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6-Benzilaminopurina e ácido indolbutírico na multiplicação in vitro da amoreira - preta (Rubus idaeus L.), cv. Tupy Ciência Rural
Erig,Alan Cristiano; De Rossi,Andrea; Fortes,Gerson Renan de Luces.
O presente trabalho avaliou o efeito de diferentes níveis de BAP (0; 2; 4; 6; 8 e 10miM) e de AIB (0; 0,5 e 1miM) na multiplicação in vitro da amoreira-preta cv. Tupy. O meio utilizado foi o MS suplementado com 100mg.<IMG SRC="http:/img/fbpe/cr/v32n5/11864s1.gif">-1 de mio-inositol, 30g.<IMG SRC="http:/img/fbpe/cr/v32n5/11864s1.gif">-1 de sacarose e 6g.<IMG SRC="http:/img/fbpe/cr/v32n5/11864s1.gif">-1 de ágar. Após a inoculação, as culturas foram mantidas em sala de cultura com 16 horas de fotoperíodo, temperatura de 25 ± 2ºC e radiação de 25µmoles.m-2.s-1. O número de gemas e o número de brotações foram avaliados com intervalo semanal, num total de quatro avaliações, e, na última avaliação, considerou-se a altura da brotação, bem como...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Reguladores de crescimento; Micropropagação; Cultura de tecidos.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782002000500005
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6-Bromoindirubin-3’-oxime promotes osteogenic differentiation of canine BMSCs through inhibition of GSK3β activity and activation of the Wnt/β-catenin signaling pathway Anais da ABC (AABC)
ZHAO,XIAO-E; YANG,ZHENSHAN; GAO,ZHEN; GE,JUNBANG; WEI,QIANG; MA,BAOHUA.
This study aimed to investigate how 6-bromoindirubin-3’-oxime (BIO) increases the osteogenic differentiation of canine bone mesenchymal stem cells (BMSCs) and the role of the Wnt/β-catenin signaling pathway in this process. We mimicked the effect of Wnt by adding BIO to the culture medium of BMSCs and examined whether canonical Wnt signaling positively affects the differentiation of these cells into osteoblasts. Canine BMSCs were cultured with 0.5 and 1.0 μM BIO under osteogenic conditions and then differentiation markers were investigated. It was found that BIO significantly increased the activity of alkaline phosphatase (ALP), the number of ALP-positive cells, the mineralization level and calcium deposits. Moreover, cells cultured with 0.5 and 1.0 μM...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bone mesenchymal stem cells; Bromoindirubin oxime; Osteogenetic differentiation; Canine.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000100610
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6-Gingerol inhibits hair cycle via induction of MMP2 and MMP9 expression Anais da ABC (AABC)
HOU,CHUN; MIAO,YONG; JI,HANG; WANG,SUSHENG; LIANG,GANG; ZHANG,ZHIHUA; HONG,WEIJIN.
ABSTRACT 6-Gingerol is the major active constituent of ginger. In the current study, we aimed to investigate the mechanisms underlying the effects of 6-Gingerol on hair growth. Mice were randomly divided into five groups; after hair depilation (day 0), mice were treated with saline, or different concentrations of 6-Gingerol for 11 days. The histomorphological characteristics of the growing hair follicles were examined after hematoxylin and eosin staining. The results indicated that 6-Gingerol significantly suppressed hair growth compared with that in the control group. And choose the concentration of 6-Gingerol at 1 mg/mL to treated with mice. Moreover, 6-Gingerol (1 mg/mL) significantly reduced hair re-growth ratio, hair follicle number, and hair follicle...
Tipo: Info:eu-repo/semantics/article Palavras-chave: MMP2; MMP9; 6-Gingerol; Hair growth.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000602707
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6-n-propyltiouracil (PROP) taster status in Brazilian adults Ciênc. Tecnol. Aliment.
Von Atzingen,Maria Carolina Batista Campos; Silva,Maria Elisabeth Machado Pinto e.
The objective of this study was to determine PROP (6-n-propyltiouracil) taster status in adults and its relationship with anthropometric variables and pleasantness of sugar, salt, and fat. A total of 123 subjects rated the intensity of PROP and sodium cloride (NaCl) solutions using the labeled magnitude scale. For pleasantness evaluation, it was used concentrated orange juice (sugar) and mashed potato (salt and fat). The subjects were classified as non-tasters (n = 35), medium-tasters (n = 33) and super-tasters (n = 55). In this study, no relationship was found between PROP taster status and age, sex, weight, body mass index, and pleasantness. Although genetic markers may influence the degree of liking of certain foods, one must consider that the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Propylthiouracil; Body mass index; Pleasantness.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612012000400006
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6o Congresso Brasileiro de Agroinformática - SBIAgro 2007. Infoteca-e
TERNES, S..
