Consulta: subjectFacets:"Synergism"
Registros recuperados: 30
Data/hora: 06/06/2024 15:42:02

Mixtures between Beauveria bassiana and potassium silicate to manage thrips in tomato plants for industrial processing
Provedor de dados: 75
Autores: Pereira,Alexandre Igor A; Silva,Cide M da; Curvêlo,Carmen RS; Pontes,Nadson de C; Pereira,Jardel L; Tavares,Wagner de S; Zanuncio,José C; Luz,José Magno Q.
ABSTRACT Thysanoptera species can transmit virus to Solanaceae family vegetables, including tomato plants for industrial processing, causing the disease known as Tomato Spotted Wilt Virus (TSWV). Thrips resistance to insecticides indicate the urgent need of techniques adequate for Integrate Pest Management practices. The objective was to evaluate the control efficiency (CE%) against Frankliniella schultzei (Thysanoptera: Thripidae) of the fungus Beauveria bassiana (Bb), the resistance inducer potassium silicate (KSil) and the chemical insecticide profenophos + cypermethrin (PC) isolated, or in binary mixtures. The treatments were foliar spraying on tomato plants with Bb (T1), KSil (T2) and PC (T3) isolated or in mixtures of Bb+KSil (T4), PC+KSil (T5) and...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Frankliniella schultzei; Solanum lycopersicum; Entomopathogenic fungi; Silicon; Synergism; Tank mixture.
Ano: 2020
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-05362020000400415

Toxicite des Elements Metalliques Dissous pour les Larves d'Organismes Marins: Donnees Bibliographiques.
Provedor de dados: 5
Autores: Deslous-paoli, Jean-marc.
A bibliographic review has been made on the toxicity of ten metals for some marine larvae of commercial interest. We have classified, according to toxicity, organic salts of tin, mercury, silver, copper, zinc, nickel, lead, cadmium, chromium and manganese. Some synergistic effects of metals, temperature and salinity are described as well as the action of silt suspended in water.
Tipo: Text
Palavras-chave: Mollusca; Crustacea; Pollution effects; Bibliographies; Salinity; Temperature; Synergism; Heavy metals; Toxicity.
Ano: 1981
URL: http://archimer.ifremer.fr/doc/1981/publication-1885.pdf

Enhancement of domoic acid neurotoxicity on Diptera larvae bioassay by marine fungal metabolites
Provedor de dados: 5
Autores: Ruiz, Nicolas; Petit, Karina; Vansteelandt, Marieke; Kerzaon, Isabelle; Baudet, Joseph; Amzil, Zouher; Biard, Jean-francois; Grovel, Olivier; Pouchus, Yves Francois.
Peptaibols are small linear fungal peptides which are produced in the marine environment. They exhibit neurotoxicity by forming pores in neuronal membranes. This work describes their combine effect with domoic acid, a neurotoxic phycotoxin, on Diptera larvae. The Acute toxicity bioassay on this biological model was tested with a panel of different toxins (microbial, algal or fungal). It allowed the discrimination of neurotoxins and non-neurotoxic toxins, and an evaluation of the toxicity level (MED and ED50) which were correlated with published LD50 in mice for neurotoxins tested. The highest activities on this test were found for Na+ channel blockers tetrodotoxin (ED50 = 0.026 mg/kg) and saxitoxin (ED50 = 0.18 mg/kg). Domoic acid was less active with an...
Tipo: Text
Palavras-chave: Domoic acid; Peptaibol; Synergism; Neurotoxicity; Marine-derived fungal metabolite; Diptera larvae bioassay.
Ano: 2010
URL: http://archimer.ifremer.fr/doc/00002/11279/7886.pdf

