Consulta: subjectFacets:"Spleen"
Registros recuperados: 14
Data/hora: 01/06/2024 01:06:11

Acute Effects of Sulphur Mustard Gas on the Number of Lymphocytes in the Rat's Spleen
Provedor de dados: 77
Autores: Mehrdad,Jahanshahi; Bahadoran,H; Asadi,M. H.
Sulphur mustard (SM), commonly known as mustard gas is an alkylating agent that causes serious blisters upon contact with human skin. SM is frequently used as a chemical warfare agent. There is some evidence for sulfur mustard-induced lymph system effects in humans. Between 2000-2001, 42 male albino Wistar rats were used. After accommodation with environment, we divided rats to control, sham and experimental groups (2.5 mg/kg, 5 mg/kg, 10 mg/kg, 20 mg/kg and 40 mg/kg). Then we injected sulphur mustard oil in rat's intraperitoneal space. Then their spleens were removed for histological verification. Our results showed that significant difference in lymphocytes number in experimental groups after 24 hours. The number of lymphocytes in 5, 10, 20 and 40 mg/kg...
Tipo: Journal article
Palavras-chave: Mustard gas; Lymphocytes; Spleen.
Ano: 2008
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022008000200031

A Study on the Variations of Size, Shape and External Features of the Spleen in South Indian Population
Provedor de dados: 77
Autores: Nayak B,Satheesha; Somayaji,S. N; Soumya,K. V.
The spleen is the largest lymphoid organ. It is wedge shaped and measures about 1 inch thick, 3 inches broad and 5 inches long. It presents characteristic notches on its superior margin and has a hilum on the visceral surface. The aim was to study the anomalies related to size, shape and external features of the spleen and discuss their clinical importance. As there are not many reports on variations in size shape and features of spleen in the South Indian population, we decided to do this study on cadaveric specimens. We observed 50 spleens fixed with 10% formalin. Among the 50 spleens observed, 25 spleens (50%) were normal and had all the features explained in the textbooks. 25 spleens (50%) did not have any notches on the superior margin, 2 spleens (4%)...
Tipo: Journal article
Palavras-chave: Spleen; Anomaly; Variation; Splenic notch; Anatomy.
Ano: 2011
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000300001

Morphometric Alterations Induced by the Toxicity of Variable Sizes of Silver Nanoparticles
Provedor de dados: 77
Autores: Almansour,Mansour; Jarrar,Qais; Battah,Abdelkader; Jarrar,Bashir.
Silver nanoprticles (SNPs) are invested in medical, industrial and environmental applications. Little if any, is known about the morphometric alterations induced by the toxicity of SNPs. The aim of the present work is to find out the effect of variable size of SNPs on different morphometric parameters. Adult healthy male mice (BAL/C) were subjected to (10 nm, 20 nm, 40 nm 60 nm and 100 nm) SNPs for 35 days. Silver NPs caused non-significant decline on the average weight, significant decline in food consumption, increase in water intake, unilateral blindness, tanning fur color and cholestasis together with a decrease in the relative ratio of the liver, kidney and spleen weight to body weight. Mice subjected to 10 nm and 20 nm were more affected than mice...
Tipo: Journal article
Palavras-chave: Silver nanoparticles; Morphology; Toxicology; Liver; Kidney; Spleen.
Ano: 2015
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000200022

The Spleen of a Specialy Adapted Mammal: The Little Hairy Armadillo Chaetophractus vellerosus, (Xenarthra, Dasypodidae). A Light and Electron Microscopic Study
Provedor de dados: 77
Autores: Galíndez,Elena Juana; Estecondo,Silvia; Casanave,Emma B.
The spleen is a multifunctional organ. Its microarchitecture reflects so well the phylogeny as the adaptation to niche in each animal group and inclusive in each species. Armadillos, as ancient and isolated mammals, show a mixture of ancestral and modern structures. In this work the microanatomy and cytology of the spleen of the little hairy armadillo Chaetophractus vellerosus was studied. The material was fixed and processed according to the typical methods for light and electron microscopy. Results show a cumulative medium sized spleen with the typical pulps. The white pulp is well developed but less defined than in other armadillos. The presence of follicular-dendritic-like cells and interdigitant dendritic-like cells, as well as clusters of...
Tipo: Journal article
Palavras-chave: Xenarthra; Dasypodidae; Spleen; Chaetophractus vellerosus.
Ano: 2006
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022006000400008

