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Development of a Decision Support System (DSS) for an integrated test system towards the effective and competitive risk assessment on transgenic plants Nature Precedings
Christine Höflich; Andreas Müller; Jörg Schmidtke; Kerstin Schmidt; Inge Broer.
Transgenic plants need specific approaches to analyse their potential impact on environment and consumer. The procedures used to date are often too extensive and time-consuming and associated with high costs. The BioOK network was established to develop an effective and competitive risk assessment on transgenic plants based on interdisciplinary research. New and effective methods for the risk assessment were established which focus on transgene-specific effects measured in in vitro systems in the laboratory or greenhouse whenever possible. Nevertheless event-specific field experiments have to be carried out in addition to implement environmental effects e.g. on non-targets or the variability of transgene expression.

The...
Tipo: Poster Palavras-chave: Biotechnology; Bioinformatics; Plant Biology.
Ano: 2010 URL: http://precedings.nature.com/documents/4438/version/2
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Development of a Decision Support System (DSS) for an integrated test system towards the effective and competitive risk assessment on transgenic plants Nature Precedings
Christine Höflich; Andreas Müller; Jörg Schmidtke; Kerstin Schmidt; Inge Broer.
Transgenic plants need specific approaches to analyse their potential impact on environment and consumer. The procedures used to date are often too extensive and time-consuming and associated with high costs. The BioOK network was established to develop an effective and competitive risk assessment on transgenic plants based on interdisciplinary research. New and effective methods for the risk assessment were established which focus on transgene-specific effects measured in in vitro systems in the laboratory or greenhouse whenever possible. Nevertheless event-specific field experiments have to be carried out in addition to implement environmental effects e.g. on non-targets or the variability of transgene expression.

The...
Tipo: Poster Palavras-chave: Biotechnology; Bioinformatics; Plant Biology.
Ano: 2010 URL: http://precedings.nature.com/documents/4438/version/1
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Imprime registro no formato completo
Development of a sampling regime for research with environmental relevance based on variability of transgene expression in plants Nature Precedings
Carla Struzyna-Schulze; Heike Mikschofsky; Wenke Mönkemeyer; Jörg Schmidtke; Kerstin Schmidt; Inge Broer.
Transgenic plants often produce proteins that are unknown in conventional crops. Therefore, it requires a fundamental analysis before approval of a new genetically modified plant is given. Since the EFSA-guidelines for risk assessment on transgenic plants provide only recommendations but no detailed instructions, we wanted to develop a valid test scheme that defines sample size and sampling organ to enable a statically valid and efficient analysis of transgene expression and its variability. The scheme will be based on data obtained for the variability in expression i. of different recombinant proteins in one variety; ii. of different integration sites of one transgene in one variety; iii. of the same recombinant protein between different varieties and...
Tipo: Poster Palavras-chave: Biotechnology; Plant Biology.
Ano: 2010 URL: http://precedings.nature.com/documents/4443/version/1
Registros recuperados: 3
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