Risky business: The combined effects of fishing and changes in primary productivity on fish communities
Provedor de dados: 5
Autores: Fu, Caihong; Travers-trolet, Morgane; Velez, Laure; Gruss, Arnaud; Bundy, Alida; Shannon, Lynne J.; Fulton, Elizabeth A.; Akoglu, Ekin; Houle, Jennifer E.; Coll, Marta; Verley, Philippe; Heymans, Johanna J.; John, Emma; Shin, Yunne-jai.
There is an increasing need to understand community-level or whole-ecosystem responses to multiple stressors since the impacts of multiple stressors on marine systems depend not only on species- level responses, but also on species interactions and ecosystem structure. In this study, we used a multi-model ecosystem simulation approach to explore the combined effects of fishing and primary productivity on different components of the food-web across a suite of ecosystems and a range of model types. Simulations were carried out under different levels of primary productivity and various fishing scenarios (targeting different trophic levels). Previous work exploring the effects of multiple stressors often assumed that the combined effects of stressors are...
Tipo: Text
Palavras-chave: Marine ecosystem; Fishing; Combined effect; Meta-analysis; Synergism; Multiple drivers.
Ano: 2018
URL: https://archimer.ifremer.fr/doc/00414/52542/53368.pdf

The Cumulative Effects of Fishing, Plankton Productivity, and Marine Mammal Consumption in a Marine Ecosystem
Provedor de dados: 5
Autores: Fu, Caihong; Xu, Yi; Guo, Chuanbo; Olsen, Norm; Grüss, Arnaud; Liu, Huizhu; Barrier, Nicolas; Verley, Philippe; Shin, Yunne-jai.
The marine ecosystem off British Columbia (BC), Canada, has experienced various changes in the last two decades, including reduced lipid-rich zooplankton biomass, increased marine mammals, and deteriorated commercial fisheries, particularly those targeting pelagic species such as Pacific Herring (Clupea pallasii). Understanding how stressors interactively and cumulatively affect commercially important fish species is key to moving toward ecosystem-based fisheries management. Because it is challenging to assess the cumulative effects of multiple stressors by using empirical data alone, a dynamic, individual-based spatially explicit ecosystem modeling platform such as Object-oriented Simulator of Marine Ecosystems (OSMOSE) represents a valuable tool to...
Tipo: Text
Palavras-chave: Cumulative effect; Ecosystem-based fisheries management; Ecological indicator; Ecosystem modeling; Synergism.
Ano: 2020
URL: https://archimer.ifremer.fr/doc/00654/76615/77768.pdf

Biological properties of medicinal plants: a review of their antimicrobial activity
Provedor de dados: 80
Autores: Silva,NCC; Fernandes Júnior,A.
Plants have been used for thousands of years to flavor and conserve food, to treat health disorders and to prevent diseases including epidemics. The knowledge of their healing properties has been transmitted over the centuries within and among human communities. Active compounds produced during secondary vegetal metabolism are usually responsible for the biological properties of some plant species used throughout the globe for various purposes, including treatment of infectious diseases. Currently, data on the antimicrobial activity of numerous plants, so far considered empirical, have been scientifically confirmed, concomitantly with the increasing number of reports on pathogenic microorganisms resistant to antimicrobials. Products derived from plants may...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Medicinal plants; Phytochemistry; Antimicrobial activity; Plant extracts; Essential oils; Synergism.
Ano: 2010
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992010000300006

Anti-coagulase-negative Staphylococcus activity of ethanolic extracts of propolis from two Brazilian regions and synergism with antimicrobial drugs by the E-test method
Provedor de dados: 80
Autores: Mantovani,R. P.; Rall,V. L. M.; Batalha,J. E. N.; Fernandes,A. A. H.; Fernandes Junior,A.
Propolis is a natural resinous substance collected by bees from vegetal sources and its therapeutic properties have been investigated. In this work, we evaluated the inhibitory activity of ethanolic extracts of propolis (EEP) from the Southeast and South of Brazil on coagulase-negative Staphylococcus (CNS) growth as well as the EEP in vitro synergism with antimicrobial drugs by using the diffusion method (E-test). The EEP chemical characteristics (dry weight, pH, flavonoid and phenolic compounds) were determined. Seven drugs were tested, and synergism was observed between three drugs and Southeast EEP, six drugs and South EEP, and one drug and ethanol control. Ethanolic extracts of propolis from the South of Brazil presented the greatest flavonoid content...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Brazilian propolis; Coagulase-negative Staphylococcus; E-test; Antimicrobial drugs; Synergism.
Ano: 2008
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992008000200012