Distribution and Expression of Visfatin-Positive Cells in the Spleen of Lipopolysaccharide-Stimulated Piglets
Provedor de dados: 77
Autores: Xiao,Ke; Qiu,Chang-Wei; Chen,Min; Yang,Zhi; Wang,Jing; Peng,Ke-Mei; Song,Hui.
The histological changes in the spleen and the immunohistochemical expression of visfatin in lipopolysaccharide-stimulated piglets are reported to examine the relation between visfatin and inflammation. The results are as follows: (1) After LPS treated, the spleen displayed thicker capsules and trabecula, the thinner periarterial lymphatic sheath, and the more expandable splenic sinusoid, with an increase in the number of splenic nodules, lymphocytes, ellipsoids of the marginal zone, red blood cells and macrophagocytes. (2) Visfatin-positive cells were mainly distributed in the red pulp of the spleen, with less in splenic nodules and periarterial lymphatic sheath. In the LPS-treated group, the signal intensity and quantity of the visfatin-positive cells...
Tipo: Journal article
Palavras-chave: Visfatin; Spleen; Lipopolysaccharide; Piglets.
Ano: 2014
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000400052

Different Activation of Lymphocytes in Reaction to Babesia microti Infection in iNOS-/- and Wildtype Mice
Provedor de dados: 19
Autores: Remer, Katharina; Igarashi, Ikuo; Inoue, Noboru; Nagasawa, Hideyuki; Toyoda, Yutaka; Suzuki, Naoyoshi; 五十嵐, 郁男; 井上, 昇; 長澤, 秀行.
Palavras-chave: Lymphocytes; Babesia microti; Spleen; INOS-/- mice; CD4+ cells; CD8+ cells; IFN-γ; Antibody-titer.
Ano: 1997
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/263

CHARACTERIZATION OF CD11c+ DENDRITIC CELL POPULATIONS IN SPLEENS OF MICE INFECTED WITH TOXOPLASMA GONDII
Provedor de dados: 19
Autores: Makala, Levi H. C; Zayatiin, Batsukh; Kamada, Takenori; Seng, Seyha; Ribas, Lazaro; Mishima, Masayuki; Fujisaki, Kozo; Mikami, Takeshi; Suzuki, Naoyoshi; Nagasawa, Hideyuki.
Palavras-chave: Spleen; Dendritic cell; Mouse; Toxoplasma lysate antigen (TLA).
Ano: 2002
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/625

Effect of inoculation route on the production of antibodies and histological characteristics of the spleen in laying hens
Provedor de dados: 89
Autores: Eto,SF; Andrade,FG; Pinheiro,JW; Balarin,MR; Ramos,SP; Venancio,EJ.
Recent studies have reported the use of IgY antibody in the prevention or treatment of diseases in animals. IgY can be obtained in large amounts from the yolk of chicken eggs through a low-cost process. This study evaluated the effect of different routes of inoculation on antibody production and spleen morphological characteristics of laying hens (White Leghorn) inoculated with sheep red blood cells. The analysis of the results showed that the intramuscular route is the most efficient for total antibody production in the primary immune response, while the intravenous route is the most efficient in producing IgY antibodies in the secondary immune response. No histological changes were observed in the spleen of laying hens. This study could be useful for...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Antibody production; Humoral immunity; IgY; Laying; Spleen.
Ano: 2012
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2012000100011

Haematology and melanoma crophage centers of Nile tilapia fed supplemented diet with propolis
Provedor de dados: 3
Autores: Ledic-Neto, Jerko; Universidade Federal de Santa Catarina; Dotta, Geovana; Universidade Federal de Santa Catarina; Garcia, Patrícia; Universidade Federal de Santa Catarina; Brum, Aline; Universidade Federal de Santa Catarina; Gonçalves, Eduardo Luis Tavares; Universidade Federal de Santa Catarina; Martins, Maurício Laterça; Universidade Federal de Santa Catarina.
The objective of this study was to investigate the influence of dietary supplementation with propolis on hematology and number and area of melanomacrophage centers in spleen and kidney of tilapia. After acclimation, fish (24.7 ± 7.4 gmean weight) were distributed in 6 tanks 100 L, 6 fish per tank, in triplicate, at a temperature 24.0 ± 2.8oC, with two treatments: Fish fed 2% propolis supplemented diet and fish fed non-supplemented diet. To monitor the evolution of the effects, two samples were collected: half of the fish from each treatment were used after 15 days and the other half after 21, composing two feeding times. After each feeding time, blood, spleen and kidney were collected. After twenty one days feeding on 2% propolis supplemented diet, fish...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: 5.06.03.00-0 fish; Blood; Kidney; Spleen; Hemosiderin Aquicultura.
Ano: 2014
URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/22024

