Consulta: subjectFacets:"Tributyltin"
Registros recuperados: 7
Data/hora: 01/06/2024 09:56:21

Mutagenic effects of tributyltin and inorganic lead (Pb II) on the fish H. malabaricus as evaluated using the comet assay and the piscine micronucleus and chromosome aberration tests
Provedor de dados: 74
Autores: Ferraro,Marcos Vinícius M.; Fenocchio,Alberto Sérgio; Mantovani,Mario Sérgio; Ribeiro,Ciro de Oliveira; Cestari,Marta Margarete.
Genotoxicity studies on toxic metals and their organic compounds are very important, especially so in the investigation of the effects of these compounds on the aquatic environments where they tend to accumulate. The use of endemic aquatic organisms as biological sentinels has proved useful to environmental monitoring. We assessed the mutagenic potential of tributyltin (TBT) and inorganic lead (PbII) using samples of the fish Hoplias malabaricus (commonly called traíra) using the comet assay and the piscine micronucleus and chromosome aberration tests. Eighteen H. malabaricus were acclimatized in three individual aquariums, each containing six fish, six fish being exposed to 0.3 mg/g of body weight (bw) of TBT, six to 21 mg/g bw of PbII and six being used...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Comet assay; Micronucleus; Chromosome aberrations; Tributyltin; Lead; Fish.
Ano: 2004
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000100017

Sublethal and histopathological effects of trace levels of tributyltin fluoride on adult oysters Crassostrea gigas
Provedor de dados: 5
Autores: Chagot, Dominique; Alzieu, Claude; Sanjuan, Jane; Grizel, Henri.
Shell malformations and histological effects of environmental concentrations of TBTF (2, 13.1 and 64.8 ng/!) were assessed on adult oysters Crassostrea gigas during a I-month experiment, incIuding both an exposure and a depuration phase. The results showed that the digestive gland is the primary target organ. Recoverable modifications were observed at the lowest concentration. Limited necrosis was observed at the highest concentration and a longer exposure could have led to extensive and irreversible tissue lesions. Shell malformations (chambering) were observed during the depuration phase. Finally the authors suggest that safe TBT levels in mariculture waters should be lower than 2 ng/l.
Tipo: Text
Palavras-chave: Histopathological effects; Crassostrea gigas; Tributyltin; Effets histopathologiques; Crassostrea gigas; Tributylétain.
Ano: 1990
URL: http://archimer.ifremer.fr/doc/1990/publication-2754.pdf

First record of butyltin body burden and imposex status in Hexaplex trunculus (L.) along the Tunisian coast
Provedor de dados: 5
Autores: Lahbib, Youssef; Abidli, Sami; Chiffoleau, Jean-francois; Averty, Bernard; El Menif, Najoua Trigui.
We have assessed for the first time the current status of tributyltin (TBT) contamination in Hexaplex trunculus along Tunisian coastal waters. Two sampling campaigns have been performed in July 2004 and July 2007 at seven different sites. The snails were analyzed for imposex status, i.e. Imposex incidence, Relative Penis Length Index (RPLI) and Vas Deferens Sequence Index (VDSI), followed by the quantification of butyltins in their tissues. Imposex was detected in six populations from the 2004 samples and in five populations from the 2007 samples. The imposex incidence ranged from 0 (no imposex) to 100%, the RPLI from 0 to 56.7 and the VDSI from 0 to 4.4. TBT was also detected in six populations in 2004 and five populations in 2007. The concentrations...
Tipo: Text
Palavras-chave: Tunisia; Imposex; Hexaplex trunculus; TBT; Tributyltin.
Ano: 2009
URL: http://archimer.ifremer.fr/doc/2009/publication-6499.pdf