Evolution of social science research at ICRISAT, and a case study in Zimbabwe
Provedor de dados: 30
Autores: J.D.
Palavras-chave: Social sciences; Crop management; Cash flow; Assets; Synergism; Farm inputs; Agricultural credit; Strategies; Policies; Weather hazards.
Ano: 2005
URL: http://agropedia.iitk.ac.in/openaccess/?q=node/3321

Forging Research and Development Partnerships with Private Sector at ICRISAT-Sorghum as a Case Study
Provedor de dados: 30
Autores: Reddy, B.V.S.,( Belum V. S. Reddy ).
Palavras-chave: Hybrids; Sorghum; Seed production; Alcohols; Private sector; Synergism; Confectionery; Breeds (animals); Sampling; Millets.
Ano: 2005
URL: http://agropedia.iitk.ac.in/openaccess/?q=node/3247

Commelina Species Control with Desiccants Alone and in Mixtures
Provedor de dados: 87
Autores: FERREIRA,S.D.; SALVALAGGIO,A.C.; MORATELLI,G.; VASCONCELOS,E.D.; COSTA,N.V.
ABSTRACT: The objective of this study was to evaluate the chemical control of the species C. benghalensis and C. erecta with desiccants alone and mixtures, as well as the spreading of spray droplets on the leaf surfaces. The experimental design was completely randomized in a 2 x 16 factorial arrangement with four replications, totaling 32 treatments and 128 plots. The first factor is related to the species C. benghalensis and C. erecta and the second factor corresponds to the treatments carfentrazone-ethyl in doses of 15, 30, 60 g ha-1, which added 0.5% v v-1 adhesive spreader; glufosinate ammonium at doses of 100, 200, 400 g ha-1, added 0.5% v v-1 mineral oil; glyphosate at 240, 480, 960 g ha-1; carfentrazone-ethyl + glufosinate ammonium in doses of 100,...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Weed; Droplets surface tension; Spreader and sticker agent; Chemical control; Synergism.
Ano: 2017
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-83582017000100278

Herbicide Mixtures to Control Dayflowers and Drift Effect on Coffee Cultures
Provedor de dados: 87
Autores: FREITAS,N.M.; FREITAS,F.C.L.; FURTADO,I.F.; TEIXEIRA,M.F.F.; SILVA,V.F.
ABSTRACT: The dayflower species Commelina benghalensis and C. diffusa are among the main weeds in coffee crops. The purpose of this study was to evaluate the efficacy of herbicides/herbicide mixtures in controlling dayflower species and to evaluate the possible intoxication of coffee cultures, as well as the effect of mixture interactions. Two experiments were conducted, the first one in a 12 x 2 factorial arrangement with 12 herbicides/mixtures (glyphosate, glyphosate + metsulfuron-methyl, glyphosate + flumioxazin, glyphosate + 2.4-D, glyphosate + oxyfluorfen, glyphosate + carfentrazone-ethyl, metsulfuron-methyl, flumioxazin, 2.4-D, oxyfluorfen and carfentrazone-ethyl) and two dayflower species (C. benghalensis and C. diffusa) and the second one, in a 6 x...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Antagonism; Coffea arabica; Commelina benghalensis; Commelina diffusa; Synergism.
Ano: 2018
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-83582018000100248

Interaction Between Saflufenacil and Other Oxidative Stress Promoting Herbicides to Control Wild Poinsettia
Provedor de dados: 87
Autores: DIESEL,F.; VIECELLI,M.; TREZZI,M.M.; PAGNONCELLI JR.,F.B.
ABSTRACT: Synergism is a desired result in the interaction between herbicides because it provides many benefits, among which the reduction of doses and the increment of control efficiency, and because it positively signals for the joint application of herbicides. The objective of this study is to evaluate the effect of the association of saflufenacil with other herbicides that promote oxidative stress on the development of Euphorbia heterophylla as well as to analyze if the resulting interactions are antagonistic, additive or synergistic. The experiment was conducted in pots, in a greenhouse, using a completely randomized design with four replications. Treatments consisted of saflufenacil (0, 1,2, 2,32, 4,47, 8,63, 16,65 g ha-1) alone and associated with...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Euphorbia heterophylla; Synergism; Clomazone; Metribuzin; Paraquat.
Ano: 2018
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-83582018000100298

