabbits prior to and after virus reactivation was studied using a nested PCR. Fifteen rabbits inoculated intranasally with BHV-5 were euthanized 60 days post-inoculation (group A, N = 8) or submitted to dexamethasone treatment (2.6 mg kg-1 day-1, im, for 5 days) and euthanized 60 days later (group B, N = 7) for tissue examination. Two groups of BHV-1-infected rabbits (C, N = 3 and D, N = 3) submitted to each treatment were used as controls. Viral DNA of group A rabbits was consistently detected in trigeminal ganglia (8/8), frequently in cerebellum (5/8),...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Bovine herpesvirus type 5; BHV-5; BHV-1; Latent infection; Rabbits; Brain.
Ano: 2006
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000300004

Repeatability of the “flash-replenishment” method in contrast-enhanced ultrasound for the quantitative assessment of hepatic microvascular perfusion
Provedor de dados: 56
Autores: Xie,Fang; Wan,Wen-Bo; Fei,Xiang; Zhang,Ming-Bo; Zhang,Yan; Wang,Hong-Wei; Tang,Jie; Tang,Wen-Bo; Luo,Yu-Kun.
This study aimed to evaluate the feasibility and repeatability of the flash-replenishment method in contrast-enhanced ultrasound (CEUS) perfusion imaging and assess quantitatively microvascular perfusion in the liver. Twenty healthy New Zealand rabbits were submitted to CEUS perfusion imaging with continuous intravenous infusion. Using flash-replenishment kinetics, the dynamic process of depletion and refilling of microbubble contrast agent was recorded. The hepatic microvascular perfusion parameters were calculated, including region of interest, peak intensity (PI), area under the curve (AUC), and hepatic artery to vein transit time (HA-HVTT). A consistency test was performed for multiple measurements by the same operator and blind measurements by two...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Flash-replenishment; Contrast-enhanced ultrasound; Liver ischemia-reperfusion injury; Microvascular perfusion; Rabbits.
Ano: 2018
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000400603

Protective effect of policosanol on atherosclerotic lesions in rabbits with exogenous hypercholesterolemia
Provedor de dados: 56
Autores: Arruzazabala,M.L.; Noa,M.; Menéndez,R.; Más,R.; Carbajal,D.; Valdés,S.; Molina,V.
Policosanol is a mixture of higher aliphatic alcohols purified from sugar cane wax, with cholesterol-lowering effects demonstrable in experimental models and in patients with type II hypercholesterolemia. The protective effects of policosanol on atherosclerotic lesions experimentally induced by lipofundin in rabbits and rats and spontaneously developed in stumptail monkeys have been described. The present study was conducted to determine whether policosanol administered orally to rabbits with exogenous hypercholesterolemia also protects against the development of atherosclerotic lesions. Male New Zealand rabbits weighing 1.5 to 2 kg were randomly divided into three experimental groups which received 25 or 200 mg/kg policosanol (N = 7) orally for 60 days...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Policosanol; Atherosclerotic lesions; Exogenous hypercholesterolemia; Rabbits.
Ano: 2000
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000700015

The use of ozonized oil in the treatment of dermatophitosis caused by Microsporum canis in rabbits
Provedor de dados: 58
Autores: Daud,Fernanda Vasquez; Ueda,Suely Mitoi Ykko; Navarini,Alessandra; Mímica,Lycia Mara Jenné.
The ozone is effective against most microorganisms due to its high oxidant power. Low concentrations and short-term contact are sufficient to inactivate bacteria, mold, yeast, parasites, seaweeds, protozoa and fungi. Microsporum canis is an important agent of dermatophitosis in human and animal. The aim of the current study was to assess the efficacy of ozonized oil over Microsporum canis in rabbits. Eighteen male New Zealand white rabbits, weight ranging from 2 to 3.2 kg were depilated in the cranial dorso-lateral and right caudal, and cranial and left caudal regions. The regions were inoculated with Microsporum canis, excepting the right caudal region, and were denominated TM, O, OM and M, respectively. After seven days, the treatment of lesions in TM...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Fungi; Microsporum; Oils; Ozone; Rabbits.
Ano: 2011
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822011000100035

