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| Ebaid,Hossam; Abdel-Salam,Bahaa; Alhazza,Ibrahim; Al-Tamimi,Jameel; Hassan,Iftekhar; Rady,Ahmed; Mashaly,Ashraf; Mahmoud,Ahmed; Sammour,Reda. |
| Abstract Background: Ant venoms express surface molecules that participate in antigen presentation involving pro- and anti-inflammatory cytokines. This work aims to investigate the expression of MHC-II, CD80 and CD86 on the polymorphonuclear cells (PMNs) in rats injected with samsum ant venom (SAV). Methods: Rats were divided into three groups - control, SAV-treated (intraperitoneal route, 600 μg/kg), and SAV-treated (subcutaneous route, 600 μg/kg). After five doses, animals were euthanized and samples collected for analysis. Results: The subcutaneous SAV-trated rats presented decreased levels of glutathione with increased cholesterol and triglyceride levels. Intraperitoneal SAV-treated animals displayed significantly reduced concentrations of both... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Samsum ant venom; Polymorphonuclear cells (PMNs); Costimulatory molecules (CD80 and CD86); Major histocompatibility complex (MHC); MHC-II; Interferon gamma (INF-γ); Interleukin-17 (IL-17). |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992019000100208 |
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