Response of Wheat Plants to Combinations of Herbicides with Insecticides and Fungicides
Provedor de dados: 87
Autores: VIECELLI,M.; PAGNONCELLI JR.,F.B.; TREZZI,M.M.; CAVALHEIRO,B.M.; GOBETTI,R.C.R.
ABSTRACT: The combination of herbicides and other pesticides can influence weed and crop management. This study aimed to evaluate the response of the combination of different herbicides with insecticides or fungicides of different chemical groups on the development and yield of wheat grains of the cultivar ORS Vintecinco. The experimental design was a randomized block design with three replications. The experiment consisted of 33 treatments, as follows: control without application and application of the herbicides 2,4-D (1,005 g a.e. ha-1), bentazon (756 g a.i. ha-1), metsulfuron-methyl (3 g a.i. ha-1), and pyroxsulam (16 g a.i. ha-1), isolated or combined with the insecticides chlorfluazuron (15 g a.i. ha-1), chlorpyrifos (720 g a.i. ha-1), deltamethrin...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Triticum aestivum; Synergism; Antagonism; Tolerance; Grain yield.
Ano: 2019
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-83582019000100263

ANTAGONISM IS THE PREDOMINANT EFFECT OF HERBICIDE MIXTURES USED FOR IMIDAZOLINONE-RESISTANT BARNYARDGRASS (Echinochloa crus-galli) CONTROL
Provedor de dados: 87
Autores: MATZENBACHER,F. O.; KALSING,A.; DALAZEN,G.; MARKUS,C.; MEROTTO JR,A.
ABSTRACTHerbicides mixtures are used in many situations without the adequate knowledge related with the effect on major target weeds. The objective of this study was to evaluate the effects of different herbicides mixtures used in irrigated rice in order to establish the adequate combinations for the prevention and management of herbicide resistance in barnyardgrass (Echinochloa crus-galli). Three experiments were performed at field conditions with all major post-emergent herbicides used in irrigated rice in Brazil. The first experiment was performed with barnyardgrass resistant to imidazolinone herbicides and herbicides applied at label rates. The second and third experiments were performed with barnyardgrass resistant and susceptible to imidazolinone...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: ALS inhibitors; Irrigated rice; Interaction; Synergism.
Ano: 2015
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-83582015000300587

Status and preliminary mechanism of resistance to insecticides in a field strain of housefly (Musca domestica, L)
Provedor de dados: 92
Autores: Li,Qingfeng; Huang,Jianbo; Yuan,Jianzhong.
ABSTRACT Resistance profiles of houseflies (Gol-RR) collected from a field in Golmud city, Qinghai province, China, were determined for seven insecticides using topical bioassays. Resistance ratios of &gt;1219.51, 153.17, &gt;35.43, 6.12, 3.24, 1.73, and 0.86-fold were obtained for propoxur, cypermethrin, imidacloprid, indoxacarb, chlorpyrifos, fipronil, and chlorfenapyr, respectively, relative to a laboratory susceptible strain (SS). Synergism experiments showed that piperonyl butoxide (PBO), triphenylphosphate (TPP), and diethyl maleate (DEM) increased propoxur toxicity by &gt;105.71, &gt;7.88, and &gt;5.15-fold in the Gol-RR strain, compared with 5.25, 2.00, and 1.39-fold in the SS strain, indicating the involvement of P450 monooxygenases, esterases,...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Acetylcholinesterase activity; Insecticide resistance; Musca domestica; Resistance mechanism; Synergism.
Ano: 2018
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0085-56262018000400311