2007
Tipo: Artigo de divulgação na mídia (INFOTECA-E) Palavras-chave: SBIAgro; Congresso.
Ano: 2007 URL: http://www.infoteca.cnptia.embrapa.br/handle/doc/7889
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70 years of development of Pharmaceutical Sciences: a lot to celebrate! BJPS
Aranha,Leila Rangel de Carvalho.
Tipo: Info:eu-repo/semantics/other
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000200001
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7-epi-griffonilide, a new lactone from Bauhinia pentandra: complete 1H and 13C chemical shift assignments Anais da ABC (AABC)
ALMEIDA,MACIA C.S. DE; SOUZA,LUCIANA G.S.; FERREIRA,DANIELE A.; PINTO,FRANCISCO C.L.; OLIVEIRA,DÉBORA R. DE; SANTIAGO,GILVANDETE M.P.; MONTE,FRANCISCO J.Q.; BRAZ-FILHO,RAIMUNDO; LEMOS,TELMA L.G. DE.
ABSTRACT A new lactone, 7-epi-griffonilide (1), and six known compounds, 2, 3a - 3c, 4a and 4b, were isolated from the leaves of Bauhinia pentandra (Fabaceae). The structures elucidation of 1 and 2 were based on detailed 2D NMR techniques and spectral comparison with related compounds, leading to complete assignment of the 1H and 13C NMR spectra.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bauhinia pentandra; Fabaceae; Cyanoglucoside; Lactones; RMN..
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000100065
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7-hydroxycalamenene effects on secreted aspartic proteases activity and biofilm formation of Candida spp. Repositório Alice
AZEVEDO, M. M. B.; ALMEIDA, C. A.; CHAVES, F. C. M.; RODRIGUES, I. A.; BIZZO, H. R.; ALVIANO, C. S.; ALVIANO, D. S..
The 7-hydroxycalamenenene-rich essential oil (EO) obtained from the leaves of Croton cajucara (red morphotype) have been described as active against bacteria, protozoa, and fungi species. In this work, we aimed to evaluate the effectiveness of 7-hydroxycalamenenene against Candida albicans and nonalbicans species.
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Croton cajucara; Anti-candidal activity; Essential oil; Óleo essencial; Secreted aspartic proteases.
Ano: 2016 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1040252
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7-pentoxyresorufin-o-depentilase and 7-Benzyloxyresorufin-o-debenzylase as potential biomarkers of exposure to 17B-estradiol in nile tilapia. Repositório Alice
BITTENCOURT, F. de O.; FRIGHETTO, R. T. S.; QUEIROZ, J. F. de; LOSEKANN, M. E.; LUIZ, A. J. B..
2009
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Biomarcadores; Poluição da água.
Ano: 2009 URL: http://www.alice.cnptia.embrapa.br/handle/doc/579352
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"80 anos a Serviço da Pátria" Anais da ESALQ
Lordello,Luiz Gonzaga E..
Tipo: Info:eu-repo/semantics/other
Ano: 1981 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0071-12761981000100001
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-866G/A and Ins/Del polymorphisms in the UCP2 gene and diabetic kidney disease: case-control study and meta-analysis Genet. Mol. Biol.
Dieter,Cristine; Assmann,Taís Silveira; Lemos,Natália Emerim; Massignam,Eloísa Toscan; Souza,Bianca Marmontel de; Bauer,Andrea Carla; Crispim,Daisy.
Abstract Uncoupling protein 2 (UCP2) decreases reactive oxygen species (ROS). ROS overproduction is a key contributor to the pathogenesis of diabetic kidney disease (DKD). Thus, UCP2 polymorphisms are candidate risk factors for DKD; however, their associations with this complication are still inconclusive. Here, we describe a case-control study and a meta-analysis conducted to investigate the association between UCP2 -866G/A and Ins/Del polymorphisms and DKD. The case-control study comprised 385 patients with type 1 diabetes mellitus (T1DM): 223 patients without DKD and 162 with DKD. UCP2 -866G/A (rs659366) and Ins/Del polymorphisms were genotyped by real-time PCR and conventional PCR, respectively. For the meta-analysis, a literature search was conducted...