Bilan 1992 de la contamination des côtes françaises par les composés organostanniques
Provedor de dados: 5
Autores: Michel, Pierre; Averty, Bernard.
Au cours du printemps 1992, un échantillonnage systématique a permis d'évaluer le niveau de la contamination des côtes françaises par les composés organostanniques. Le tributyl étain (TBT) a été mesuré dans la phase dissoute avec ses produits de dégradation dibutyl étain (DBT) et monobutyl étain (MBT). Les concentrations mesurées restent importantes dans les zones portuaires et les zones de mélanges. Ces concentrations sont le plus souvent excessives lorsqu'on se réfère au seuil toxique de 1ng.1-1 pour lequel des effets sont connus sur l'huître et certains autres mollusques. Les trois façades maritimes françaises ont été contôlées ; c'est en Méditerranée que l'on peut observer les plus fortes concentrations. En plus du TBT et de ses métabolites, on a aussi...
Tipo: Text
Palavras-chave: Tributyl étain; Dibutyl étain; Monobutyl étain; Triphényl étain; Composés organostanniques; Eau de mer; France.; Tributyltin; Dibutyltin; Monobutyltin; Triphenyltin; Organotin compounds; Seawater; French coasts.
Ano: 1996
URL: http://archimer.ifremer.fr/doc/00104/21530/19111.pdf

Cultured heart cells from oyster: an experimental approach for evaluation of the toxicity of the marine pollutant tributyltin
Provedor de dados: 5
Autores: Droguet, Mickael; Devauchelle, Nicole; Pennec, Jean-pierre; Quinn, Brian; Dorange, Germaine.
European Community regulations on chemicals promote alternative methods to test substances presenting potential risks for the environment. In the present work, cultured atrial cells isolated from oyster (Crassostrea gigas) were used as an experimental model to investigate the toxicity of tributyltin (TBT) after short-time exposure at concentrations representative of those that can be measured in seawater, marine sediments and/or bivalves bioaccumulating this pollutant. In vitro and in vivo assays produce values of the same order of magnitude for both animal/cell survival and heart/cardiomyocyte beating rate. The survival rate of whole animals decreased from 10(-6) M TBT after 3 days. For cultured cells, the viability, evaluated using 3-(4,...
Tipo: Text
Palavras-chave: Oyster; Heart cells; Flow cytometry; Tributyltin; Toxicity; Antifouling.
Ano: 2012
URL: http://archimer.ifremer.fr/doc/00089/20032/17688.pdf

Tributyltin: A Bottom–Up Regulator of the Crangon crangon Population?
Provedor de dados: 5
Autores: Parmentier, Koen F. V.; Verhaegen, Yves; De Witte, Bavo P.; Hoffman, Stefan; Delbare, Daan H. R.; Roose, Patrick M.; Hylland, Ketil D. E.; Burgeot, Thierry; Smagghe, Guy J.; Cooreman, Kris.
The restrictions and the concerted action of the global ban on the use and presence of tributyltin (TBT) in marine applications to protect ecosystems in the marine environment in 2008 was mainly based on the economic impact on shellfish industries and the dramatic extinction of local mollusk populations in the past. In contrast to the vast datasets on effects on mollusks, the knowledge on impacts on species from other taxa remained in the uncertain until almost two decades ago. The assumption on a long-term TBT-mediated pernicious metabolic bottom–up regulation of the crustacean Crangon crangon population was provoked by the outcome of an EU-project ‘Sources, Consumer Exposure and Risks of Organotin Contamination in Seafood.’ This study reported high TBT...
Tipo: Text
Palavras-chave: Tributyltin; Crangon crangon; Endocrine disruption; Ecosystem impact; Ecdysteroids; Ecdysteroid receptor.
Ano: 2019
URL: https://archimer.ifremer.fr/doc/00585/69727/67617.pdf

Triorganotin as a compound with potential reproductive toxicity in mammals
Provedor de dados: 56
Autores: Delgado Filho,V.S.; Lopes,P.F.I.; Podratz,P.L.; Graceli,J.B.
Organotin compounds are typical environmental contaminants and suspected endocrine-disrupting substances, which cause irreversible sexual abnormality in female mollusks, called "imposex". However, little is known about the capability of triorganotin compounds, such as tributyltin and triphenyltin, to cause disorders in the sexual development and reproductive functions of mammals, including humans and rodents. Moreover, these compounds can act as potential competitive inhibitors of aromatase enzyme and other steroidogenic enzymes, affecting the reproductive capacity of male and female mammals. In this review, we discuss the cellular, biochemical, and molecular mechanisms by which triorganotin compounds induce adverse effects in the mammalian reproductive...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Tributyltin; Triphenyltin; Endocrine disruptor; Aromatase; Imposex; Mammalian reproductive organs.
Ano: 2011
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000900018