Hierarchical establishment of information sources during foraging decision-making process involving Acromyrmex subterraneus (Forel, 1893) (Hymenoptera, Formicidae)
Provedor de dados: 92
Autores: Almeida,Nilhian Gonçalves De; Camargo,Roberto Da Silva; Forti,Luis Carlos; Lopes,Juliane Floriano Santos.
ABSTRACT During foraging, worker ants are known for making use of many information sources to guide themselves in external environments, especially individual (memory) and social (trail pheromone) information. Both kinds of information act in a synergic way, keeping the foraging process efficient and organized. However, when social and individual information is conflicting face a trail bifurcation, it is necessary to establish a hierarchical order so prioritizing one of them. This study aims to verify which information (social or individual) is prioritized by Acromyrmex subterraneus workers when facing a bifurcation in a Y-trail system. Only one branch of the Y-trail leads to food resource and it had a section covered by filter paper where trail pheromone...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Leafcutter ants; Trail pheromone; Memory; Synergism.
Ano: 2018
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0085-56262018000100036

Effects of single and double infections with Potato virus X and Tobacco mosaic virus on disease development, plant growth, and virus accumulation in tomato
Provedor de dados: 102
Autores: BALOGUN,OLUSEGUN S.; XU,LEIXIN; TERAOKA,TOHRU; HOSOKAWA,DAIJIRO.
The tomato cv. Fukuju nº. 2 was used for studying the effect of single and double infections with Potato virus X (PVX) and Tobacco mosaic virus (TMV). Mixed infection resulted in a synergistic increase of disease severity, where more growth reduction was seen with simultaneous inoculations than with sequential inoculations at four-day intervals. At five and 12 days post-inoculation, the increased severity of the disease coincided with enhancement of virus accumulation in the rapidly expanding upper leaves. The PVX concentration in leaves nº 5 to 7 of doubly infected plants was three to six fold that of singly infected ones, as determined by DAS-ELISA. Mixed infection with the L strain led to higher enhancement of PVX than with the TMV-L11A strain. The...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Synergism; Western blot; Northern hybridization; DAS-ELISA; Virus enhancement.
Ano: 2002
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-41582002000300001

Requirements of mixed tangerine (Citrus tangerine) and pineapple (Ananas comosus) powdered peel wastes fermentation for citric acid production
Provedor de dados: 111
Autores: Kumar, Prasanna GV; Paul, Sanjib Kumar; Khobragade, Chetan B; Bania, Bhargav Kumar; Sengupta, Debopriyo Kumar.
In this study, mixed substrate submerged fermentation of fruit peel wastes for the production of citric acid is reported. Powders of the peel wastes of tangerine and pineapple were used as substrates. Methanol (1-3% w/w) and sucrose (5-15% w/w) were supplemented in the fermentation media (pH on the range of 2.0-6.0) with moisture content of 90% (wet basis). Effect of substrate mix, pH of the media, methanol and sucrose concentrations on the yield of citric acid was studied, and their optimal levels for the maximum yield of citric acid were identified based on Taguchi method.  Methanol as stimulant in the medium and ratio of substrates in the mix had the highest influence on the yield of citric acid.  Fermentation media with tangerine and pineapple peel...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Chromatography; Kinetics; Mixed substrate fermentation; Optimization; Synergism; Taguchi method.
Ano: 2020
URL: http://www.cigrjournal.org/index.php/Ejounral/article/view/5487

Synergism of flavonoids with bacteriostatic action gainst Staphylococcus aureus ATCC 25 923 and Escherichia coli ATCC 25 922
Provedor de dados: 47
Autores: Alvarez,María De Los A.; Debattista,Nora B.; Pappano,Nora B.
In our previous studies, bacteriostatic action of flavonoids against Staphylococcus aureus ATCC 25 923 and Escherichia coli ATCC 25 922 was demostrated. In the present work synergism of their combinations in order to improve the bacteriostatic action against the same microorganisms was determined. The experiences were made in nutritive broth, maintaining constant one drug concentration (20 µg/ml) and increasing the other one. A turbidimetric kinetic method was used and by means of a mechanism previously proposed, the minimal inhibitory concentrations (MIC´s) of each flavonoid combination were determined. The MIC´s for assayed combinations against S. aureus were: variable morin - constant rutin: 157.44 µg/ml and variable quercetin - constant morin: 29.9...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Synergism; Flavonoids; Bacteriostatics; MIC.
Ano: 2006
URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452006000100006