Horse spleen segmentation technique as large animal model of preclinical trials
Provedor de dados: 42
Autores: Foz Filho,Roberto P.P.; Martin,Benedito W. de; Lima,Ana Rita de; Miglino,Maria Angélica.
The parenchymal distribution of the splenic artery was studied in order to obtain anatomical basis for partial splenectomy. Thirty two spleens were studied, 26 spleens of healthy horses weighing 320 to 450kg, aged 3 to 12 years and 6 spleens of fetus removed from slaughterhouse. The spleens were submitted to arteriography and scintigraphy in order to have their vascular pattern examined and compared to the external aspect of the organ aiming establish anatomo-surgical segments. All radiographs were photographed with a digital camera and the digital images were submitted to a measuring system for comparative analysis of areas of dorsal and ventral anatomo-surgical segments. Anatomical investigations into the angioarchitecture of the equine spleen showed a...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Arteriography; Equine; Scintigraphy; Spleen; Splenic artery.
Ano: 2013
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652013000401411

Effects of filgrastim on granulopoietic cells of mice pretreated with methotrexate
Provedor de dados: 47
Autores: Barrios,Lilian; Poletti,Oscar Héctor.
We have evaluated the effect of filgrastim on proliferation and differentiation activity of granulopoietic cells in mice pretreated with methotrexate. Filgrastim was injected daily, from day 8 to 28 after cytotoxic agent administration. The granulopoiesis changes were measured by assessment of GM-CFU cells content, marrow and spleen granuloid cells pool as well as circulating neutrophils. In MTX pretreated mice, bone marrow GM-CFU oscillating values were higher than normal values, but these changes were not followed by high proliferative activity in granuloid precursor cell compartment. After MTX treatment, filgrastim administration was unable to stimulate marrow granulopoiesis as observed in normal mice. In the spleen, MTX led to dramatic changes in the...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Methotrexate; Filgrastim; Granulopoiesis; Bone marrow; Spleen.
Ano: 2005
URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452005000100002

Evaluation of possible failure of the mononuclear phagocyte system after total splenectomy in rats
Provedor de dados: 52
Autores: Marques,Ruy Garcia; Petroianu,Andy; Oliveira,Márcia Betânia Nunes de; Bernardo-Filho,Mário; Portela,Margareth Crisóstomo.
Young and adult Wistar rats were submitted to total splenectomy and compared to animals not submitted to any surgical manipulation in order to evaluate the phagocytic function of spleen. The animals were infected with Escherichia coli labeled with technetium-99m and killed 20 minutes later. Liver, lung, spleen and a blood clot sample were taken. No significant differences were found in the percentage of bacterial radioactivity uptake in mononuclear phagocyte system (MPS) organs in young and adult splenectomized rats. However, phagocytosis index by macrophages of MPS organs was smaller in splenectomized animals than in control group. Splenectomized rats were associated with a higher blood bacterial radioactivity uptake than animals of the control group...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Spleen; Splenectomy; Technetium-99m; Escherichia coli; Phagocytosis; Mononuclear phagocyte system.
Ano: 2004
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132004000200006

Case report: spontaneous rupture of the spleen due to dengue fever
Provedor de dados: 55
Autores: Miranda,L.E.C.; Miranda,S.J.C.; Rolland,M.
Spontaneous rupture of the spleen has been described in cases of hematologic, neoplasic and infectious diseases, or resulting from pancreatitis. We report a rare case of spontaneous splenic rupture, and favorable evolution after splenectomy, in a patient with dengue fever, which occurred during the last outbreak of dengue fever in Brazil.
Tipo: Info:eu-repo/semantics/report
Palavras-chave: Spleen; Rupture; Dengue fever.
Ano: 2003
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000600011

Impairment of the hematological response and interleukin-1β production in protein-energy malnourished mice after endotoxemia with lipopolysaccharide
Provedor de dados: 56
Autores: Fock,R.A.; Vinolo,M.A.R.; Blatt,S.L.; Borelli,P.
The objectives of this study were to determine if protein-energy malnutrition (PEM) could affect the hematologic response to lipopolysaccharide (LPS), the interleukin-1β (IL-1β) production, leukocyte migration, and blood leukocyte expression of CD11a/CD18. Two-month-old male Swiss mice were submitted to PEM (N = 30) with a low-protein diet (14 days) containing 4% protein, compared to 20% protein in the control group (N = 30). The total cellularity of blood, bone marrow, spleen, and bronchoalveolar lavage evaluated after the LPS stimulus indicated reduced number of total cells in all compartments studied and different kinetics of migration in malnourished animals. The in vitro migration assay showed reduced capacity of migration after the LPS stimulus in...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Blood; Bone marrow; Spleen; Interleukin-1β; Lipopolysaccharide; Malnutrition.
Ano: 2012
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012001200009