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Registros recuperados: 38
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Bioactive peptides from marine sources: pharmacological properties and isolation procedures OceanDocs
Aneiros, A.; Garateix, A..
Marine organisms represent a valuable source of new compounds. The biodiversity of the marine environment and the associated chemical diversity constitute a practically unlimited resource of new active substances in the field of the development of bioactive products. In this paper, the molecular diversity of different marine peptides is described as well as information about their biological properties and mechanisms of action is provided. Moreover, a short review about isolation procedures of selected bioactive marine peptides is offered. Novel peptides from sponges, ascidians, mollusks, sea anemones and seaweeds are presented in association with their pharmacological properties and obtainment methods.
Tipo: Journal Contribution Palavras-chave: Marine environment; Marine organisms; Peptides; Bioactive compounds; Marine environment; Peptides; Http://aims.fao.org/aos/agrovoc/c_4610; Http://aims.fao.org/aos/agrovoc/c_5691.
Ano: 2004 URL: http://hdl.handle.net/1834/2921
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Antimicrobial activity and bioactive compounds of portuguese wild edible mushrooms methanolic extracts IPB - Escola Superior Agrária
Barros, Lillian; Calhelha, Ricardo C.; Vaz, Josiana A.; Ferreira, Isabel C.F.R.; Baptista, Paula; Estevinho, Leticia M..
The antimicrobial properties of phenolic extracts of Portuguese wild edible mushroom species (Lactarius deliciosus, Sarcodon imbricatus and Tricholoma portentosum) against pathogens were investigated. The minimal inhibitory concentrations (MICs) were evaluated for the entire mushroom, the cap and the stipe, separately; the portion of the mushroom used proved to be influenced in the results obtained, which are directly correlated with the content of total phenols and flavonoids in the extracts. The growth of Grampositive bacteria (Bacillus cereus, B. subtilis,) was well inhibited by these mushrooms, while Escherichia coli (Gramnegative bacteria) was resistant. The study on the antifungal effect of these mushrooms revealed that Candida albicans and...
Tipo: Article Palavras-chave: Wild edible mushrooms; Bioactive compounds; Antimicrobial activity.
Ano: 2007 URL: http://hdl.handle.net/10198/829
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Folk medicine of Trás-os-Montes (Portugal). Traditional uses and bioactive compounds of six common medicinal species IPB - Escola Superior Agrária
Carvalho, Ana Maria; Barros, Lillian; Ferreira, Isabel C.F.R.; Frazão-Moreira, Amélia.
Ethnobotanical surveys conducted in north-eastern Portugal along several years (2000-2009) reported plant knowledge and use of almost 150 wild species used in folk medicine. This poster documents traditional knowledge and reports the first approach to the antioxidant potential evaluation of six of these species with particular cultural significance, accessed by biochemical assays used as models for the lipid peroxidation damage in biomembranes. Bioactive compounds such as phenolics, flavonoids, vitamin C and vitamin E were also determined.
Tipo: Other Palavras-chave: Portuguese ethnobotany; Etnobotânica portuguesa; MAP; PAM; Phytochemicals; Bioactive compounds; TEK; Plantas e saberes.
Ano: 2009 URL: http://hdl.handle.net/10198/3773
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Antibacterial activity of Falkenbergia hillebrandii (Born) from the Indian coast against human pathogens Phyton
Manilal,A; Sujith,S; Selvin,J; Shakir,C; Seghal Kiran,G.
The antibacterial property of the red algae, Falkenbergia hillebrandii (Born) collected from the southwest coast of India (Indian Ocean) was evaluated against three multidrug resistant human pathogens. Four different solvents: ethyl acetate, dichloromethane, methanol and phosphate buffer saline (PBS) were used with this purpose. Dried samples extracted with methanol showed broadest and highest antimicrobial activity when compared to other solvents. However, PBS extract showed no antibacterial activity. The highly active compounds red alga, F. hillebrandii were fractionated and purified using different chromatographic systems, including reverse phase HPLC and GCMS. The analysis revealed that the most abundant metabolite was the oleic acid (51.33%) followed...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antimicrobial activity; F. hillebrandii; Multidrug resistant human pathogens; Methanolic extract; Bioactive compounds.