Synergistic interaction of Helichrysum pedunculatum leaf extracts with antibiotics against wound infection associated bacteria
Provedor de dados: 48
Autores: AIYEGORO,OLAYINKA A; AFOLAYAN,ANTHONY J; OKOH,ANTHONY I.
The effect of combinations of the crude methanolic extract of the leaves of Helichrysum pedunculatum and eight first-line antibiotics were investigated by time kill assays against a panel of bacterial strains that have been implicated in wound infections. The plant extract showed appreciable antibacterial activities against the test bacteria with zones of inhibition ranging between 18 and 27 mm, and minimum inhibitory concentrations (MICs) varying between 0.1 and 5.0 mg/ml. The MICs of the test antibiotics range between 0.001 and 0.412 mg/ml, and combination of the plant extract and the antibiotics resulted in reduction of bacterial counts by between 0 and 6.63 Log10 cfu/ml. At V2 MIC, 56.81% synergy; 43.19% indifference and no antagonism were observed,...
Tipo: Journal article
Palavras-chave: Helichrysum pedunculatum; Time kill assay; Synergism.
Ano: 2009
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602009000300007

Antifungal activities of tacrolimus in combination with antifungal agents against fluconazole-susceptible and fluconazole-resistant Trichosporon asahii isolates
Provedor de dados: 55
Autores: Kubiça,Thaís Felli; Denardi,Laura Bedin; Azevedo,Maria Isabel; Oliveira,Vanessa; Severo,Luiz Carlos; Santurio,Janio Morais; Alves,Sydney Hartz.
ABSTRACT The antifungal activity of tacrolimus in combination with antifungal agents against different fungal species has been previously reported. Here we report the in vitro interactions between tacrolimus and amphotericin B, fluconazole, itraconazole, and caspofungin against 30 clinical isolates of both fluconazole-susceptible and fluconazole-resistant Trichosporon asahii. For these analyses, we used the broth microdilution method based on the M27-A3 technique and checkerboard microdilution method. Tacrolimus showed no activity against T. asahii strains (minimal inhibitory concentrations, MICs &gt; 64.0 µg mL−1). However, a larger synergistic interaction was observed by the combinations tacrolimus + amphotericin B (96.67%) and tacrolimus + caspofungin...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Susceptibility; FK506; Resistance; Synergism.
Ano: 2016
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000600539

Synergistic antitumor effect of TRAIL and adriamycin on the human breast cancer cell line MCF-7
Provedor de dados: 56
Autores: Cui,D.D.; Huang,Y.; Mao,S.H.; Chen,S.C.; Qiu,M.; Ji,L.L.; Yi,C.
The aim of the present study was to determine the effect of the combination of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and adriamycin (ADM) on the human breast cancer cell line MCF-7 and to identify potential mechanisms of apoptosis. Cell viability was analyzed by the MTT assay and the synergistic effect was assessed by the Webb coefficient. Apoptosis was quantified using the annexin V-FITC and propidium iodide staining flow cytometry. The mRNA expression of TRAIL receptors was measured by RT-PCR. Changes in the quantities of Bax and caspase-9 proteins were determined by Western blot. MCF-7 cells were relatively resistant to TRAIL (IC50 &gt;10 µg/mL), while MCF-7 cells were sensitive to ADM (IC50 &lt;10 µg/mL). A subtoxic...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: TRAIL; TRAIL receptors; Breast cancer; Adriamycin; Apoptosis; Synergism.
Ano: 2009
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000900013

Dipyridamole increases the cytotoxicity of cisplatin in human larynx cancer cells in vitro
Provedor de dados: 56
Autores: Rodrigues,M.; Barbosa Junior,F.; Perussi,J.R.
This paper describes the effect of dipyridamole (DIP) on the cytotoxicity of cisplatin in HEp-2 human larynx cancer cells in vitro and the nature of the interaction between cisplatin and dipyridamole. Cytotoxic assays were performed to obtain the IC50 for cisplatin. The cells were treated with 0, 20, 40, 80, 120 or 200 µM cisplatin, with or without a single concentration of DIP and incubated for 60 min at 37ºC and 5% CO2 for 3 days and then counted with a hemocytometer. The accumulation of cisplatin in the cells was measured by atomic absorption and fluorescence was used to determine the membrane binding constant of DIP. In the presence of 10, 20 and 30 µM DIP, the IC50 of cisplatin was reduced by 25, 60 and 82% in HEp-2 cells. Combination index analysis...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Cisplatin; Dipyridamole; Synergism; Tumor cells; Cytotoxicity; IC50.
Ano: 2004
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000400017

