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| Cierco-Ayrolles, C.; Dejean, C.; Legarra, A.; Gilbert, H.; Druet, T.; Ytournel, F.; Estivals, D.; Oumouhou, N.; Mangin, B.. |
| BACKGROUND: Since 2001, the use of more and more dense maps has made researchers aware that combining linkage and linkage disequilibrium enhances the feasibility of fine-mapping genes of interest. So, various method types have been derived to include concepts of population genetics in the analyses. One major drawback of many of these methods is their computational cost, which is very significant when many markers are considered. Recent advances in technology, such as SNP genotyping, have made it possible to deal with huge amount of data. Thus the challenge that remains is to find accurate and efficient methods that are not too time consuming. The study reported here specifically focuses on the half-sib family animal design. Our objective was to determine... |
| Tipo: Journal Article |
Palavras-chave: PROBABILISTIC MODELLING; LINKAGE DISEQUILIBRIUM; QTL; SNP; MARKER; GENETIC; PEDIGREE. |
| Ano: 2010 |
URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD2010dbb9309f&uri=/notices/prodinra1/2010/12/ |
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