Ano: 2009 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1851-56572009000200013
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Bioactive compounds and total antioxidant activity during the development of sapodilla fruit. Repositório Alice
OLIVEIRA, L. S.; RODRIGUES, D. da C.; MOURA, C. F. H.; MIRANDA, M. R. A..
2010
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Bioactive compounds; Antioxidant activity; Sapodilla fruit.
Ano: 2010 URL: http://www.alice.cnptia.embrapa.br/handle/doc/882353
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Quality, bioactive compounds and antioxidant activity in fruits of a seedless peach palm selection from Acre, Brazil. Repositório Alice
MATOS, N. M. dos S.; FAÇANHA, R. V.; SOUZA, K. O. de; RUFINO, M. do S. M.; ALVES, R. E.; BRITO, E. S. de; ALVARES, V. de S.; MACIEL, V. T..
2010
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Quality; Bioactive compounds; Antioxidant activity; Seedless peach palm.
Ano: 2010 URL: http://www.alice.cnptia.embrapa.br/handle/doc/882826
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Influence of the Genotype on the Anthocyanin Composition, Antioxidant Capacity and color of Chilean Pomegranate (Punica granatum L.) Juices Chilean J. Agric. Res.
Sepúlveda,Elena; Sáenz,Carmen; Peña,Álvaro; Robert,Paz; Bartolomé,Begoña; Gómez-Cordovés,Carmen.
The bioactive compounds content in pomegranate (Punica granatum L.) juice is variable and depends on agronomic factors, genetic and fruit maturity. In Chile, the areas with this crop have increased more than 65% in the last 5 years. This paper aims to determine the phenolic composition, antioxidant capacity and chromatic parameters of juices from eight Chilean pomegranate genotypes (PG2 to PG9), containing red (PG2 to PG6) or pink arils (PG7 to PG9). Color, total polyphenol content (using Folin-Ciocalteu reagent), total anthocyanins (by differences in absorbance at different pHs of the juice) and antioxidant capacity (oxygen-radical absorbance capacity, ORAC) were determined. Anthocyanins were identified and quantify using HPLC-DAD and HPLC/ESI-MS, the...
Tipo: Journal article Palavras-chave: Polyphenols; Bioactive compounds.
Ano: 2010 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-58392010000100005
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Fertilización orgánica e inorgánica en la producción y calidad de aceites esenciales en manzanilla, menta y tomillo. Colegio de Postgraduados
Juárez Rosete, Cecilia Rocío.
Dentro de los factores agronómicos que tienen un efecto en el incremento de la productividad de los cultivos y que maximizan su potencial durante su desarrollo, la fertilización es uno de los más importantes. En plantas aromáticas y medicinales se ha demostrado que influye en el crecimiento, eleva el rendimiento de biomasa y juega un papel crucial en las características fitoquímicas de estas. Los objetivos generales de esta investigación fueron evaluar el efecto de la fertilización orgánica e inorgánica sobre el crecimiento y sobre las características cualitativas y cuantitativas de aceites esenciales en manzanilla (Chamomilla recutita L.), menta (Mentha x pipperita L.) y tomillo (Thymus vulgaris L.) cultivadas bajo condiciones de invernadero; y evaluar...
Palavras-chave: Fertilización; Rendimiento; Plantas aromáticas; Compuestos bioactivos; Fertilization; Yield; Herbs; Bioactive compounds; Doctorado; Edafología.
Ano: 2010 URL: http://hdl.handle.net/10521/107
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Inhibition of shrimp pathogenic vibrios by extracellular compounds from a proteolytic bacterium Pseudomonas sp. W3 Electron. J. Biotechnol.
Rattanachuay,Pattamarat; Kantachote,Duangporn; Tantirungkij,Manee; Nitoda,Teruhiko; Kanzaki,Hiroshi.