In vitro synergistic activity of antibiotic combinations against Brucella melitensis using E-test methodology
Provedor de dados: 58
Autores: Kilic,Selcuk; Dizbay,Murat; Hizel,Kenan; Arman,Dilek.
The treatment of brucellosis is still problematic, because of high rates of treatment failure or relapses. As the microorganism is an intracellular pathogen, treatment requires combined regimens. However, limited existing data on in vitro combinations are avaliable for Brucellae. The aim of this study was to investigate the in vitro efficacy of various traditional and new antibiotic combinations against 16 Brucella melitensis strains. The combination effect of antimicrobial agents was evaluated by E-test synergy method to obtain a fractional inhibitory concentration (FIC) index. Co-Trimoxazole (SXT) and moxifloxocin (MXF) exhibited the lowest MIC, while Rifampin (RIF) had the highest MIC in the study. Combinations with RIF showed the best synergistic...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Brucella melitensis; Antibiotics; Synergism.
Ano: 2008
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822008000200006

Antimycobacterial activity of the antiinflammatory agent diclofenac sodium, and its synergism with streptomycin
Provedor de dados: 58
Autores: Dutta,Noton K.; Dastidar,Sujata G.; Kumar,Asok; Mazumdar,Kaushiki; Ray,Raja; Chakrabarty,Atindra N.
Diclofenac sodium, an antiinflammatory agent, exhibited remarkable inhibitory action against both drug sensitive and drug resistant clinical isolates of Mycobacterium tuberculosis, as well as other mycobacteria. This drug was tested in vitro against 45 different strains of mycobacteria, most of which were inhibited by the drug at 10-25 µg/ml concentration. When tested in vivo, diclofenac, injected at 10 µg/g body weight of a Swiss strain of white mice, could significantly protect them when challenged with 50 median lethal dose of M. tuberculosis H37 Rv 102. According to chi2 test, the in vivo data were highly significant (p&lt;0.01). Diclofenac was further tested for synergism with the conventional antimycobacterial drug streptomycin against M. smegmatis...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Antiinflammatory drug; Diclofenac sodium; Antimycobacterial activity; Streptomycin; Synergism; Non-antibiotic.
Ano: 2004
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822004000300009

Bactericidal antibiotic-phytochemical combinations against methicillin resistant Staphylococcus aureus
Provedor de dados: 58
Autores: Kyaw,Bhone Myint; arora,Shuchi; Lim,Chu Sing.
Methicillin resistant Staphylococcus aureus (MRSA) infection is a global concern nowadays. Due to its multi-drug resistant nature, treatment with conventional antibiotics does not assure desired clinical outcomes. Therefore, there is a need to find new compounds and/or alternative methods to get arsenal against the pathogen. Combination therapies using conventional antibiotics and phytochemicals fulfill both requirements. In this study, the efficacy of different phytochemicals in combination with selected antibiotics was tested against 12 strains of S. aureus (ATCC MRSA 43300, ATCC methicillin sensitive S. aureus or MSSA 29213 and 10 MRSA clinical strains collected from National University Hospital, Singapore). Out of the six phytochemicals used, tannic...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Phytochemicals; Antibiotic combinations; Synergism; Antibiotic resistance; Methicillin-resistance Staphylococcus aureus (MRSA).
Ano: 2012
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822012000300013

