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Alteration of Dentate Gyrus Astrocytes in Diabetic Rats: Protective Role of Urtica dioica International Journal of Morphology
Golalipour,Mohammad Jafar; Ghafari,Soraya; Latifimoghadam,Mohammad Hossein; Kaboli,Sakineh.
Diabetes mellitus can cause astrocytes alterations in the central nervous system. Urtica dioica (Nettle) is among several species listed for their use against diabetes in folk medicine. Therefore, this study was done to evaluate the protective effect of Urtica dioica on astrocytes density of the dentate gyrus in STZ induced diabetic rats. In this experimental study, 21 male albino Wistar rats were randomly allocated equally into normal, diabetic and protective (nettle treated diabetic) groups. Hyperglycemia was induced by streptozotocin (80 mg/kg) in the animals of diabetic and treatment groups. Before induction of diabetes in animals, animals in protective group received hydroalcoholic extract of Urtica dioica (100 mg/kg/BW /day) for five days...
Tipo: Journal article Palavras-chave: Diabetes; Astrocyte; Urtica dioica; Dentate gyrus.
Ano: 2011 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000400039
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