Tipo: Info:eu-repo/semantics/article Palavras-chave: UCP2; Polymorphisms; Diabetic kidney disease.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572020000400101
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8-Propyl-6H-[1,3]dioxolo[4,5-g]chromen-6-one: A new coumarin with monoamine oxidase B inhibitory activity and possible anti-parkinsonian effects BJPS
Olaya,María del Pilar; Vergel,Nadezdha Esperanza; López,Jose Luis; Viña,Dolores; Guerrero,Mario Francisco.
Parkinson’s disease is a common neurodegenerative disorder. In this study, the monoamine oxidase inhibitory activity and potential anti-parkinsonian effects of 8-propyl-6H-[1,3]dioxolo[4,5-g]chromen-6-one (FCS303), a new synthetic coumarin, were evaluated. To do this, we used the reserpine model of Parkinson’s disease, an assay of levodopa/carbidopa potentiation, the catalepsy model of haloperidol, and an in vitro assay against monoamine oxidase (MAO) activity. Additionally, lipid peroxidation and protein carbonyl group quantification was performed in mice brain homogenates previously treated with haloperidol. FCS303 inhibited monoamine oxidase B (MAO-B) with an IC50 of 5.46 ± 0.36 µM; however, there was no effect on monoamine oxidase A (MAO-A). The oral...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Parkinson’s disease; Monoamine oxidase B; Coumarin; Mice; Reserpine; Levodopa; Carbidopa.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100508
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A 15-year post evaluation of the fire effects on ant community in an area of Amazonian forest Rev. Bras. entomol.
Santos,Jean C.; Delabie,Jacques H. C.; Fernandes,G. Wilson.
Fire represents an important disturbance to ant communities in areas of fire regime. Otherwise, little is known about the effects of fire on ant communities in areas of non-fire regimes, such as in the Amazonian region. We evaluated the long-term effect of fire on ant species richness in a rain forest (Bacaba Plateau) burned 15-years ago and compare our data with the data of primary unburned forest. A total of 85 ant species distributed in 21 genera and 14 tribes were collected; among them, 72 and 44 species were found on the litter and vegetation, respectively. The fire damaged forest studied supports an intermediate richness of ants when compared to a primary unburned rain forest in the same region. A comparative analysis of ant species richness showed...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Amazon; Brazil; Community structure; Rain forest; Species richness.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0085-56262008000100015
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A 19-year old man with IgA vasculitis after vaccination BJID
Malek,Alexandre; Gomez-Villegas,Sara Isabel; de la Hoz,Alejandro; Nowbakht,Cima; Arias,Cesar A..
ABSTRACT A 19-year-old patient who mistakenly received two doses of influenza vaccine 10 days before presentation, was admitted with malaise, weakness, and a purpuric non-blanching rash most prominent on the ankles followed by abdominal pain and hematochezia 72 h later. The diagnosis of influenza vaccine-related Henoch–Schonlein vasculitis was made. This complication, although rare, is the most common vasculitis related to immunization.
Tipo: Info:eu-repo/semantics/report Palavras-chave: Influenza vaccination; Immunization; IgA vasculitis; Henoch–Schonlein purpura.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000500442
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A 2,2' - dipiridil cetoxima, como reagente para determinação espectrofotométrica do cobalto Anais da ESALQ
Jacintho,Antonio Octavio.
A presente nota relata alguns aspectos dos estudos preliminares sobre a aplicação da 2,2' - dipiridil cetoxima como reagente para a determinação colorimétrica do cobalto. Nesta oportunidade, procurou-se principalmente analisar os problemas decorrentes da aplicação da técnica descrita por HOLLAND &amp; BOZIC (1968), na determinação do cobalto em plantas.
Tipo: Info:eu-repo/semantics/article
Ano: 1972 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0071-12761972000100002
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A 28-fold increase in secretory protein synthesis is associated with DNA puff activity in the salivary gland of Bradysia hygida (Diptera, Sciaridae) BJMBR
When the first group of DNA puffs is active in the salivary gland regions S1 and S3 of Bradysia hygida larvae, there is a large increase in the production and secretion of new salivary proteins demonstrable by [3H]-Leu incorporation. The present study shows that protein separation by SDS-PAGE and detection by fluorography demonstrated that these polypeptides range in molecular mass from about 23 to 100 kDa. Furthermore, these proteins were synthesized mainly in the S1 and S3 salivary gland regions where the DNA puffs C7, C5, C4 and B10 are conspicuous, while in the S2 region protein synthesis was very low. Others have shown that the extent of amplification for DNA sequences that code for mRNA in the DNA puffs C4 and B10 was about 22 and 10 times,...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Gene amplification; Secretory polypeptide synthesis; DNA puffs; Salivary glands of Sciaridae.
Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000500006
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A 2D-QSPR approach to predict blood-brain barrier penetration of drugs acting on the central nervous system BJPS
Sá,Matheus Malta de; Pasqualoto,Kerly Fernanda Mesquita; Rangel-Yagui,Carlota de Oliveira.
Drugs acting on the central nervous system (CNS) have to cross the blood-brain barrier (BBB) in order to perform their pharmacological actions. Passive BBB diffusion can be partially expressed by the blood/brain partition coefficient (logBB). As the experimental evaluation of logBB is time and cost consuming, theoretical methods such as quantitative structure-property relationships (QSPR) can be useful to predict logBB values. In this study, a 2D-QSPR approach was applied to a set of 28 drugs acting on the CNS, using the logBB property as biological data. The best QSPR model [n = 21, r = 0.94 (r² = 0.88), s = 0.28, and Q² = 0.82] presented three molecular descriptors: calculated n-octanol/water partition coefficient (ClogP), polar surface area (PSA), and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Two-dimensional quantitative structure-property relationships (2D-QSPR); Calculated n-octanol/water partition coefficient (ClogP); Blood-brain barrier; Benzodiazepines.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000400016
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A 37-kb restriction map of the human immunoglobulin lambda variable locus, VB cluster, harboring four functional genes and two non-coding Vl sequences Braz. J. Genet.
Passos Jr.,Geraldo A.S.; Lefranc,Marie-Paule.
The human immunoglobulin lambda variable locus (IGLV) is mapped at chromosome 22 band q11.1-q11.2. The 30 functional germline v-lambda genes sequenced untill now have been subgrouped into 10 families (V<FONT FACE="Symbol">l</font>1 to V<FONT FACE="Symbol">l</font>10). The number of V<FONT FACE="Symbol">l</font> genes has been estimated at approximately 70. This locus is formed by three gene clusters (VA, VB and VC) that encompass the variable coding genes (V) responsible for the synthesis of lambda-type Ig light chains, and the J<FONT FACE="Symbol">l</font>-C<FONT FACE="Symbol">l</font> cluster with the joining segments and the constant genes. Recently the entire variable lambda gene locus was...
Tipo: Info:eu-repo/semantics/article
Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-84551997000400027
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A 3K Axiom SNP array from a transcriptomewide SNP resource sheds new light on the genetic diversity and structure of the iconic subtropical conifer tree Araucaria angustifolia (Bert.) Kuntze. Repositório Alice
SILVA, P. I. T.; SILVA JUNIOR, O. B.; RESENDE, L. V.; SOUSA, V. A.; AGUIAR, A. V.; GRATTAPAGLIA, D..
High-throughput SNP genotyping has become a precondition to move to higher precision and wider genome coverage genetic analysis of natural and breeding populations of non-model species. We developed a 44,318 annotated SNP catalog for Araucaria angustifolia, a grandiose subtropical conifer tree, one of the only two native Brazilian gymnosperms, critically endangered due to its valuable wood and seeds. Following transcriptome assembly and annotation, SNPs were discovered from RNA-seq and pooled RAD-seq data. From the SNP catalog, an Axiom® SNP array with 3,038 validated SNPs was developed and used to provide a comprehensive look at the genetic diversity and structure of 15 populations across the natural range of the species. RNA-seq was a far superior source...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Araucária Angustifólia.
Ano: 2020 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1124676
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A 7-year survey of superficial and cutaneous mycoses in a public hospital in Natal, Northeast Brazil BJM
Calado,Nicácia Barbosa; Sousa Júnior,Francisco Canindé de; Diniz,Mariana Guimarães; Fernandes,Ana Cristina Santos; Cardoso,Fernando José Ramos; Zaror,Luiz Conrado; Ferreira,Maria Ângela Fernandes; Milan,Eveline Pipolo.
In the present study, we determined the frequency of superficial and cutaneous mycoses and their etiologic agents during a 7-year period (2002-2008) in Natal, Brazil. A total of 1,717 specimens of skin, nail, and hair were collected from 1,382 patients with suspected mycoses lesions and were then subjected to direct microscopy and culture.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cutaneous mycoses; Dermatophytes; Fungal infections; Yeasts; Superficial mycoses.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822011000400008
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