Synergistic effect of ibuprofen with itraconazole and fluconazole against Cryptococcus neoformans
Provedor de dados: 60
Autores: Rocha,Letícia Fernandes da; Pippi,Bruna; Fuentefria,Alexandre Meneghello; Mezzari,Adelina.
The present study investigated the association of the non-steroidal anti-inflammatory drug ibuprofen with itraconazole, fluconazole and amphotericin B against Cryptococcus neoformans isolates. The minimal inhibitory concentration (MIC) was found according to M27-A3 protocol and in vitro interactions were evaluated using checkerboard microdilution method. Synergism was demonstrated between azoles and ibuprofen for most isolates. However, no synergistic effects were seen when amphotericin B was combined with ibuprofen. Therefore, our results suggest that ibuprofen presents clinical potential when combined with azole drugs in the treatment of cryptococcosis.
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Cryptococcus neoformans; Ibuprofen; Itraconazole; Fluconazole; Synergism.
Ano: 2020
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100577

Synergistic response of auxin and ethylene on physiology of Jatropha curcas L.
Provedor de dados: 61
Autores: Joshi,Gargi; Shukla,Arvind; Shukla,Alok.
Jatropha curcas L. is a versatile crop since all its plant material is brought to use either as energy source, industrial or medicinal purpose. Several studies are ongoing in different parts of the world to optimize, enhance and exploit the growth, fruiting cycle and different developmental stages of the plant so that the economic yield of the plants can be utilized to the fullest limits. Foliar application of plant growth regulators such as ethrel (an ethylene releasing compound), indole acetic acid (IAA) and naphthalene acetic acid (NAA) at 50, 100 and 150 ppm, was found to influence different morpho-physiological characters in Jatropha curcas L, such as plant height, collar diameter, tree spread, flower initiation, number of inflorescence per plant,...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Jatropha curcas; Auxin; Ethrel; Synergism; Morpho-physiological.
Ano: 2011
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-04202011000100009

Combined effects of garlic essential oil and allyl isothiocyanate against Escherichia coli O157:H7 in vitro and in pork sausage
Provedor de dados: 65
Autores: Bortolotto,Fernanda Cristina Kandalski; Ceccoti,Stephane Pini Costa; Orso,Paloma Bianca; Wolupeck,Hanna Lethycia; Holley,Richard Alan; Luciano,Fernando Bittencourt; Macedo,Renata Ernlund Freitas de.
ABSTRACT:  Escherichia coli O157:H7 is a toxigenic serotype of E. coli and has been associated with foodborne outbreaks involving meat products, vegetables and fresh produces worldwide. Salts for curing are usually employed as antimicrobials in the production of pork sausages. However, salts do not have a significant inhibitory effect on enterobacteria. Due to the growing demand for natural foods, the use of essential oils has been proposed as natural antimicrobials in food. This study aimed to evaluate the effects of garlic essential oil (GO) and allyl isothiocyanate (AITC) against E. coli O157:H7 in vitro and in pork sausage. The Minimal Inhibitory Concentration (MIC) and Minimal Bactericidal Concentration (MBC) of these oils, alone and in combination,...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Foodborne pathogens; Meat products; Natural preservatives; Synergism.
Ano: 2018
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782018001000750

Chemical composition and fumigant effect of essentialoil of Lippia sidoides Cham. and monoterpenes against Tenebrio molitor (L.) (coleoptera: tenebrionidae)
Provedor de dados: 64
Autores: Lima,Rafaela Karin; Cardoso,Maria das Graças; Moraes,Jair Campos; Carvalho,Stephan Malfitano; Rodrigues,Vanessa Gregório; Guimarães,Luiz Gustavo Lima.
The chemical composition of Lippia sidoides essential oils obtained by hydrodistillation was characterized and quantified by GC/MS and their insecticidal activity by fumigation test was assayed against Tenebrio molitor. Moreover, the toxicity of monoterpenes carvacrol, 1,8-cineol and thymol were also evaluated when applied alone or in binary (1:1) or tertiary (1:1:1) mixture. The essential oil of L. sidoides has as major constituents carvacrol (31.68%), ρ-cymene (19.58%), 1,8-cineole (9.26%) and ϒ-terpinene (9.21%), from a 21 compounds identified, being 92.53% of total. Both compounds have insecticidal activity against T. molitor, being the degree of toxicity of carvacrol &gt; 1,8-cineole &gt; L. sidoides essential oil &gt; thymol, and its respectively...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: "Alecrim pepper"; Mealworm; Natural compound; Toxicity; Synergism.
Ano: 2011
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-70542011000400004