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Action of Trivalent Chromium on Rat Liver Structure. Histometric and Haematological Studies International Journal of Morphology
Silva,Rogério Ferreira da; Lopes,Ruberval A; Sala,Miguel A; Vinha,Dionísio; Regalo,Simone C. H.; Souza,Ana Maria de; Gregório,Zita Maria de O.
The trace mineral trivalent chromium (Cr3+) is an essential nutrient involved in the regulation of carbohydrate, lipid and protein metabolism via an enhancement of insulin action. The present work had as objective to characterize histopathologically and histometrically the hepatic alterations of female Wistar rats, determined by the chromium III administration in drinking water. Adult rats received ration and drinking water ad libitum containing 300 or 500 mg/l chromium III during 4 months. Control animals received only water and ration. All animals were sacrificed by lethal dose of anesthetic. Samples of liver were fixed in 10% formalin for 24 h. Tissues for microscopical pathology were processed using standard procedures. Paraffin sections prepared at 6...
Tipo: Journal article Palavras-chave: Liver; Rat; Chromium; Morphometry; Hematology.
Ano: 2006 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022006000300014
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