Pseudomonas sp. W3, a bacterium known to produce an extracellular alkaline protease, secreted secondary metabolites that inhibited pathogenic bacteria responsible for shrimp luminous vibriosis disease. Antivibrio compounds in the culture supernatant or culture filtrates (0.45 µm and 0.22 µm) of the isolate W3 were tested using an agar well diffusion method on a number of pathogenic vibrios. Vibrio harveyi PSU 2015 a pathogenic isolate was the most sensitive strain. The effectiveness of preparations from the isolate W3 against V. harveyi PSU 2015, and V. cholerae PSSCMI 0062 was in the order of culture supernatant > 0.45 µm culture filtrate > 0.22 µm culture filtrate. These extracellular antivibrio compounds also lysed both dead and living cells of V....
Tipo: Journal article Palavras-chave: Bacteriolytic enzymes; Bioactive compounds; Pseudomonas sp. W3; Shrimp pathogenic bacteria; Vibrio spp.
Ano: 2010 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582010000100008
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Studies on chemical constituents and bioactivity of Rosa micrantha: an alternative antioxidants source for food, pharmaceutical, or cosmetic applications IPB - Escola Superior Agrária
Guimarães, Rafaela; Barros, Lillian; Carvalho, Ana Maria; Ferreira, Isabel C.F.R..
Rose species have long been used for food and medicinal purposes. Rosa micrantha is one of the rose species that grow feral in the northeastern Portuguese region so-called Nordeste Transmontano. For the first time, chemical composition and bioactivity of their petals, fertilized flowers, unripe, ripening, and overripe hips were evaluated in order to valorize them as sources of important phytochemicals. Chemical characterization included determination of proteins, fats, ash, and carbohydrates, particularly sugars, by HPLC-RI, fatty acids by GC-FID, tocopherols by HPLCfluorescence, and phenolics, flavonoids, carotenoids, and ascorbic acid by spectrophotometric techniques. Bioactivity was evaluated through screening of antioxidant properties: radical...
Tipo: Article Palavras-chave: Rosa micrantha; Hips; Flowers; Bioactive compounds; Applications; Portuguese ethnobotany.
Ano: 2010 URL: http://hdl.handle.net/10198/2645
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Contribution to the phytochemical study and biological activity of plants of Cuban flora OceanDocs
Nogueiras, C.; Spengler, I.; Guerra, J.O.; Ortiz, Y.; Torres, S.; García, T.H.; Romeu, C.R.; Regalado, E.L.; González, T.A.; Perera, W.H.; Lacret, R..
Interest in natural products as a source for innovation in drug discovery and agrochemicals is still growing worldwide. Natural products, whose immense diversity has been appreciated for many years, may become in a rich source of novel chemical structures. Our country is a rich source of both biological and chemical diversity which may be useful as a source of novel chemical structures. Even when natural products have been used as medicinal agents for many years in Cuba, their use as agrochemicals are still limited. Thus, the present review focuses on recent advances in the studies on natural products performed by the “Centro de Estudios de Productos Naturales, CEPN” during the past ten years, highlighting on those with potential use as biomedical...
Tipo: Journal Contribution Palavras-chave: Products; Chemical compounds; Bioactive compounds; Products; Chemical compounds; Http://aims.fao.org/aos/agrovoc/c_6211; Http://aims.fao.org/aos/agrovoc/c_49870.
Ano: 2010 URL: http://hdl.handle.net/1834/3986
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Marine sponges as a source of new bioactive substances OceanDocs
Regalado, E.L.; Laguna, A.; Martínez, J.R..
Las esponjas marinas (Porifera) han atraído la atención de un gran número de científicos alrededor del mundo. Estos animales y sus simbiontes utilizan mecanismos de defensa química, basados en la producción de compuestos biologicamente activos que utlizan para protegerse de posibles depredadores. Son considerados una mina de oro para los químicos y se han descubierto más de 6000 estructuras novedosas, muchas de ellas con enormes aplicaciones biomédicas, fundamentalmente contra el cáncer, pero también contra diversas bacterias, virus y otras enfermedades. Algunos de los fármacos derivados de esponjas se encuentran disponibles en el mercado, tal es el caso Ara-A (antiviral) y de la Ara-C (antitumoral), pero existen diversos compuestos bioactivos en...
Tipo: Journal Contribution Palavras-chave: Sponges; Chemical compounds; Bioactive compounds; Chemical compounds; Sponges; Http://aims.fao.org/aos/agrovoc/c_49870; Http://aims.fao.org/aos/agrovoc/c_7321.
