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| Registros recuperados: 27 | |
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| Lecuit, M.; Sonnenburg, J. L.; Cossart, P.; Gordon, J. I.. |
| Members of the genus Listeria provide a model for defining host responses to invasive foodborne enteropathogens. Active translocation of Listeria monocytogenes across the gut epithelial barrier is mediated by interaction of bacterial internalin (InlA) and its species-specific host receptor, E-cadherin, whereas translocation across Peyer’s patches through M-cells is InlA independent. To define microbial determinants and molecular correlates of the host response to translocation via these two routes, we colonized germ-free transgenic mice expressing the human enterocyte-associated E-cadherin receptor with wildtype (WT) or mutant L. monocytogenes strains, or its nonpathogenic noninvasive relative Listeria innocua, or with Bacteroides thetaiotaomicron, a... |
| Tipo: Journal Article |
Palavras-chave: LISTERIA MONOCYTOGENES; CADHERINE; BARRIERE INTESTINALE; LAMINA PROPRIA; PROTEINE BACTERIENNE; INTESTIN; MODELE ANIMAL; SOURIS; INFECTION; ENTEROPATHOGENE; MUTATION; EXPRESSION DES GENES; REPONSE IMMUNITAIRE; IMMUNITE. |
| Ano: 2007 |
URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD200924d16b14&uri=/notices/prodinra1/2010/11/ |
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| Registros recuperados: 27 | |
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