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Anthocyanin-rich extract decreases indices of lipid peroxidation and DNA damage in vitamin E-depleted rats IPB - Escola Superior Agrária
Ramirez-Tortosa, Carmen; Cabrita, Luís; Andersen, Øyvind M.; Gardner, P.T.; Morrice, P.C.; Wood, S.G.; Duthie, S.J.; Collins, A.R.; Garry, G.G..
Anthocyanins are secondary plant metabolites responsible for the blue, purple, and red color of many plant tissues. The phenolic structure of anthocyanins conveys marked antioxidant activity in model systems via donation of electrons or hydrogen atoms from hydroxyl moieties to free radicals. Dietary intakes of anthocyanins may exceed 200 mg/day, however, little is known about their antioxidant potency in vivo. Consequently, the aim of this study was to establish whether anthocyanins could act as putative antioxidant micronutrients. Rats were maintained on vitamin E-deficient diets for 12 weeks in order to enhance susceptibility to oxidative damage and then repleted with rations containing a highly purified anthocyanin-rich extract at a concentration of 1...
Tipo: Article Palavras-chave: Anthocyanins; Polyphenols; Lipid peroxides; DNA damage; Antioxidants; Free radicals.
Ano: 2001 URL: http://hdl.handle.net/10198/3368
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