Ano: 2010 URL: http://hdl.handle.net/1834/4039
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Topical anti-inflammatory plant species: bioactivity of Bryonia dioica, Tamus communis and Lonicera peryclimenum fruits IPB - Escola Superior Agrária
Rafael, Marco; Barros, Lillian; Carvalho, Ana Maria; Ferreira, Isabel C.F.R..
The practice of rubbing different plant material juices or extracts into the skin to relieve pain and rheumatic symptoms is deeply rooted in folk medicine and has been used for a long time. Several common species, usually available in agroecosystems of the Iberian Peninsula, were/are used for topical medicinal preparations as reported in recent ethnobotanical surveys. Based on these studies, the fruits of three relevant species (Bryonia dioica or white-bryony, Lonicera periclymenum or common honeysuckle and Tamus communis or black-bryony) were gathered and different analyses and assays were performed in order to characterize their phytochemical composition and to find biologically active compounds for pharmaceutical application. Black-bryony ripened fruits...
Tipo: Article Palavras-chave: Medicinal fruits; Topical anti-inflammatory; Antioxidant properties; Bioactive compounds; Portuguese ethnobotany.
Ano: 2011 URL: http://hdl.handle.net/10198/6066
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Towards the antioxidant and chemical characterization of mycorrhizal mushrooms from Northeast Portugal IPB - Escola Superior Agrária
Reis, Filipa S.; Heleno, Sandrina A.; Barros, Lillian; Sousa, Maria João; Martins, Anabela; Santos-Buelga, Celestino; Ferreira, Isabel C.F.R..
Mushrooms are widely appreciated all over the world for their nutritional properties and pharmacological value as sources of important bioactive compounds. Mycorrhizal macrofungi associate with plant roots constituting a symbiotic relationship. This symbiosis could influence the production of secondary metabolites, including bioactive compounds. We focused on the evaluation of antioxidant potential and chemical composition of mycorrhizal mushrooms species from Northeast Portugal: Amanita caesarea, Amanita muscaria, Amanita pantherina, Chroogomphus fulmineus, Cortinarius anomalus, Cortinarius collinitus, Cortinarius violaceus, Lactarius quietus, Lactarius volemus, Russula sardonia, Suillus luteus and Tricholoma ustale. A similar profile of metabolites was...
Tipo: Article Palavras-chave: Mycorrhizal mushrooms; Antioxidant activity; Nutrients; Bioactive compounds.
Ano: 2011 URL: http://hdl.handle.net/10198/6251
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Chemical composition of wild edible mushrooms and antioxidant properties of their water soluble polysaccharidic and ethanolic fractions IPB - Escola Superior Agrária
Vaz, Josiana A.; Barros, Lillian; Martins, Anabela; Santos-Buelga, Celestino; Vasconcelos, M. Helena; Ferreira, Isabel C.F.R..
Mushrooms have become attractive as functional foods and as a source of physiologically beneficial bioactive compounds. Herein, we describe and compare the chemical constituents (phenolic compounds, macronutrients, sugars, fatty acids, tocopherols and ascorbic acid) of four wild edible mushrooms widely appreciated in gastronomy: Armillaria mellea (Vahl) P. Kumm, Calocybe gambosa (Fr.) Donk, Clitocybe odora (Fr.) P. Kumm., Coprinus comatus (O.F. Müll.) Pers. Furthermore, the antioxidant activity of their water soluble polysaccharidic and ethanolic fractions was studied by three different in vitro assays. Coprinus comatus revealed the highest concentrations of sugars (43.23 g/100 g dry weight), PUFA (77.46%), phenolic compounds (45.02 mg/Kg), tocopherols...
Tipo: Article Palavras-chave: Wild edible mushrooms; Bioactive compounds; Phenolic compounds; Polysaccharides; Chemical composition.
Ano: 2011 URL: http://hdl.handle.net/10198/3881
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Apple extract: cytotoxicity and dna protection. Repositório Alice
VIZZOTTO, M.; FERRI, N. M. L.; BIALVES, T. S.; ARAUJO, V. F.; PEREIRA, E. dos S.; KROLOW, A. C. R..
2013
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Bioactive compounds; Crystal violet; Comet assay.
