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Ordenar por: RelevânciaAutorTítuloAnoImprime registros no formato resumido
Registros recuperados: 4
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Diurnal variation of vascular diameter and reactivity in healthy young men BJMBR
Bau,P.F.D.; Bau,C.H.D.; Naujorks,A.A.; Rosito,G.A.; Fuchs,F.D..
The higher incidence of cardiovascular events in the morning is accompanied by an increased vascular tone. However, there are few published studies designed to evaluate the diurnal variation of vascular and endothelial parameters in healthy subjects. In the present investigation, we evaluated the diurnal variation in brachial artery diameter (BAD), flow-mediated dilation (FMD) and endothelium-independent dilation (NFMD) in a homogeneous sample of healthy non-smoker young men. Fifty subjects aged 20.8 ± 0.3 years (range: 18 to 25 years) were investigated by brachial artery ultrasound. Exclusion criteria were female gender and evidence of clinically significant health problems, including obesity. Volunteers were asked to rest and avoid fat meals as well as...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cardiovascular risk factor; Circadian rhythm; Brachial artery; Vasoconstriction; Vascular biology.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000600011
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Familial predisposition to hypertension and the association between urinary sodium excretion and blood pressure in a population-based sample of young adults BJMBR
Moraes,R.S.; Fuchs,F.D.; Dalla Costa,F.; Moreira,L.B..
The reasons for the inconsistent association between salt consumption and blood pressure levels observed in within-society surveys are not known. A total of 157 normotensive subjects aged 18 to 35 years, selected at random in a cross-sectional population-based survey, answered a structured questionnaire. They were classified as strongly predisposed to hypertension when two or more first-degree relatives had a diagnosis of hypertension. Anthropometric parameters were obtained and sitting blood pressure was determined with aneroid sphygmomanometers. Sodium and potassium excretion was measured by flame spectrophotometry in an overnight urine sample. A positive correlation between blood pressure and urinary sodium excretion was detected only in the group of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hypertension; Familial predisposition to hypertension; Urinary sodium excretion; Salt sensitivity.
Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000700010
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Reports of investigations using quantitative methods in the clinical setting: a call for papers BJMBR
Fuchs,F.D..
Tipo: Info:eu-repo/semantics/other Palavras-chave: Clinical investigation; Quantitative methods; Clinical epidemiology.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001001100001
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The corporate bias and the molding of prescription practices: the case of hypertension BJMBR
Fuchs,F.D..
Drug management of hypertension has been a noticeable example of the influence of the pharmaceutical industry on prescription practices. The worldwide leading brands of blood pressure-lowering agents are angiotensin receptor-blocking agents, although they are considered to be simply substitutes of angiotensin-converting enzyme (ACE) inhibitors. Commercial strategies have been based on the results of clinical trials sponsored by drug companies. Most of them presented distortions in their planning, presentation or interpretation that favored the drugs from the sponsor, i.e., corporate bias. Atenolol, an ineffective blood pressure agent in elderly individuals, was the comparator drug in several trials. In a re-analysis of the INSIGHT trial, deaths appeared to...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Hypertension; Blood pressure agents; Clinical trials; Ethics; Corporate bias.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000300002
Registros recuperados: 4
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