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Registros recuperados: 6
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Androgen and estrogen treatments alter steady state messengers RNA (mRNA) levels of testicular steroidogenic enzymes in the rainbow trout, Oncorhynchus mykiss Animal Physiology
Baron, D.; Fostier, A.; Breton, B.; Guiguen, Y..
Recent investigations have shown that estrogens have profound inhibitory effects on steroidogenic enzyme gene expressions before and after testicular differentiation in the rainbow trout, Oncorhynchus mykiss. This present study bring new data on juvenile rainbow trout treated with estrogens and androgens. Following a 8 days oral treatment of juvenile male with 17-ethynyl-estradiol (EE2, 20 mg/kg diet) or 11-hydroxyandrostenedione (11OH4, 10 mg/kg diet), we observed a fast and marked decrease of steady-state mRNA levels for 3HSD, P450scc, P450c17, and P450c11 enzymes in the testis. After completion of these treatments, mRNA levels of these enzymes remained low in EE2 treated males whereas in 11OH4 treated males they recovered their initial levels in 8 days....
Tipo: Journal (Paginated) Palavras-chave: QP Physiology.
Ano: 2005 URL: http://phy043.tours.inra.fr:8080/archive/00000087/
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Androgen-induced masculinization in rainbow trout results in a marked dysregulation of early gonadal gene expression profiles Animal Physiology
Baron, D.; Montfort, J.; Houlgatte, R.; Fostier, A.; Guiguen, Y..
Fish gonadal sex differentiation is affected by sex steroids treatments providing an efficient strategy to control the sexual phenotype of fish for aquaculture purposes. However, the biological effects of such treatments are poorly understood. The aim of this study was to identify the main effects of an androgen masculinizing treatment (11β-hydroxyandrostenedione, 11βOHΔ4, 10 mg/kg of food for 3 months) on gonadal gene expression profiles of an all-female genetic population of trout. To characterize the most important molecular features of this process, we used a large scale gene expression profiling approach using rainbow trout DNA microarrays combined with a detailed gene ontology (GO) analysis. 2,474 genes were characterized as up-regulated or...
Tipo: Journal (On-line/Unpaginated) Palavras-chave: QP Physiology.
Ano: 2007 URL: http://phy043.tours.inra.fr:8080/archive/00000431/
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Androgen-induced masculinization in rainbow trout results in a marked dysregulation of early gonadal gene expression profiles Inra
Baron, D.; Monfort, J.; Houlgatte, R.; Fostier, A.; Guiguen, Y..
Tipo: Journal Article Palavras-chave: STEROIDE; DIFFERENCIATION SEXUELLE; ANDROGENE; EXPRESSION DES GENES; TRAITEMENT HORMONAL; MASCULINISATION.
Ano: 2007 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD200734656080&uri=/notices/prodinra1/2007/12/
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Characterization of early molecular sex differentiation in rainbow trout, Oncorhynchus mykiss Animal Physiology
Vizziano, D.; Randuineau, G.; Baron, D.; Cauty, C.; Guiguen, Y..
Early differentiation in rainbow trout gonads was investigated by expression profiling and in situ hybridization (ISH). Expression of cyp19a1 and fst in females and sox9a1 in males were sexually dimorphic between 32 to 35 days post-fertilization (dpf). After 35 dpf, differentiation proceeded with sexually dimorphic profiles for sox9a2, dmrt1, cyp11b2.1, amh in males and foxl2a, foxl2b, hsd3b1, inha in females. cyp17a1, cyp11a1, star, nr5a1b increased only after 40 dpf in both sexes with a slightly higher expression in females. cyp19a1 expression was localized in a cluster of somatic cells in the ventral side of female gonads, and sox9a2 and amh in somatic cells surrounding the germ cells, at 28 dpf and thereafter, both in male and female gonads. cyp11b2.1,...
Tipo: Journal (Paginated) Palavras-chave: QP Physiology.
Ano: 2007 URL: http://phy043.tours.inra.fr:8080/archive/00000401/
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Foxl2 gene and the development of the ovary: a story about goat, mouse, fish and woman Animal Physiology
Baron, D.; Batista, F.; Chaffaux, S.; Cocquet, J.; Cotinot, C.; Cribiu, E.; De Baeree, E.; Guiguen, Y.; Jaubert, F.; Pailhoux, E.; Pannetier, M.; Vaiman, D.; Vigier, B.; Veita, R.; Fellous, M..
In this review, we describe recent results concerning the genetics of sex determination in mammals. Particularly, we developed the study of the FOXL2 gene and its implication in genetic anomalies in goats (PIS mutation) and humans (BPES). We present the expression of FOXL2 in the ovaries of different species.
Tipo: Journal (Paginated) Palavras-chave: QP Physiology.
Ano: 2005 URL: http://phy043.tours.inra.fr:8080/archive/00000086/
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Non-flame atomic absorption analysis of trace metal elements fixation by seric proteins of crustacean decapods IRD
Pinta, Maurice; Baron, D.; Riandey, Christian; Ghidalia, W..
Tipo: Text Palavras-chave: POLLUTION MARINE; ETUDE EXPERIMENTALE; PROTEINE; SEROLOGIE; ELEMENT EN TRACE; METAL; CONTAMINATION; METHODE D'ANALYSE; CRUSTACEA; DECAPODA.
Ano: 1978 URL: http://www.documentation.ird.fr/hor/fdi:09499
Registros recuperados: 6
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