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Development of a sampling regime for research with environmental relevance based on variability of transgene expression in plants Nature Precedings
Carla Struzyna-Schulze; Heike Mikschofsky; Wenke Mönkemeyer; Jörg Schmidtke; Kerstin Schmidt; Inge Broer.
Transgenic plants often produce proteins that are unknown in conventional crops. Therefore, it requires a fundamental analysis before approval of a new genetically modified plant is given. Since the EFSA-guidelines for risk assessment on transgenic plants provide only recommendations but no detailed instructions, we wanted to develop a valid test scheme that defines sample size and sampling organ to enable a statically valid and efficient analysis of transgene expression and its variability. The scheme will be based on data obtained for the variability in expression i. of different recombinant proteins in one variety; ii. of different integration sites of one transgene in one variety; iii. of the same recombinant protein between different varieties and...
Tipo: Poster Palavras-chave: Biotechnology; Plant Biology.
Ano: 2010 URL: http://precedings.nature.com/documents/4443/version/1
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