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Increasing of Syncytial Knot and Fibrinoid Deposit in High-Cd Accumulated Human Placentas International Journal of Morphology
Phuapittayalert,Laorrat; Norkaew,Thongchai; Supanpaiboon,Wisa; Chuenchoojit,Supaporn; Hipkeao,Wiphawi; Swaddiwudhipong,Witaya; Sakulsak,Natthiya.
A toxic metal, cadmium (Cd), can accumulate in human organs. Placenta is usually used as indicator organ for Cd exposure. Therefore, we aim to investigate the different of placental morphology between the low- and high-Cd accumulated placentas. The samples were collected from 14 pregnant women who resided in low-Cd contaminated (L-Cd group) and high-Cd contaminated (H-Cd group) areas. The concentrations of Cd in blood (B-Cd), urine (U-Cd) and placentas (P-Cd) were measured by ICP-MS and AAS. The morphological appearance of placentas was examined by using routine paraffin section and H & E staining. The results showed that levels of B-Cd, U-Cd and P-Cd were significantly higher in H-Cd group than in L-Cd group (p= 0.001). Moreover, the B-Cd was...
Tipo: Journal article Palavras-chave: Cadmium; Placenta; Syncytial knot; Fibrinoid materials.
Ano: 2013 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000400011
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