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Antitumoral, antioxidant and antimicrobial molecules from combretum rupicola. Repositório Alice
SANTOS, S. N.; KAVAMURA, V.; CASTANHA, R. F.; ANDREOTE, F. D.; CARVALHO, J. E.; QUEIROZ, S. C. do N. de; MELO, I. S. de.
This investigation describes the anticancer, antioxidant and antimicrobial properties of the extracts of Combretum rupicola, a native plant from Northeast of Brazil. Methanolic, ethyl acetate and chloroform extracts from leaves of C. rupicola were evaluated in relation to their potential in inhibiting the cell growth and cytotoxic properties against nine human cancer cell lines (MCF-7, NCI-ADR/RES, OVCAR-3, PC-3, HT-29, NCIH460, 786-O, UACC-62, K-562). In addition, antioxidant activity of these extracts was measured using DPPH as radical scavenging assay and the ntimicrobial activities against nine pathogens were tested by agar diffusion method. Preliminary results showed that the this plant demonstrates to have moderate activity against bacteria but, on...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Combretum rupicola; Planta medicinal; Extrato vegetal; Plant extracts; Medicinal plants; Antioxidant activity; Antineoplastic agents.
Ano: 2013 URL: http://www.alice.cnptia.embrapa.br/handle/doc/950033
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Atividade antitumoral de biomoléculas obtidas de Fusarium oxysporum, um endofítico de Combretum leprosum, planta nativa do semiárido brasileiro. Repositório Alice
SANTOS, S. N.; FERRARIS, F. K.; KAVAMURA, V.; TAKETANI, R. G.; LANÇONI, M. D.; DINI-ANDREOTE, F.; HENRRIQUES, M. das G. M. O.; MELO, I. S. de.
2011
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Semiárido brasileiro; Fusarium oxysporum; Combretum; Antineoplastic agents.
Ano: 2011 URL: http://www.alice.cnptia.embrapa.br/handle/doc/917605
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SCORPION VENOM: NEW PROMISE IN THE TREATMENT OF CANCER Acta biol.Colomb.
GÓMEZ RAVE,Lyz Jenny; MUÑOZ BRAVO,Adriana Ximena; SIERRA CASTRILLO,Jhoalmis; ROMÁN MARÍN,Laura Melisa; CORREDOR PEREIRA,Carlos.
ABSTRACT Cancer is a public health problem due to its high worldwide morbimortality. Current treatment protocols do not guarantee complete remission, which has prompted to search for new and more effective antitumoral compounds. Several substances exhibiting cytostatic and cytotoxic effects over cancer cells might contribute to the treatment of this pathology. Some studies indicate the presence of such substances in scorpion venom. In this review, we report characteristics of the principal scorpion venom components found in recent literature and their potential activity against tumor cells. There are different toxin groups present in the venom, and it seems that their mode of actions involves ionic channel blocking, disruption of the cell membrane...
Tipo: Journal article Palavras-chave: Anti-infective agents; Antineoplastic agents; Arachnida; Molecular biology; Peptides.
Ano: 2019 URL: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0120-548X2019000200213
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