Sildenafil citrate on retrobulbar and retinal circulation of rabbits
Provedor de dados: 65
Autores: Amaral,Andréia Vitor Couto do; Silva,Germana Alegro da; Costa,Ana Paula Araújo; Coelho,Cássia Maria Molinaro; Renzo,Roberta; Laus,José Luiz.
The effects of sildenafil on retrobulbar and retinal circulation were studied in 18 adult male, albino, homozygous rabbits, of the New Zealand White breed, randomly divided into 3 groups of 6 animals, for drug treatment at a dose of 3.5mg kg-1 every 24 hours, for 7, 15 and 30 days. Nine animals used for control were treated with saline solution at 0.9%. It was evaluated intraocular pressure (IOP), mean arterial pressure (MAP), ocular perfusion pressure (PPO), B-mode ultrasonography and fluorescein angiography before and at the end of treatments. A slight decrease in results of IOP, MAP and PPO after treatment with sildenafil was evident, however, there was no statistical significance. It was observed significant increased diameter of the ophthalmic artery...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Rabbits; Sildenafil citrate; Retrobulbar circulation; Retinal circulation; Ultrasonography; Fluorescein angiography.
Ano: 2014
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782014000801431

Correlation between systolic function and presence of myofibroblasts in doxorubicin-induced cardiomyopathy
Provedor de dados: 65
Autores: Gava,Fábio Nelson; Silva,Sheila Nogueira Saraiva da; Rosa,Fernando Azadinho; Ortiz,Edna Mireya Gómez; Rodrigues,Bruno Cristian; Bandarra,Márcio de Barros; Vasconcelos,Rosemeri de Oliveira; Camacho,Aparecido Antonio.
ABSTRACT: Cardiotoxicity induced by doroxubicin generates systolic disfunction and myocardial remodeling with presence of myofibroblasts. These cells are thought to be attracted to the injured heart to avoid the development of congestive heart failure. The objective of this study was to evaluate the systolic dysfunction generated by doxorubicin through Doppler echocardiography, and its correlation with the presence of myofibroblasts in the myocardium. Twenty-five New Zealand White rabbits were divided into two groups (control, and treated with doxorubicin). The drug was administered for six weeks; Doppler echocardiography was performed before the first, and after the last administration of doxorubicin. Immuno detection of myofibroblasts was performed by...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Α-SMA; Doxorubicin; Doppler echocardiography; Rabbits.
Ano: 2016
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782016000901642

Morphometry of megakaryocytes in the liver of New Zealand White rabbits during intrauterine and postnatal development
Provedor de dados: 65
Autores: Pacheco,Maria Rita; Ferreira,Nilson; Melo,Válder Rodrigues; Baraldi-Artoni,Silvana Martinez; Orsi,Antonio Marcos; Machado,Márcia Rita Fernandes; Oliveira,Fabrício Singaretti de.
The hepatic megakaryocytic cells of New Zealand White rabbit in the intrauterine phase and in the immediate postnatal period were studied. Statistical analysis of the data concerning the cytoplasm and nucleus of those cells, i.e., area, perimeter, maximum diameter, minimum diameter, volume and shape factor, presented significant differences (p&lt;0.01) for F values concerning the life phases studied on15th, 22nd and 29th day of intrauterine life and 10th day of postnatal life, and for F values for animal within each phase. The Tukey’s test showed that most of the parameters studied in the cytoplasm and nucleus of these megakaryocytic cells presented the lowest values on the 15th day of intrauterine life and the highest on the 22nd day of the same phase.
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Liver; Megakaryocytes; Morphometry; Rabbits.
Ano: 2002
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782002000600015