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Biological processes related to ribosome and mitochondrial functions might be involved in the osteochondrosis latens manifestation in gilts. Repositório Alice
IBELLI, A. M. G.; PEIXOTO, J. de O.; SAVOLDI, I. R.; CARMO, K. B. do; MORES, N.; MORES, M. A. Z.; CANTAO, M. E.; COUTINHO, L. L.; LEDUR, M. C..
Abstract: The articular osteochondrosis (OC) is a disturbance of endochondral ossification occurring in humans and livestock animals. In pigs, OC is one of the major causes of leg weakness, leading to economic losses and reducing the animal welfare. The aim of this study was to evaluate the differential gene expression related to OC latens in femoral articular cartilage in swine. Thus, samples of MS115 5-months-old gilts, normal (control group) and affected with OC latens (affected group), were collected and submitted to histopathological and gene expression analysis. A total of 1,734 genes was differentially expressed (DE) between the two groups. Several biological processes (BP) were enriched including those already known as involved with OC, such as...
Tipo: Artigo em anais de congresso (ALICE) Palavras-chave: Desenvolvimento ósseo; Características do fêmur; Osteocondrose articular; Problemas de locomoção; Locomotor problems; RNA-Seq; Melhoramento Genético Animal; Suíno; Gene; Osso; Fêmur; Animal genetic resources; Swine; Osteochondrosis; Gene expression; Lameness; Leg weakness.
Ano: 2018 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1093227
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Genome-wide association study for femur-related traits in broilers. Repositório Alice
ONO, R. K.; IBELLI, A. M. G.; CANTAO, M. E.; PEIXOTO, J. de O.; SOLLERO, B. P.; SUREK, D.; MOREIRA, G. C. M.; GODOY, T. F.; COUTINHO, L. L.; LEDUR, M. C..
Abstract: Due to the intense selection for heavier and faster growing broilers, metabolic disorders such as skeletal problems became a worldwide concern. Advances in genome-wide association study (GWAS) methodologies increased the possibility of elucidating the genetic architecture controlling bone integrity traits. Therefore, the aim of this study was to perform a GWAS to identify potential genetic markers and candidate genes associated with femur traits in a paternal broiler line developed by Embrapa. To this, three femur bone-related traits were evaluated in 1,433 chickens: dry matter (FDM), ash content (FAC) and breaking strength (FBS). Chickens were genotyped using the 600K Affymetrix® Axiom® HD panel. A total of 16 regions associated to FAC, being a...
Tipo: Artigo em anais de congresso (ALICE) Palavras-chave: Integridade óssea; Características do fêmur; Associação genômica; QTLs; Melhoramento Genético Animal; Frango de Corte; Formação Óssea; Fêmur; Animal genetic resources; Broiler chickens; Bone metabolism; Quantitative trait loci.
Ano: 2018 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1093205
Registros recuperados: 2
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