Ano: 2013 URL: http://www.alice.cnptia.embrapa.br/handle/doc/983037
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Microencapsulation of maqui (Aristotelia chilensis Molina Stuntz) leaf extracts to preserve and control antioxidant properties Chilean J. Agric. Res.
Vidal J,Leslie; Avello L,Marcia; Loyola C,Cristina; Campos P,Jorge; Aqueveque M,Pedro; R. Dungan,Stephanie; Galotto L,Maria; Guarda M,Abel.
Microencapsulation technology is an alternative to stabilize stress factors and protect food ingredients or additives, which include environmentally sensitive bioactive principles in protective matrices to increase their functionality and life span. The objective of this research was to study conditions to obtain microcapsules with antioxidant capacity from a maqui (Aristotelia chilensis [Molina] Stuntz, Elaeocarpaceae) leaf extract by emulsification and subsequent retention after microencapsulation. Microcapsules were produced by water-in-oil emulsion (W/O) using a phase of the aqueous maqui leaf extract and gum arabic, and a liquid vaseline phase. Maqui leaf extract antioxidant capacity was 99.66% compared with the aqueous phase of the emulsion at 94.38...
Tipo: Journal article Palavras-chave: Maqui; Antioxidant capacity; Bioactive compounds; Gum arabic.
Ano: 2013 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-58392013000100003
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Phenolic Compounds, Organic Acids and Antioxidant Activity of Grape Juices Produced in Industrial Scale by Different Processes of Maceration. Repositório Alice
LIMA, M. dos S.; DUTRA, M. da C. P.; TOALDO, I. M.; CORREA, L. C.; PEREIRA, G. E.; OLIVEIRA, D. de.; BORDIGNON-LUIZ, M. T.; NINOW, J. L..
2015
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Bioactive compounds; Pectinases; Suco de uva; Grape juice; Vitis labrusca.
Ano: 2015 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1023598
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Bioactive compounds of juices from two Brazilian grape cultivars. Repositório Alice
SILVA, J. K.; CAZARIN, C. B. B.; CORREA, L. C.; BATISTA, A. G.; FURLAN, C. P. B; BIASOTO, A. C. T.; PEREIRA, G. E.; CAMARGO, A. C. de; MARÓSTICA JUNIORA, M. R..
Grape juice consumption may prevent several chronic diseases owing to the presence of phenolic compounds, which have an important role in the reduction of oxidative stress. This study investigated the polyphenol content and antioxidant activities of grape juices from two cultivars: BRS-Cora and Isabella. Total polyphenol content (TPC), anthocyanins, antioxidant capacity (oxygenradical absorbance capacity, ferric reducing antioxidantpower and1,1-diphenyl-2-picrylhydrazyl), and phenolic profile (high-performance liquid chromatography with diode array and fluorescence detection ? HPLC-DAD-FLD) were determined.
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Variedade Isabella; BRS-Cora; Uva; Suco de uva; Polifenóis; Potencial antioxidante; Compostos bioativos; Grape juice; Polyphenols; Antioxidant potential; Bioactive compounds.
Ano: 2015 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1036811
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Phenolic compounds profile and antioxidant activity of commercial tropical red wines (Vitis vinifera L.) from São Francisco Valley, Brazil. Repositório Alice
PADILHA, C. V. da S.; BIASOTO, A. C. T.; CORREA, L. C.; LIMA, M. dos S.; PEREIRA, G. E..
Abstract The aim of this study was to investigate the phenolic composition and antioxidant activity of commercial red wines produced from Vitis vinifera L. grapes grown in the S~ao Francisco Valley (SFV), which is a tropical region in northeastern Brazil. All wines showed phenolic compound contents consistent with those of other traditional wine producing regions and high antioxidant activity. In total, 20 phenolic compounds were quantified by RP-HPLC-DAD-FD and the antioxidant activity was positively correlated with the content of syringic acid>peonidin 3-O-glucoside>q-coumaric acid>(1)-catechin, epigallocatechin gallate>cyanidin-3-O-glucoside>procyanidin A2>(-)-epicatechin, highlighting the contribution of these bioactive compounds to...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Antioxidant capacity; Bioactive compounds; Tropical wines.
Ano: 2016 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1059855
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